{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T13:13:41Z","timestamp":1780406021305,"version":"3.54.1"},"reference-count":21,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2022,8,18]],"date-time":"2022-08-18T00:00:00Z","timestamp":1660780800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Spanish Government","award":["PID2019-106097GB-I00\/AEI\/10.13039\/501100011033"],"award-info":[{"award-number":["PID2019-106097GB-I00\/AEI\/10.13039\/501100011033"]}]},{"name":"Spanish Government","award":["RTI2018-095855-B-I00"],"award-info":[{"award-number":["RTI2018-095855-B-I00"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>The present paper addresses the development and use of a new potentiometric electronic tongue for both qualitative and quantitative characterization of natural mineral waters. The electronic tongue is particularly related to the conductivity and ion content of\/in the water sample. The analytical system is based on six ion-selective electrodes whose membranes are formulated to provide either cationic or anionic response and considering plasticizers with different dielectric constants (bis(2-ethylhexyl) sebacate, 2-nitrophenyl octyl ether or tricresylphosphate), while keeping the polymeric matrix, i.e., poly(vinyl chloride). Notably, the absence of any ionophore in the membrane provides a general response profile, i.e., no selectivity toward any special ion, which is convenient for the realization of an effective electronic tongue. The dynamic response of the tongue toward water samples of different chemical compositions and geographical locations has been obtained. At the optimized experimental conditions, the tongue presents acceptable repeatability and reproducibility (absence of hysteresis). The principal component analysis of the final potential values observed with the six electrodes allows for the differentiation and classification of the samples according to their conductivity, which is somehow related to the mineralization. Moreover, quantitative determination of the six main ions in the water samples (i.e., chloride, nitrate, hydrogen carbonate, sulfate, sodium, calcium, and magnesium) is possible by means of a simple linear calibration (and cross-validation) model.<\/jats:p>","DOI":"10.3390\/s22166204","type":"journal-article","created":{"date-parts":[[2022,8,18]],"date-time":"2022-08-18T23:28:41Z","timestamp":1660865321000},"page":"6204","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Potentiometric Electronic Tongue for Quantitative Ion Analysis in Natural Mineral Waters"],"prefix":"10.3390","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3858-8466","authenticated-orcid":false,"given":"Mar\u00eda","family":"Cuartero","sequence":"first","affiliation":[{"name":"Department of Chemistry, School of Engineering Science in Chemistry, Biochemistry and Health, KTH Royal Institute of Technology, Teknikringen 30, SE-100 44 Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9107-1952","authenticated-orcid":false,"given":"Alberto","family":"Ruiz","sequence":"additional","affiliation":[{"name":"Department of Informatics and Systems, University of Murcia, 30100 Murcia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Gali\u00e1n","sequence":"additional","affiliation":[{"name":"Department of Analytical Chemistry, University of Murcia, 30100 Murcia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2980-7652","authenticated-orcid":false,"given":"Joaqu\u00edn A.","family":"Ortu\u00f1o","sequence":"additional","affiliation":[{"name":"Department of Analytical Chemistry, University of Murcia, 30100 Murcia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,8,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1002\/j.1551-8833.2007.tb07930.x","article-title":"Understanding the basics of tap water taste","volume":"99","author":"Burlingame","year":"2007","journal-title":"J. Am. Water Work. Assoc."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.watres.2012.10.040","article-title":"Influence of minerals on the taste of bottled and tap water: A chemometric approach","volume":"47","author":"Platikanov","year":"2013","journal-title":"Water Res."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Ward, M.H., Jones, R.R., Brender, J.D., de Kok, T.M., Weyer, P.J., Nolan, B.T., Villanueva, C.M., and van Breda, S.G. (2018). Drinking Water Nitrate and Human Health: An Updated Review. Int. J. Environ. Res. Public Health, 15.","DOI":"10.3390\/ijerph15071557"},{"key":"ref_4","first-page":"173","article-title":"Natural mineral waters: Chemical characteristics and health effects","volume":"13","author":"Quattrini","year":"2016","journal-title":"Clin. Cases Miner. Bone Metab."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1017\/S0007114508061515","article-title":"The composition of mineral waters sourced from Europe and North America in respect to bone health: Composition of mineral water optimal for bone","volume":"101","author":"Wynn","year":"2008","journal-title":"Br. J. Nutr."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1351\/pac200577111965","article-title":"Nonspecific sensor arrays (\u201celectronic tongue\u201d) for chemical analysis of liquids (IUPAC Technical Report)","volume":"77","author":"Vlasov","year":"2005","journal-title":"Pure Appl. Chem."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"121110","DOI":"10.1016\/j.talanta.2020.121110","article-title":"An electronic tongue for simultaneous determination of Ca2+, Mg2+, K+ and NH4+ in water samples by multivariate calibration methods","volume":"217","author":"Atas","year":"2020","journal-title":"Talanta"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"6019","DOI":"10.1039\/C7AY01756A","article-title":"Monitoring of drinking water quality: A preliminary approach by an electronic tongue based on functionalized polymer membrane electrodes","volume":"9","author":"Mahato","year":"2017","journal-title":"Anal. Methods-Uk"},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Gutierrez-Capitan, M., Brull-Fontsere, M., and Jimenez-Jorquera, C. (2019). Organoleptic Analysis of Drinking Water Using an Electronic Tongue Based on Electrochemical Microsensors. Sensors, 19.","DOI":"10.3390\/s19061435"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1002\/(SICI)1521-4109(199907)11:10\/11<814::AID-ELAN814>3.0.CO;2-7","article-title":"Application of electronic tongue for quantitative analysis of mineral water and wine","volume":"11","author":"Legin","year":"1999","journal-title":"Electroanalysis"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1007\/s00216-006-0530-2","article-title":"A sequential injection electronic tongue employing the transient response from potentiometric sensors for anion multidetermination","volume":"385","author":"Cortina","year":"2006","journal-title":"Anal. Bioanal. Chem."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1002\/elan.200603763","article-title":"Automated SIA system using an array of potentiometric sensors for determining alkaline-earth ions in water","volume":"19","author":"Calvo","year":"2007","journal-title":"Electroanalysis"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s00604-007-0894-9","article-title":"Electronic tongue for the determination of alkaline ions using a screen-printed potentiometric sensor array","volume":"163","author":"Gutierrez","year":"2008","journal-title":"Mikrochim. Acta"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.snb.2005.12.063","article-title":"Multi-sensor array used as an \u201celectronic tongue\u201d for mineral water analysis","volume":"116","author":"Moreno","year":"2006","journal-title":"Sens. Actuators B-Chem."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.snb.2004.05.022","article-title":"An \u201celectronic tongue\u201d design for the qualitative analysis of natural waters","volume":"104","author":"Soto","year":"2005","journal-title":"Sens. Actuators B-Chem."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.sna.2011.09.039","article-title":"A comparison study of pattern recognition algorithms implemented on a microcontroller for use in an electronic tongue for monitoring drinking waters","volume":"172","author":"Atkinson","year":"2011","journal-title":"Sens. Actuators A-Phys"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"3511","DOI":"10.1039\/D1AY00956G","article-title":"Inexpensive ion-selective electrodes for the simultaneous monitoring of potassium and nitrate concentrations in nutrient solutions","volume":"13","author":"Miras","year":"2021","journal-title":"Anal. Methods-UK"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1016\/j.talanta.2011.07.027","article-title":"Benzodipyrrole derivates as new ionophores for anion-selective electrodes: Improving potentiometric selectivity towards divalent anions","volume":"85","author":"Cuartero","year":"2011","journal-title":"Talanta"},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Gonzalez-Franco, J.A., Ruiz, A., and Ortuno, J.A. (2022). Dynamic Potentiometry with an Ion-Selective Electrode: A Tool for Qualitative and Quantitative Analysis of Inorganic and Organic Cations. Chemosensors, 10.","DOI":"10.3390\/chemosensors10030116"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1002\/elan.201400586","article-title":"New Potentiometric Electronic Tongue for Analysing Teas and Infusions","volume":"27","author":"Cuartero","year":"2015","journal-title":"Electroanalysis"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1213\/ANE.0000000000002864","article-title":"Correlation Coefficients: Appropriate Use and Interpretation","volume":"126","author":"Schober","year":"2018","journal-title":"Anesth. 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