{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T04:27:37Z","timestamp":1772080057928,"version":"3.50.1"},"reference-count":18,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,12,27]],"date-time":"2022-12-27T00:00:00Z","timestamp":1672099200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Japan Science and Technology Agency (JST)","award":["JPMJTM19AN"],"award-info":[{"award-number":["JPMJTM19AN"]}]},{"name":"Piezo Parts Co., Ltd.","award":["JPMJTM19AN"],"award-info":[{"award-number":["JPMJTM19AN"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Quartz-crystal microbalance (QCM) is a technique that can measure nanogram-order masses. When a receptor is immobilized on the sensor surface of a QCM device, the device can detect chemical molecules captured by the mass change. Although QCM devices have been applied to biosensors that detect biomolecules without labels for biomolecular interaction analysis, most highly sensitive QCM devices are benchtop devices. We considered the fabrication of an IC card-sized QCM device that is both portable and battery-powered. Its miniaturization was achieved by repurposing electronic components and film batteries from smartphones and wearable devices. To demonstrate the applicability of the card-sized QCM device as a biosensor, DNA-detection experiments were performed. The card-sized QCM device could detect specific 10-mer DNA chains while discerning single-base differences with a sensitivity similar to that of a conventional benchtop device. The card-sized QCM device can be used in laboratories and in various other fields as a mass sensor.<\/jats:p>","DOI":"10.3390\/s23010281","type":"journal-article","created":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T05:31:54Z","timestamp":1672205514000},"page":"281","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Pocketable Biosensor Based on Quartz-Crystal Microbalance and Its Application to DNA Detection"],"prefix":"10.3390","volume":"23","author":[{"given":"Hiroshi","family":"Yoshimine","sequence":"first","affiliation":[{"name":"Graduate School of Science and Engineering, Yamagata University, Yonezawa 992-8510, Japan"}]},{"given":"Kai","family":"Sasaki","sequence":"additional","affiliation":[{"name":"Graduate School of Science and Engineering, Yamagata University, Yonezawa 992-8510, Japan"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5181-7828","authenticated-orcid":false,"given":"Hiroyuki","family":"Furusawa","sequence":"additional","affiliation":[{"name":"Graduate School of Science and Engineering, Yamagata University, Yonezawa 992-8510, Japan"},{"name":"Institute for the Promotion of General Graduate Education (IPGE), Yamagata University, Yonezawa 992-8510, Japan"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"70","DOI":"10.3390\/bios1030070","article-title":"Review of transducer principles for label-free biomolecular interaction analysis","volume":"1","author":"Nirschl","year":"2011","journal-title":"Biosensors"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Wang, D., Loo, J.F.C., Chen, J., Yam, Y., Chen, S.C., He, H., Kong, S.K., and Ho, H.P. 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