{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T04:31:19Z","timestamp":1772253079596,"version":"3.50.1"},"reference-count":32,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2022,6,29]],"date-time":"2022-06-29T00:00:00Z","timestamp":1656460800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Union\u2019s Horizon 2020 Research and Innovation Programme","award":["960251"],"award-info":[{"award-number":["960251"]}]},{"name":"European Union\u2019s Horizon 2020 Research and Innovation Programme","award":["DIN2019-010857\/AEI\/10.13039\/501100011033"],"award-info":[{"award-number":["DIN2019-010857\/AEI\/10.13039\/501100011033"]}]},{"DOI":"10.13039\/501100004837","name":"Spanish Ministry of Science and Innovation","doi-asserted-by":"publisher","award":["960251"],"award-info":[{"award-number":["960251"]}],"id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004837","name":"Spanish Ministry of Science and Innovation","doi-asserted-by":"publisher","award":["DIN2019-010857\/AEI\/10.13039\/501100011033"],"award-info":[{"award-number":["DIN2019-010857\/AEI\/10.13039\/501100011033"]}],"id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>This study assesses the efficacy of detecting colorectal cancer precursors or polyps in an ex vivo human colon model with a microwave colonoscopy algorithm. Nowadays, 22% of polyps go undetected with conventional colonoscopy, and the risk of cancer after a negative colonoscopy can be up to 7.9%. We developed a microwave colonoscopy device that consists of a cylindrical ring-shaped switchable microwave antenna array that can be attached to the tip of a conventional colonoscope as an accessory. The accessory is connected to an external unit that allows successive measurements of the colon and processes the measurements with a microwave imaging algorithm. An acoustic signal is generated when a polyp is detected. Fifteen ex vivo freshly excised human colons with cancer (n = 12) or polyps (n = 3) were examined with the microwave-assisted colonoscopy system simulating a real colonoscopy exploration. After the experiment, the dielectric properties of the specimens were measured with a coaxial probe and the samples underwent a pathology analysis. The results show that all the neoplasms were detected with a sensitivity of 100% and specificity of 87.4%.<\/jats:p>","DOI":"10.3390\/s22134902","type":"journal-article","created":{"date-parts":[[2022,6,29]],"date-time":"2022-06-29T22:43:28Z","timestamp":1656542608000},"page":"4902","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["MiWEndo: Evaluation of a Microwave Colonoscopy Algorithm for Early Colorectal Cancer Detection in Ex Vivo Human Colon Models"],"prefix":"10.3390","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8751-5378","authenticated-orcid":false,"given":"Marta","family":"Guardiola","sequence":"first","affiliation":[{"name":"MiWEndo Solutions S.L., 08014 Barcelona, Spain"}]},{"given":"Walid","family":"Dghoughi","sequence":"additional","affiliation":[{"name":"MiWEndo Solutions S.L., 08014 Barcelona, Spain"}]},{"given":"Roberto","family":"Sont","sequence":"additional","affiliation":[{"name":"MiWEndo Solutions S.L., 08014 Barcelona, Spain"}]},{"given":"Alejandra","family":"Garrido","sequence":"additional","affiliation":[{"name":"MiWEndo Solutions S.L., 08014 Barcelona, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4481-8512","authenticated-orcid":false,"given":"Sergi","family":"Marcoval","sequence":"additional","affiliation":[{"name":"MiWEndo Solutions S.L., 08014 Barcelona, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2188-715X","authenticated-orcid":false,"given":"Luz Mar\u00eda","family":"Neira","sequence":"additional","affiliation":[{"name":"MiWEndo Solutions S.L., 08014 Barcelona, Spain"}]},{"given":"Ignasi","family":"Belda","sequence":"additional","affiliation":[{"name":"MiWEndo Solutions S.L., 08014 Barcelona, Spain"}]},{"given":"Gl\u00f2ria","family":"Fern\u00e1ndez-Esparrach","sequence":"additional","affiliation":[{"name":"MiWEndo Solutions S.L., 08014 Barcelona, Spain"},{"name":"Endoscopy Unit, Gastroenterology Department, Hospital Cl\u00ednic, University of Barcelona, 08036 Barcelona, Spain"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,29]]},"reference":[{"key":"ref_1","first-page":"2019","article-title":"Global Cancer Observatory: Cancer Today","volume":"3","author":"Ferlay","year":"2018","journal-title":"Int. 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