{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T07:50:20Z","timestamp":1776153020379,"version":"3.50.1"},"reference-count":49,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2022,10,30]],"date-time":"2022-10-30T00:00:00Z","timestamp":1667088000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"DAAD Research Stays for University Academics and Scientists","award":["7442043"],"award-info":[{"award-number":["7442043"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Monitoring disease progression in Parkinson\u2019s disease is challenging. Postural transfers by sit-to-stand motions are adapted to trace the motor performance of subjects. Wearable sensors such as inertial measurement units allow for monitoring motion performance. We propose quantifying the sit-to-stand performance based on two scores compiling kinematics, dynamics, and energy-related variables. Three groups participated in this research: asymptomatic young participants (n = 33), senior asymptomatic participants (n = 17), and Parkinson\u2019s patients (n = 20). An unsupervised classification was performed of the two scores to differentiate the three populations. We found a sensitivity of 0.4 and a specificity of 0.96 to distinguish Parkinson\u2019s patients from asymptomatic subjects. In addition, seven Parkinson\u2019s patients performed the sit-to-stand task \u201cON\u201d and \u201cOFF\u201d medication, and we noted the scores improved with the patients\u2019 medication states (MDS-UPDRS III scores). Our investigation revealed that Parkinson\u2019s patients demonstrate a wide spectrum of mobility variations, and while one inertial measurement unit can quantify the sit-to-stand performance, differentiating between PD patients and healthy adults and distinguishing between \u201cON\u201d and \u201cOFF\u201d periods in PD patients is still challenging.<\/jats:p>","DOI":"10.3390\/s22218340","type":"journal-article","created":{"date-parts":[[2022,10,30]],"date-time":"2022-10-30T10:47:57Z","timestamp":1667126877000},"page":"8340","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Scoring the Sit-to-Stand Performance of Parkinson\u2019s Patients with a Single Wearable Sensor"],"prefix":"10.3390","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0440-4849","authenticated-orcid":false,"given":"Fr\u00e9d\u00e9ric","family":"Marin","sequence":"first","affiliation":[{"name":"Laboratoire de BioM\u00e9canique et BioIng\u00e9nierie (UMR CNRS 7338), Centre of Excellence for Human and Animal Movement Biomechanics (CoEMoB), Universit\u00e9 de Technologie de Compi\u00e8gne (UTC), Alliance Sorbonne Universit\u00e9, 60200 Compi\u00e8gne, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2343-7761","authenticated-orcid":false,"given":"Elke","family":"Warmerdam","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kiel University, 24105 Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zo\u00e9","family":"Marin","sequence":"additional","affiliation":[{"name":"Faculty of Computer Science or Communication Systems, Ecole Polytechnique F\u00e9d\u00e9rale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalil","family":"Ben Mansour","sequence":"additional","affiliation":[{"name":"Laboratoire de BioM\u00e9canique et BioIng\u00e9nierie (UMR CNRS 7338), Centre of Excellence for Human and Animal Movement Biomechanics (CoEMoB), Universit\u00e9 de Technologie de Compi\u00e8gne (UTC), Alliance Sorbonne Universit\u00e9, 60200 Compi\u00e8gne, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5945-4694","authenticated-orcid":false,"given":"Walter","family":"Maetzler","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kiel University, 24105 Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4813-3868","authenticated-orcid":false,"given":"Clint","family":"Hansen","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kiel University, 24105 Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.neurol.2015.09.012","article-title":"Epidemiology of Parkinson\u2019s Disease","volume":"172","author":"Elbaz","year":"2016","journal-title":"Rev. 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