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Technology Department of Jiangxi Province","award":["20184006"],"award-info":[{"award-number":["20184006"]}]},{"name":"Science and Technology Department of Jiangxi Province","award":["20212BAG70033"],"award-info":[{"award-number":["20212BAG70033"]}]},{"name":"Science and Technology Department of Jiangxi Province","award":["20181BBG78063"],"award-info":[{"award-number":["20181BBG78063"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>The purpose of this study is to quantitatively evaluate the differences in corneal biomechanics after SMILE and FLEx surgery using an acoustic radiation force optical coherence elastography system (ARF-OCE) and to analyze the effect of the corneal cap on the integrity of corneal biomechanical properties. A custom ring array ultrasound transducer is used to excite corneal tissue to produce Lamb waves. Depth-resolved elastic modulus images of the in vivo cornea after refractive surgery were obtained based on the phase velocity of the Lamb wave. After refractive surgery, the average elastic modulus of the corneal flap decreased (71.7 \u00b1 24.6 kPa), while the elastic modulus of the corneal cap increased (219.5 \u00b1 54.9 kPa). The average elastic modulus of residual stromal bed (RSB) was increased after surgery, and the value after FLEx (305.8 \u00b1 48.5 kPa) was significantly higher than that of SMILE (221.3 \u00b1 43.2 kPa). Compared with FLEx, SMILE preserved most of the anterior stroma with less change in corneal biomechanics, which indicated that SMILE has an advantage in preserving the integrity of the corneal biomechanical properties. Therefore, the biomechanical properties of the cornea obtained by the ARF-OCE system may be one of the essential indicators for evaluating the safety of refractive surgery.<\/jats:p>","DOI":"10.3390\/s23010181","type":"journal-article","created":{"date-parts":[[2022,12,27]],"date-time":"2022-12-27T02:55:07Z","timestamp":1672109707000},"page":"181","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Quantitative Evaluation of In Vivo Corneal Biomechanical Properties after SMILE and FLEx Surgery by Acoustic Radiation Force Optical Coherence Elastography"],"prefix":"10.3390","volume":"23","author":[{"given":"Yanzhi","family":"Zhao","sequence":"first","affiliation":[{"name":"School of Medical, Nanchang University, Nanchang 330031, China"},{"name":"Department of Ophthalmology, The Third Affiliated Hospital of Nanchang University, Nanchang 330008, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yirui","family":"Zhu","sequence":"additional","affiliation":[{"name":"School of Physics, Nanjing University, Nanjing 210093, China"},{"name":"Key Laboratory of Opto-Electronic Information Science and Technology of Jiangxi Province, Jiangxi Engineering Laboratory for Optoelectronics Testing Technology, Nanchang Hangkong University, Nanchang 330063, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongbo","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Medical, Nanchang University, Nanchang 330031, China"},{"name":"Department of Ophthalmology, The Third Affiliated Hospital of Nanchang University, Nanchang 330008, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongwei","family":"Yang","sequence":"additional","affiliation":[{"name":"School of Medical, Nanchang University, Nanchang 330031, China"},{"name":"Department of Ophthalmology, The Third Affiliated Hospital of Nanchang University, Nanchang 330008, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingdao","family":"He","sequence":"additional","affiliation":[{"name":"Key Laboratory of Opto-Electronic Information Science and Technology of Jiangxi Province, Jiangxi Engineering Laboratory for Optoelectronics Testing Technology, Nanchang Hangkong University, Nanchang 330063, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1971-7402","authenticated-orcid":false,"given":"Tomas Gomez","family":"Alvarez-Arenas","sequence":"additional","affiliation":[{"name":"Institute for Physical and Information Technologies, Spanish National Research Council, Serrano 144, 28006 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingjie","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, The Third Affiliated Hospital of Nanchang University, Nanchang 330008, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guofu","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Medical, Nanchang University, Nanchang 330031, China"},{"name":"Department of Ophthalmology, The Third Affiliated Hospital of Nanchang University, Nanchang 330008, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"8","DOI":"10.3928\/1081-597X-20030101-03","article-title":"Femtosecond laser flap creation for laser in situ keratomileusis: Six-month follow-up of initial U.S. clinical series","volume":"19","author":"Nordan","year":"2003","journal-title":"J. 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