{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T23:28:50Z","timestamp":1774308530011,"version":"3.50.1"},"reference-count":35,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T00:00:00Z","timestamp":1674172800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Auvergne-Rh\u00f4ne-Alpes region","award":["ANR-10-LABX-0075"],"award-info":[{"award-number":["ANR-10-LABX-0075"]}]},{"name":"LABEX MANUTECH-SISE","award":["ANR-10-LABX-0075"],"award-info":[{"award-number":["ANR-10-LABX-0075"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>A new plasmonic configuration is proposed for application in a sensor and demonstrated for the detection of variations in the bulk refractive index of solutions. The configuration consists of monitoring two diffracted orders resulting from the interaction of a TM-polarized optical beam incident on a grating coupler, operating based on an effect termed the \u201coptical switch\u201d. The two monitored diffracted orders enable differential measurements which cancel the drift and perturbations common to both, leading to an improved detection limit, as demonstrated experimentally. The measured switch pattern associated with the grating coupler is in good agreement with theory. Bulk sensing is demonstrated under intensity interrogation via the sequential injection of solutions comprised of glycerol in water into a fluidic cell. A limit of detection of about 10\u22126 RIU was achieved. The optical switch configuration is easy to implement and is cost-effective, yielding a highly promising approach for the sensing and the real-time detection of biological species.<\/jats:p>","DOI":"10.3390\/s23031188","type":"journal-article","created":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T02:35:55Z","timestamp":1674182155000},"page":"1188","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Differential Sensing with Replicated Plasmonic Gratings Interrogated in the Optical Switch Configuration"],"prefix":"10.3390","volume":"23","author":[{"given":"Emilie","family":"Laffont","sequence":"first","affiliation":[{"name":"School of Electrical Engineering and Computer Science, University of Ottawa, Ottawa, ON K1N 6N5, Canada"},{"name":"Department of Physics, University of Ottawa, Ottawa, ON K1N 6N5, Canada"},{"name":"Laboratoire Hubert Curien, Universit\u00e9 de Lyon, UMR CNRS 5516, 42000 Saint-Etienne, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Crespo-Monteiro","sequence":"additional","affiliation":[{"name":"Laboratoire Hubert Curien, Universit\u00e9 de Lyon, UMR CNRS 5516, 42000 Saint-Etienne, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1152-1277","authenticated-orcid":false,"given":"Arnaud","family":"Valour","sequence":"additional","affiliation":[{"name":"Laboratoire Hubert Curien, Universit\u00e9 de Lyon, UMR CNRS 5516, 42000 Saint-Etienne, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6795-7275","authenticated-orcid":false,"given":"Pierre","family":"Berini","sequence":"additional","affiliation":[{"name":"School of Electrical Engineering and Computer Science, University of Ottawa, Ottawa, ON K1N 6N5, Canada"},{"name":"Department of Physics, University of Ottawa, Ottawa, ON K1N 6N5, Canada"},{"name":"Nexus for Quantum Technologies Institute, Advanced Research Complex, 25 Templeton Street, Ottawa, ON K1N 6N5, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yves","family":"Jourlin","sequence":"additional","affiliation":[{"name":"Laboratoire Hubert Curien, Universit\u00e9 de Lyon, UMR CNRS 5516, 42000 Saint-Etienne, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"3655","DOI":"10.1021\/acssensors.0c01382","article-title":"On the challenges for the diagnosis of SARS-CoV-2 based on a review of current methodologies","volume":"5","author":"Mattioli","year":"2020","journal-title":"ACS Sens."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2000074","DOI":"10.1002\/adts.202000074","article-title":"Investigation of plasmonic detection of human respiratory virus","volume":"3","author":"Das","year":"2020","journal-title":"Adv. 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