{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T17:18:46Z","timestamp":1764782326665,"version":"build-2065373602"},"reference-count":38,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Zhenhong Jia","award":["2019YFC1606100","61665012"],"award-info":[{"award-number":["2019YFC1606100","61665012"]}]},{"name":"Jiajia Wang","award":["TCBS202049"],"award-info":[{"award-number":["TCBS202049"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>In this paper, carbon quantum dot-labelled \u03b2-lactoglobulin antibodies were used for refractive index magnification, and \u03b2-lactoglobulin was detected by angle spectroscopy. In this method, the detection light is provided by a He-Ne laser whose central wavelength is the same as that of the porous silicon microcavity device, and the light source was changed to a parallel beam to illuminate the porous silicon microcavity\u2019 surface by collimating beam expansion, and the reflected light was received on the porous silicon microcavity\u2019 surface by a detector. The angle corresponding to the smallest luminous intensity before and after the onset of immune response was measured by a detector for different concentrations of \u03b2-lactoglobulin antigen and carbon quantum dot-labelled \u03b2-lactoglobulin antibodies, and the relationship between the variation in angle before and after the immune response was obtained for different concentrations of the \u03b2-lactoglobulin antigen. The results of the experiment present that the angle variations changed linearly with increasing \u03b2-lactoglobulin antigen concentration before and after the immune response. The limit of detection of \u03b2-lactoglobulin by this method was 0.73 \u03bcg\/L, indicating that the method can be used to detect \u03b2-lactoglobulin quickly and conveniently at low cost.<\/jats:p>","DOI":"10.3390\/s22051912","type":"journal-article","created":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T21:25:14Z","timestamp":1646169914000},"page":"1912","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Detection of \u03b2-Lactoglobulin by a Porous Silicon Microcavity Biosensor Based on the Angle Spectrum"],"prefix":"10.3390","volume":"22","author":[{"given":"Lanlan","family":"Bai","sequence":"first","affiliation":[{"name":"School of Physical Science and Technology, Xinjiang University, Urumqi 830046, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun","family":"Gao","sequence":"additional","affiliation":[{"name":"School of Physical Science and Technology, Xinjiang University, Urumqi 830046, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiajia","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Information Science and Engineering, Xinjiang University, Urumqi 830046, China"},{"name":"The Key Laboratory of Signal Detection and Processing, Xinjiang Uygur Autonomous Region, Xinjiang University, Urumqi 830046, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tuerxunnayi","family":"Aili","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology, Xinjiang University, Urumqi 830046, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenhong","family":"Jia","sequence":"additional","affiliation":[{"name":"School of Information Science and Engineering, Xinjiang University, Urumqi 830046, China"},{"name":"The Key Laboratory of Signal Detection and Processing, Xinjiang Uygur Autonomous Region, Xinjiang University, Urumqi 830046, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyi","family":"Lv","sequence":"additional","affiliation":[{"name":"The Key Laboratory of Signal Detection and Processing, Xinjiang Uygur Autonomous Region, Xinjiang University, Urumqi 830046, China"},{"name":"School of Software, Xinjiang University, Urumqi 830046, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaohui","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Information Science and Engineering, Xinjiang University, Urumqi 830046, China"},{"name":"The Key Laboratory of Signal Detection and Processing, Xinjiang Uygur Autonomous Region, Xinjiang University, Urumqi 830046, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Yang","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology, Xinjiang University, Urumqi 830046, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,3,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1111\/j.1398-9995.1990.tb00944.x","article-title":"A prospective study of cow milk allergy in Danish infants during the first 3 years of life. 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