{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T01:40:11Z","timestamp":1767922811295,"version":"3.49.0"},"reference-count":35,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T00:00:00Z","timestamp":1656288000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Natural Science Foundation of China","award":["21904091"],"award-info":[{"award-number":["21904091"]}]},{"name":"National Natural Science Foundation of China","award":["62001318"],"award-info":[{"award-number":["62001318"]}]},{"name":"National Natural Science Foundation of China","award":["BK20200876"],"award-info":[{"award-number":["BK20200876"]}]},{"name":"National Natural Science Foundation of China","award":["2020M671578"],"award-info":[{"award-number":["2020M671578"]}]},{"name":"Natural Science Foundation of Jiangsu Province","award":["21904091"],"award-info":[{"award-number":["21904091"]}]},{"name":"Natural Science Foundation of Jiangsu Province","award":["62001318"],"award-info":[{"award-number":["62001318"]}]},{"name":"Natural Science Foundation of Jiangsu Province","award":["BK20200876"],"award-info":[{"award-number":["BK20200876"]}]},{"name":"Natural Science Foundation of Jiangsu Province","award":["2020M671578"],"award-info":[{"award-number":["2020M671578"]}]},{"DOI":"10.13039\/501100004608","name":"Chinese Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["21904091"],"award-info":[{"award-number":["21904091"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"Chinese Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["62001318"],"award-info":[{"award-number":["62001318"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"Chinese Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["BK20200876"],"award-info":[{"award-number":["BK20200876"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"Chinese Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2020M671578"],"award-info":[{"award-number":["2020M671578"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Drift-time ion mobility spectrometer (DT-IMS) is a promising technology for gas detection and analysis in the form of miniaturized instrument. Analytes may exist in the form of positively or negatively charged ions according to their chemical composition and ionization condition, and therefore require both polarity of electric field for the detection. In this work the polarity switching of a drift-time ion mobility spectrometer based on a direct current (DC) corona discharge ionization source was investigated, with novel solutions for both the control of ion shutter and the stabilization of aperture grid. The drift field is established by employing a switchable high voltage power supply and a serial of voltage regulator diode, with optocouplers to drive the ion shutter when the polarity is switched. The potential of aperture grid is stabilized during the polarity switching by the use of four diodes to avoid unnecessary charging cycle of the aperture grid capacitor. Based on the proposed techniques, the developed DT-IMS with 50 mm drift path is able to switch its polarity in 10 ms and acquire mobility spectrum after 10 ms of stabilization. Coupled with a thermal desorption sampler, limit of detection (LoD) of 0.1 ng was achieved for ketamine and TNT. Extra benefits include single calibration substance for both polarities and largely simplified pneumatic design, together with the reduction of second drift tube and its accessories. This work paved the way towards further miniaturization of DT-IMS without compromise of performance.<\/jats:p>","DOI":"10.3390\/s22134866","type":"journal-article","created":{"date-parts":[[2022,6,28]],"date-time":"2022-06-28T00:07:02Z","timestamp":1656374822000},"page":"4866","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Ultra-Fast Polarity Switching, Non-Radioactive Drift Tube for the Miniaturization of Drift-Time Ion Mobility Spectrometer"],"prefix":"10.3390","volume":"22","author":[{"given":"Lingfeng","family":"Li","sequence":"first","affiliation":[{"name":"School of Electronic and Information Engineering, Soochow University, Suzhou 215006, China"}]},{"given":"Hao","family":"Gu","sequence":"additional","affiliation":[{"name":"School of Electronic and Information Engineering, Soochow University, Suzhou 215006, China"}]},{"given":"Yanzhen","family":"Lv","sequence":"additional","affiliation":[{"name":"School of Electronic and Information Engineering, Soochow University, Suzhou 215006, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4866-7053","authenticated-orcid":false,"given":"Yunjing","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Electronic and Information Engineering, Soochow University, Suzhou 215006, China"}]},{"given":"Xingli","family":"He","sequence":"additional","affiliation":[{"name":"School of Electronic and Information Engineering, Soochow University, Suzhou 215006, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6423-2981","authenticated-orcid":false,"given":"Peng","family":"Li","sequence":"additional","affiliation":[{"name":"School of Electronic and Information Engineering, Soochow University, Suzhou 215006, China"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Eiceman, G.A., and Karpas, Z. 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