{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T00:45:10Z","timestamp":1774658710730,"version":"3.50.1"},"reference-count":37,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2022,3,2]],"date-time":"2022-03-02T00:00:00Z","timestamp":1646179200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["LE 817\/41-1"],"award-info":[{"award-number":["LE 817\/41-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002261","name":"Russian Foundation for Basic Research","doi-asserted-by":"publisher","award":["20-58-12006"],"award-info":[{"award-number":["20-58-12006"]}],"id":[{"id":"10.13039\/501100002261","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>The detection of muscle contraction and the estimation of muscle force are essential tasks in robot-assisted rehabilitation systems. The most commonly used method to investigate muscle contraction is surface electromyography (EMG), which, however, shows considerable disadvantages in predicting the muscle force, since unpredictable factors may influence the detected force but not necessarily the EMG data. Electrical impedance myography (EIM) investigates the change in electrical impedance during muscle activities and is another promising technique to investigate muscle functions. This paper introduces the design, development, and evaluation of a device that performs EMG and EIM simultaneously for more robust measurement of muscle conditions subject to artifacts. The device is light, wearable, and wireless and has a modular design, in which the EMG, EIM, micro-controller, and communication modules are stacked and interconnected through connectors. As a result, the EIM module measures the bioimpedance between 20 and 200 \u03a9 with an error of less than 5% at 140 SPS. The settling time during the calibration phase of this module is less than 1000 ms. The EMG module captures the spectrum of the EMG signal between 20\u2013150 Hz at 1 kSPS with an SNR of 67 dB. The micro-controller and communication module builds an ARM-Cortex M3 micro-controller which reads and transfers the captured data every 1 ms over RF (868 Mhz) with a baud rate of 500 kbps to a receptor connected to a PC. Preliminary measurements on a volunteer during leg extension, walking, and sit-to-stand showed the potential of the system to investigate muscle function by combining simultaneous EMG and EIM.<\/jats:p>","DOI":"10.3390\/s22051941","type":"journal-article","created":{"date-parts":[[2022,3,2]],"date-time":"2022-03-02T22:53:25Z","timestamp":1646261605000},"page":"1941","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["A Wearable, Multi-Frequency Device to Measure Muscle Activity Combining Simultaneous Electromyography and Electrical Impedance Myography"],"prefix":"10.3390","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3961-2173","authenticated-orcid":false,"given":"Chuong","family":"Ngo","sequence":"first","affiliation":[{"name":"Medical Information Technology, RWTH Aachen University, Pauwelsstr. 20, 52074 Aachen, Germany"}]},{"given":"Carlos","family":"Munoz","sequence":"additional","affiliation":[{"name":"Medical Information Technology, RWTH Aachen University, Pauwelsstr. 20, 52074 Aachen, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2487-0962","authenticated-orcid":false,"given":"Markus","family":"Lueken","sequence":"additional","affiliation":[{"name":"Medical Information Technology, RWTH Aachen University, Pauwelsstr. 20, 52074 Aachen, Germany"}]},{"given":"Alfred","family":"H\u00fclkenberg","sequence":"additional","affiliation":[{"name":"Medical Information Technology, RWTH Aachen University, Pauwelsstr. 20, 52074 Aachen, Germany"}]},{"given":"Cornelius","family":"Bollheimer","sequence":"additional","affiliation":[{"name":"Department of Geriatrics, University Hospital Aachen, 52074 Aachen, Germany"}]},{"given":"Andrey","family":"Briko","sequence":"additional","affiliation":[{"name":"Department of Medical and Technical Information Technology, Bauman Moscow State Technical University, 105005 Moscow, Russia"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6715-7668","authenticated-orcid":false,"given":"Alexander","family":"Kobelev","sequence":"additional","affiliation":[{"name":"Department of Medical and Technical Information Technology, Bauman Moscow State Technical University, 105005 Moscow, Russia"}]},{"given":"Sergey","family":"Shchukin","sequence":"additional","affiliation":[{"name":"Department of Medical and Technical Information Technology, Bauman Moscow State Technical University, 105005 Moscow, Russia"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6898-6887","authenticated-orcid":false,"given":"Steffen","family":"Leonhardt","sequence":"additional","affiliation":[{"name":"Medical Information Technology, RWTH Aachen University, Pauwelsstr. 20, 52074 Aachen, Germany"}]}],"member":"1968","published-online":{"date-parts":[[2022,3,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1615\/CritRevBiomedEng.2014010453","article-title":"A review of lower extremity assistive robotic exoskeletons in rehabilitation therapy","volume":"41","author":"Chen","year":"2013","journal-title":"Crit. 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