{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T00:51:12Z","timestamp":1760230272967,"version":"build-2065373602"},"reference-count":48,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T00:00:00Z","timestamp":1658188800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"VA Portland Health Care System","award":["#I01 CX002022","#1K2 RX002947","NIH P30 AG024978","NIH P30 AG066518","NIH K25 AG071841"],"award-info":[{"award-number":["#I01 CX002022","#1K2 RX002947","NIH P30 AG024978","NIH P30 AG066518","NIH K25 AG071841"]}]},{"name":"Hartford Gerontological Center","award":["#I01 CX002022","#1K2 RX002947","NIH P30 AG024978","NIH P30 AG066518","NIH K25 AG071841"],"award-info":[{"award-number":["#I01 CX002022","#1K2 RX002947","NIH P30 AG024978","NIH P30 AG066518","NIH K25 AG071841"]}]},{"name":"U.S. Department of Energy Lighting R&amp;D Program","award":["#I01 CX002022","#1K2 RX002947","NIH P30 AG024978","NIH P30 AG066518","NIH K25 AG071841"],"award-info":[{"award-number":["#I01 CX002022","#1K2 RX002947","NIH P30 AG024978","NIH P30 AG066518","NIH K25 AG071841"]}]},{"name":"Roybal Center","award":["#I01 CX002022","#1K2 RX002947","NIH P30 AG024978","NIH P30 AG066518","NIH K25 AG071841"],"award-info":[{"award-number":["#I01 CX002022","#1K2 RX002947","NIH P30 AG024978","NIH P30 AG066518","NIH K25 AG071841"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Sleep disturbances are common in older adults and may contribute to disease progression in certain populations (e.g., Alzheimer\u2019s disease). Light therapy is a simple and cost-effective intervention to improve sleep. Primary barriers to light therapy are: (1) poor acceptability of the use of devices, and (2) inflexibility of current devices to deliver beyond a fixed light spectrum and throughout the entirety of the day. However, dynamic, tunable lighting integrated into the native home lighting system can potentially overcome these limitations. Herein, we describe our protocol to implement a whole-home tunable lighting system installed throughout the homes of healthy older adults already enrolled in an existing study with embedded home assessment platforms (Oregon Center for Aging &amp; Technology\u2014ORCATECH). Within ORCATECH, continuous data on room location, activity, sleep, and general health parameters are collected at a minute-to-minute resolution over years of participation. This single-arm longitudinal protocol collected participants\u2019 light usage in addition to ORCATECH outcome measures over a several month period before and after light installation. The protocol was implemented with four subjects living in three ORCATECH homes. Technical\/usability challenges and feasibility\/acceptability outcomes were explored. The successful implementation of our protocol supports the feasibility of implementing and integrating tunable whole-home lighting systems into an automated home-based assessment platform for continuous data collection of outcome variables, including long-term sleep measures. Challenges and iterative approaches are discussed. This protocol will inform the implementation of future clinical intervention trials using light therapy in patients at risk for developing Alzheimer\u2019s disease and related conditions.<\/jats:p>","DOI":"10.3390\/s22145372","type":"journal-article","created":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T05:37:53Z","timestamp":1658209073000},"page":"5372","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Tunable White Light for Elders (TWLITE): A Protocol Demonstrating Feasibility and Acceptability for Deployment, Remote Data Collection, and Analysis of a Home-Based Lighting Intervention in Older Adults"],"prefix":"10.3390","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6992-6851","authenticated-orcid":false,"given":"Jonathan E.","family":"Elliott","sequence":"first","affiliation":[{"name":"VA Portland Health Care System, Research Service, Portland, OR 97239, USA"},{"name":"Department of Neurology, Oregon Health & Science University, Portland, OR 97239, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolyn E.","family":"Tinsley","sequence":"additional","affiliation":[{"name":"VA Portland Health Care System, Research Service, Portland, OR 97239, USA"},{"name":"Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR 97239, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina","family":"Reynolds","sequence":"additional","affiliation":[{"name":"Department of Neurology, Oregon Health & Science University, Portland, OR 97239, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Randall J.","family":"Olson","sequence":"additional","affiliation":[{"name":"VA Portland Health Care System, Research Service, Portland, OR 97239, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6421-5874","authenticated-orcid":false,"given":"Kristianna B.","family":"Weymann","sequence":"additional","affiliation":[{"name":"School of Nursing, Oregon Health & Science University, Portland, OR 97239, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wan-Tai M.","family":"Au-Yeung","sequence":"additional","affiliation":[{"name":"Department of Neurology, Oregon Health & Science University, Portland, OR 97239, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3586-2105","authenticated-orcid":false,"given":"Andrea","family":"Wilkerson","sequence":"additional","affiliation":[{"name":"Pacific Northwest National Laboratory, Portland, OR 97239, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey A.","family":"Kaye","sequence":"additional","affiliation":[{"name":"Department of Neurology, Oregon Health & Science University, Portland, OR 97239, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3876-3196","authenticated-orcid":false,"given":"Miranda M.","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Neurology, Oregon Health & Science University, Portland, OR 97239, USA"},{"name":"Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR 97239, USA"},{"name":"Oregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, OR 97239, USA"},{"name":"Pulmonary and Critical Care Medicine, Oregon Health & Science University, Portland, OR 97239, USA"},{"name":"VA Portland Health Care System, Mental Illness Research Education and Clinical Center, Neurology, National Center for Rehabilitative Auditory Research, Portland, OR 97239, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1017\/S1041610209009120","article-title":"Sleep disturbances in older adults with mild cognitive impairment","volume":"21","author":"Hudon","year":"2009","journal-title":"Int. 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