{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T22:34:58Z","timestamp":1765233298636,"version":"build-2065373602"},"reference-count":21,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2022,4,14]],"date-time":"2022-04-14T00:00:00Z","timestamp":1649894400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ministry of Education","award":["2019R1A6C1010033 and 2021R1A6C103B392"],"award-info":[{"award-number":["2019R1A6C1010033 and 2021R1A6C103B392"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>The human skin sebum suggests that it (along with other epidermal surface lipids) plays a role in skin barrier formation, the moderation of cutaneous inflammation, and antimicrobial defense. Various methods have been developed for collecting and measuring skin sebum. We tested methods of detection using \u201ccolor intensity\u201d, by staining the skin casual sebum. This process was conducted in three steps; first, the selection of materials for sebum collection; second, staining the collected sebum; third, the development of a device that can measure the level of stained sebum. A plastic film was used to effectively collect sebum that increased with the replacement time of the sebum. In addition, the collected sebum was stained with Oil Red O (ORO) and checked with RGB; as a result, the R2 value was higher than 0.9. It was also confirmed that the correlation value was higher than 0.9 in the comparison result with Sebumeter\u00ae, which is a common standard technology. Finally, it was confirmed that the R2 value was higher than 0.9 in the detection value using the sensor. In conclusion, we have proven the proof of concept (PoC) for this method, and we would like to introduce an effective sebum measurement method that differs from the existing method.<\/jats:p>","DOI":"10.3390\/s22083016","type":"journal-article","created":{"date-parts":[[2022,4,19]],"date-time":"2022-04-19T02:39:31Z","timestamp":1650335971000},"page":"3016","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["A Real-Time Detection Device for the Rapid Quantification of Skin Casual Sebum Using the Oil Red O Staining Method"],"prefix":"10.3390","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2778-5517","authenticated-orcid":false,"given":"Kung","family":"Ahn","sequence":"first","affiliation":[{"name":"HuNBiome Co., Ltd., R&D Center, Gasan Digital 1-ro, Geumcheon-gu, Seoul 08507, Korea"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0354-0478","authenticated-orcid":false,"given":"Sangjin","family":"Han","sequence":"additional","affiliation":[{"name":"HuNBiome Co., Ltd., R&D Center, Gasan Digital 1-ro, Geumcheon-gu, Seoul 08507, Korea"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3767-962X","authenticated-orcid":false,"given":"Kyeongeui","family":"Yun","sequence":"additional","affiliation":[{"name":"HuNBiome Co., Ltd., R&D Center, Gasan Digital 1-ro, Geumcheon-gu, Seoul 08507, Korea"}]},{"given":"Wooseok","family":"Lee","sequence":"additional","affiliation":[{"name":"Center for Bio-Medical Engineering Core Facility, Dankook University, Cheonan 31116, Korea"}]},{"given":"Dong-Geol","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Microbiology, College of Science & Technology, Dankook University, Cheonan 31116, Korea"},{"name":"R&I Center, COSMAX BTI, Pangyo-ro 255, Bundang-gu, Seoungnam-si 13486, Korea"}]},{"given":"So Min","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Bundang-gu, Seongnam 13620, Korea"},{"name":"H&BIO KSRC (H&BIO Korean Skin Research Center), Bundang-gu, Seongnam 13605, Korea"}]},{"given":"Young-Bong","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Chemistry, College of Science & Technology, Dankook University, Cheonan 31116, Korea"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6791-2408","authenticated-orcid":false,"given":"Kyudong","family":"Han","sequence":"additional","affiliation":[{"name":"HuNBiome Co., Ltd., R&D Center, Gasan Digital 1-ro, Geumcheon-gu, Seoul 08507, Korea"},{"name":"Center for Bio-Medical Engineering Core Facility, Dankook University, Cheonan 31116, Korea"},{"name":"Department of Microbiology, College of Science & Technology, Dankook University, Cheonan 31116, Korea"}]},{"given":"Yong Ju","family":"Ahn","sequence":"additional","affiliation":[{"name":"HuNBiome Co., Ltd., R&D Center, Gasan Digital 1-ro, Geumcheon-gu, Seoul 08507, Korea"}]}],"member":"1968","published-online":{"date-parts":[[2022,4,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1111\/jocd.12345","article-title":"A review of the role of sebum in the mechanism of acne pathogenesis","volume":"16","author":"Li","year":"2017","journal-title":"J. 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