{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T06:27:11Z","timestamp":1775629631950,"version":"3.50.1"},"reference-count":33,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,1,12]],"date-time":"2023-01-12T00:00:00Z","timestamp":1673481600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Recent advances in mobile technology have shown that augmented unisensory feedback can be leveraged to improve gait using wearable systems, but less is known about the possible benefits and usability of multisensory (i.e., multimodal) feedback. This paper introduces the preliminary results of an innovative research project aiming to develop an mHealth system including Android smart glasses, and providing multisensory cues for gait rehabilitation of people affected by Parkinson\u2019s disease in and out of the medical context. In particular, the paper describes a preliminary pilot focusing on the design of visual, auditory, and haptic cues, and testing the design methodologies to be used in further developments of the project. Considered research questions were: Which kinds of images, sounds, and vibrations mostly influence gait speed, stride length, and cadence? Which are the ones stressing the user the least? Which ones induce the most immediate reaction? Thus, in this starting part of the research project, different typologies of sensory cues were designed, tested, and evaluated considering quantitative and qualitative parameters to properly answer the research questions.<\/jats:p>","DOI":"10.3390\/s23020874","type":"journal-article","created":{"date-parts":[[2023,1,12]],"date-time":"2023-01-12T04:29:38Z","timestamp":1673497778000},"page":"874","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Multisensory Cues for Gait Rehabilitation with Smart Glasses: Methodology, Design, and Results of a Preliminary Pilot"],"prefix":"10.3390","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8611-0045","authenticated-orcid":false,"given":"Silvia","family":"Imbesi","sequence":"first","affiliation":[{"name":"Department of Architecture, University of Ferrara, 44121 Ferrara, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5010-6116","authenticated-orcid":false,"given":"Mattia","family":"Corzani","sequence":"additional","affiliation":[{"name":"Department of Electrical, Electronic, and Information Engineering, University of Bologna, 40126 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Meara, J., and Koller, W.C. (2000). Parkinson\u2019s Disease and Parkinsonism in the Elderly, Cambridge University Press.","DOI":"10.1017\/CBO9780511585012"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/s10072-010-0228-2","article-title":"Three-dimensional motion analysis of the effects of auditory cueing on gait pattern in patients with Parkinson\u2019s disease: A preliminary investigation","volume":"31","author":"Picelli","year":"2010","journal-title":"Neurol. Sci."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.apmr.2012.10.026","article-title":"Cueing and gait improvement among people with Parkinson\u2019s disease: A meta-analysis","volume":"94","author":"Spaulding","year":"2013","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"e5004","DOI":"10.1136\/bmj.e5004","article-title":"Physiotherapy intervention in Parkinson\u2019s disease: Systematic review and meta-analysis","volume":"345","author":"Tomlinson","year":"2012","journal-title":"BMJ"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/S1474-4422(13)70123-6","article-title":"Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson\u2019s disease","volume":"12","author":"Petzinger","year":"2013","journal-title":"Lancet Neurol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1136\/jnnp.200X.097923","article-title":"Cueing training in the home improves gait-related mobility in Parkinson\u2019s disease: The RESCUE trial","volume":"78","author":"Nieuwboer","year":"2007","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.brainres.2010.01.001","article-title":"Evidence for motor learning in Parkinson\u2019s disease: Acquisition, automaticity and retention of cued gait performance after training with external rhythmical cues","volume":"1319","author":"Rochester","year":"2010","journal-title":"Brain Res."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.clineuro.2014.06.026","article-title":"Effects of external cues on gait parameters of Parkinson\u2019s disease patients: A systematic review","volume":"124","author":"Rocha","year":"2014","journal-title":"Clin. Neurol. Neurosurg."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Cassenti, D.N., Scataglini, S., Rajulu, S.L., and Wright, J.L. (2021). How to Enhance Aging People\u2019s Wellness by Means of Human Centered and Co-design Methodology. Advances in Simulation and Digital Human Modeling, Proceedings of the AHFE 2020 Virtual Conferences on Human Factors and Simulation, and Digital Human Modeling and Applied Optimization, USA, 16\u201320 July 2020, Springer International Publishing.","DOI":"10.1007\/978-3-030-51064-0"},{"key":"ref_10","unstructured":"Stoker, T.B., and Greenland, J.C. (2018). Parkinson\u2019s Disease: Etiology, Neuropathology, and Pathogenesis. Parkinson\u2019s Disease: Pathogenesis and Clinical Aspects, Codon Publications."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1007\/s11517-021-02365-3","article-title":"Vibrotactile biofeedback devices in Parkinson\u2019s disease: A narrative review","volume":"59","author":"Rodrigues","year":"2021","journal-title":"Med. Biol. Eng. Comput."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1109\/TNSRE.2017.2762239","article-title":"The Effects of Coding Schemes on Vibrotactile Biofeedback for Dynamic Balance Training in Parkinson\u2019s Disease and Healthy Elderly Individuals","volume":"26","author":"Lee","year":"2018","journal-title":"IEEE Trans. Neural Syst. Rehabil. Eng."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.2522\/ptj.20050277","article-title":"Locomotor training in people with Parkinson disease","volume":"86","author":"Morris","year":"2006","journal-title":"Phys. Ther."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.neubiorev.2018.05.007","article-title":"Basal ganglia and beyond: The interplay between motor and cognitive aspects in Parkinson\u2019s disease rehabilitation","volume":"90","author":"Ferrazzoli","year":"2018","journal-title":"Neurosci. Biobehav. Rev."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1038\/nrn2915","article-title":"Goal-directed and habitual control in the basal ganglia: Implications for Parkinson\u2019s disease","volume":"11","author":"Redgrave","year":"2010","journal-title":"Nat. Rev. Neurosci."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1191\/0269215505cr906oa","article-title":"Effects of external rhythmical cueing on gait in patients with Parkinson\u2019s disease: A systematic review","volume":"19","author":"Lim","year":"2005","journal-title":"Clin. Rehabil."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"255","DOI":"10.3389\/fneur.2015.00255","article-title":"Cues and Attention in Parkinsonian Gait: Potential Mechanisms and Future Directions","volume":"6","author":"Peterson","year":"2015","journal-title":"Front. Neurol."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Gon\u00e7alves, H., Minas, G., Rodrigues, A., and Santos, C. (2017, January 26\u201328). Literature review of vibrotactile systems addressing freezing of gait in parkinsonians. Proceedings of the 2017 IEEE International Conference on Autonomous Robot Systems and Competitions (ICARSC), Coimbra, Portugal.","DOI":"10.1109\/ICARSC.2017.7964060"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1016\/j.visres.2004.11.006","article-title":"Visual and spatial symptoms in Parkinson\u2019s disease","volume":"45","author":"Davidsdottir","year":"2005","journal-title":"Vis. Res."},{"key":"ref_20","first-page":"157","article-title":"Time to port augmented reality health apps to smart glasses? Cyberpsychology Behav","volume":"16","author":"Wiederhold","year":"2013","journal-title":"Soc. Netw."},{"key":"ref_21","unstructured":"McNaney, R., Vines, J., Roggen, D., Balaam, M., Zhang, P., Poliakov, I., and Olivier, P. (May, January 26). Exploring the acceptability of google glass as an everyday assistive device for people with Parkinson\u2019s. Proceedings of the SIGCHI Conference on Human Factors in Computing Systems, Toronto, ON, Canada."},{"key":"ref_22","unstructured":"(2022, October 01). Vuzix Blade\u00ae Upgraded Version. Available online: https:\/\/www.vuzix.com\/products\/blade-smart-glasses-upgraded."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"6229","DOI":"10.3390\/s140406229","article-title":"A wearable system for gait training in subjects with Parkinson\u2019s disease","volume":"14","author":"Casamassima","year":"2014","journal-title":"Sensors"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1152\/physiol.00034.2015","article-title":"Neural Control of Walking in People with Parkinsonism","volume":"31","author":"Peterson","year":"2016","journal-title":"Physiology"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1080\/08990220.2017.1421157","article-title":"Comparing auditory, visual and vibrotactile cues in individuals with Parkinson\u2019s disease for reducing risk of falling over different types of soil","volume":"34","author":"Ayena","year":"2017","journal-title":"Somatosens. Mot. Res."},{"key":"ref_26","unstructured":"mHealth Technologies (2022, October 01). Assessment\u2014mTEST3. Available online: http:\/\/mhealthtechnologies.it\/products-wearable-sensors-smartphone-apps\/assessment-mtest3\/."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1136\/bjsports-2017-097628","article-title":"How fast is fast enough? Walking cadence (steps\/min) as a practical estimate of intensity in adults: A narrative review","volume":"52","author":"Han","year":"2018","journal-title":"Br. J. Sport. Med."},{"key":"ref_28","unstructured":"Akao, Y., Mazur, G.H., and King, B. (1990). Quality Function Deployment: Integrating Customer Requirements into Product Design, Taylor & Francis."},{"key":"ref_29","unstructured":"Di Bucchianico, G. (2020). Collaborative Quality Function Deployment. A Methodology for Enabling Co-design Research Practice. Advances in Design for Inclusion, Proceedings of the AHFE 2019 International Conference on Design for Inclusion and the AHFE 2019 International Conference on Human Factors for Apparel and Textile Engineering, Washington, DC, USA, 24\u201328 July 2019, Springer International Publishing."},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Imbesi, S., and Scataglini, S. (2021). A User Centered Methodology for the Design of Smart Apparel for Older Users. Sensors, 21.","DOI":"10.3390\/s21082804"},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Di Bucchianico, G., and Kercher, P.F. (2018). Inclusive Design for Ageing People and the Internet of Things: Understanding Needs. Advances in Design for Inclusion, Proceedings of the AHFE 2017 International Conference on Design for Inclusion, Los Angeles, CA, USA, 17\u201321 July 2017, Springer International Publishing.","DOI":"10.1007\/978-3-319-60597-5"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3758\/s13423-012-0333-8","article-title":"Augmented visual, auditory, haptic, and multimodal feedback in motor learning: A review","volume":"20","author":"Sigrist","year":"2013","journal-title":"Psychon. Bull. Rev."},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Imbesi, S., Corzani, M., Lopane, G., Mincolelli, G., and Chiari, L. (2022). User-Centered Design Methodologies for the Prototype Development of a Smart Harness and Related System to Provide Haptic Cues to Persons with Parkinson\u2019s Disease. 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