{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T10:00:13Z","timestamp":1780912813881,"version":"3.54.1"},"reference-count":31,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2022,12,16]],"date-time":"2022-12-16T00:00:00Z","timestamp":1671148800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Heinz und Anneliese Medaljon-Foundation","award":["133\/19"],"award-info":[{"award-number":["133\/19"]}]},{"name":"Open Access Publication Fund of the University of Duisburg-Essen","award":["133\/19"],"award-info":[{"award-number":["133\/19"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Robot-assisted gait training (RAGT) provides a task-based support of walking using exoskeletons. Evidence shows moderate, but positive effects in the therapy of patients with cerebral palsy (CP). This study investigates the impact of RAGT on walking speed and gait parameters in pediatric CP patients. Thirty subjects (male = 23; female = 7), with a mean age of 13.0 \u00b1 2.5 (9\u201317) years, and with spastic CP, were recruited. The intervention group (n = 15) underwent six 20-minute RAGT sessions with the Hybrid Assistive Limb (HAL) during an 11-day hospital stay. Additionally, a therapy concept including physiotherapy, physician-performed manual medicine, massage and exercise therapy was provided. The control group (n = 15) was treated with the therapy concept only. The outcome was based on a 10-Metre Walking Test (10MWT), 6-Minute Walking Test (6MWT), Gross Motor Function Measure (GMFM-88) and lower extremities passive range of motion. The intervention group achieved a mean increase in walking speed in the 10MWT (self-selected walking speed SSW) of 5.5 s (p = 0.378). There were no significant differences between the groups in the 10MWT (max) (p = 0.123) and the 6MWT (p = 0.8). Changes in the GMFM (total) and in the dimension standing and walking, running and jumping (D + E) showed clinically relevant significant results (p = 0.002 and p = 0.046). RAGT as a supplement to an inpatient therapy stay appears to have a positive, yet not significant impact on the gait parameters of pediatric CP patients as well as motivating them to practice walking. Further studies with adapted study designs are needed to evaluate different influencing factors.<\/jats:p>","DOI":"10.3390\/s22249946","type":"journal-article","created":{"date-parts":[[2022,12,19]],"date-time":"2022-12-19T09:31:01Z","timestamp":1671442261000},"page":"9946","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Use of Robot-Assisted Gait Training in Pediatric Patients with Cerebral Palsy in an Inpatient Setting\u2014A Randomized Controlled Trial"],"prefix":"10.3390","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7759-0075","authenticated-orcid":false,"given":"Fabian","family":"Moll","sequence":"first","affiliation":[{"name":"Klinik f\u00fcr Manuelle Therapie (Hospital for Pain Management), Ostenalle 83, 59071 Hamm, Germany"},{"name":"Department for Trauma-, Hand- and Reconstructive Surgery, University Hospital Essen, University of Duisburg-Essen, Hufelandstra\u00dfe 55, 45147 Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axel","family":"Kessel","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Manuelle Therapie (Hospital for Pain Management), Ostenalle 83, 59071 Hamm, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Bonetto","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Manuelle Therapie (Hospital for Pain Management), Ostenalle 83, 59071 Hamm, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna","family":"Stresow","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Manuelle Therapie (Hospital for Pain Management), Ostenalle 83, 59071 Hamm, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9697-0287","authenticated-orcid":false,"given":"Monika","family":"Herten","sequence":"additional","affiliation":[{"name":"Department for Trauma-, Hand- and Reconstructive Surgery, University Hospital Essen, University of Duisburg-Essen, Hufelandstra\u00dfe 55, 45147 Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6641-5506","authenticated-orcid":false,"given":"Marcel","family":"Dudda","sequence":"additional","affiliation":[{"name":"Department for Trauma-, Hand- and Reconstructive Surgery, University Hospital Essen, University of Duisburg-Essen, Hufelandstra\u00dfe 55, 45147 Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Adermann","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Manuelle Therapie (Hospital for Pain Management), Ostenalle 83, 59071 Hamm, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1111\/dmcn.12080","article-title":"An Update on the Prevalence of Cerebral Palsy: A Systematic Review and Meta-Analysis","volume":"55","author":"Oskoui","year":"2013","journal-title":"Dev. 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