{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T17:46:54Z","timestamp":1776534414122,"version":"3.51.2"},"reference-count":26,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2022,4,14]],"date-time":"2022-04-14T00:00:00Z","timestamp":1649894400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>The maintenance of uric acid levels is crucial for the human body. In this study, the feasibility of using portable ultraviolet (UV) spectrophotometry to measure the uric acid of spot urine without the need to add reagents has been demonstrated for the first time. UV spectral analysis has been used to inspect the uric acid concentration in urine. It is found that the absorption spectrum of urine has a high correlation with the concentration of uric acid at a wavelength of around 290\u2013300 nm. Uric acid levels measured with a spectral analyzer compared to uric acid concentrations measured with a traditional biochemical analysis showed good agreement. The portable prototype is label-free and capable of displaying the inspection result of each measurement within 10 s. In the long run, this device can assist people in checking uric acid levels of spot urine with higher frequency and can adjust diet or medication in real time for more efficient health management.<\/jats:p>","DOI":"10.3390\/s22083009","type":"journal-article","created":{"date-parts":[[2022,4,19]],"date-time":"2022-04-19T02:39:31Z","timestamp":1650335971000},"page":"3009","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Label-Free Uric Acid Estimation of Spot Urine Using Portable Device Based on UV Spectrophotometry"],"prefix":"10.3390","volume":"22","author":[{"given":"Tsung-Jui","family":"Lin","sequence":"first","affiliation":[{"name":"Taiwan RedEye Biomedical Inc., Hsinchu City 300, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6777-126X","authenticated-orcid":false,"given":"Kai-Ting","family":"Yen","sequence":"additional","affiliation":[{"name":"Department of Electrophysics, National Yang Ming Chiao Tung University, Hsinchu City 300093, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chien-Fan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Electrophysics, National Yang Ming Chiao Tung University, Hsinchu City 300093, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuo-Ting","family":"Yan","sequence":"additional","affiliation":[{"name":"Taiwan RedEye Biomedical Inc., Hsinchu City 300, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4891-3303","authenticated-orcid":false,"given":"Kuan-Wei","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Electrophysics, National Yang Ming Chiao Tung University, Hsinchu City 300093, Taiwan"},{"name":"College of Artificial Intelligence, National Yang Ming Chiao Tung University, Tainan City 711010, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2564-9653","authenticated-orcid":false,"given":"Ya-Ling","family":"Chiang","sequence":"additional","affiliation":[{"name":"Taiwan RedEye Biomedical Inc., Hsinchu City 300, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,4,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1038\/s41584-020-0441-1","article-title":"Global Epidemiology of Gout: Prevalence, Incidence, Treatment Patterns and Risk Factors","volume":"16","author":"Dehlin","year":"2020","journal-title":"Nat. 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