{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:48:16Z","timestamp":1760147296889,"version":"build-2065373602"},"reference-count":19,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2023,1,24]],"date-time":"2023-01-24T00:00:00Z","timestamp":1674518400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"JSPS KAKENHI","award":["JP 21K03960"],"award-info":[{"award-number":["JP 21K03960"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>In order to advance engineering applications of robotics such as wearable health-monitoring devices, humanoid robots, etc., it is essential to investigate the tactile sensations of artificial haptic sensors mimicking bioinspired human cutaneous mechanoreceptors such as free nerve endings, Merkel\u2019s cells, Krause end bulbs, Meissner corpuscles, Ruffini endings, and Pacinian corpuscles. The generated receptor\u2019s potential response to extraneous stimuli, categorized as slow adaption (SA) or fast adaption (FA), is particularly significant as a typical property. The present study addressed the estimation of SA and FA by utilizing morphologically fabricated mechanoreceptors made of our proposed magnetically responsive intelligent fluid, hybrid fluid (HF), and by applying our proposed electrolytic polymerization. Electric circuit models of the mechanoreceptors were generated using experimental data on capacitance and inductance on the basis of the electric characteristics of impedance. The present results regarding equivalent firing rates based on FA and SA are consistent with the FA and SA findings of vital mechanoreceptors by biomedical analysis. The present investigative process is useful to clarify the time of response to a force on the fabricated artificial mechanoreceptor.<\/jats:p>","DOI":"10.3390\/s23031327","type":"journal-article","created":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T03:23:49Z","timestamp":1674617029000},"page":"1327","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Estimation of Fast and Slow Adaptions in the Tactile Sensation of Mechanoreceptors Mimicked by Hybrid Fluid (HF) Rubber with Equivalent Electric Circuits and Properties"],"prefix":"10.3390","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9174-503X","authenticated-orcid":false,"given":"Kunio","family":"Shimada","sequence":"first","affiliation":[{"name":"Faculty of Symbiotic Systems Sciences, Fukushima University, 1 Kanayagawa, Fukushima 960-1296, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"eaar7650","DOI":"10.1126\/scirobotics.aar7650","article-title":"The grand challenges of science robotics","volume":"3","author":"Yang","year":"2018","journal-title":"Sci. Robot."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2107902","DOI":"10.1002\/adma.202107902","article-title":"Flexible electronics and devices as human-machine interfaces for medical robotics","volume":"34","author":"Heng","year":"2022","journal-title":"Adv. Mater."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1803637","DOI":"10.1002\/adma.201803637","article-title":"Bioinspired electronics for artificial sensory systems","volume":"31","author":"Jung","year":"2019","journal-title":"Adv. Mater."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"11182","DOI":"10.1002\/anie.201813402","article-title":"Bio-inspired design and additive manufacturing of soft materials, machines, robots, and haptic interfaces","volume":"58","author":"Li","year":"2019","journal-title":"Angew. Chem. Int. Ed."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1904765","DOI":"10.1002\/adma.201904765","article-title":"Electronic skin: Recent progress and future prospects for skin-attachable devices for health monitoring, robotics, and prosthetics","volume":"31","author":"Yang","year":"2019","journal-title":"Adv. Mater."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1038\/nmat4671","article-title":"Pursuing prosthetic electronic skin","volume":"15","author":"Chortos","year":"2016","journal-title":"Nat. Mater."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1679\/aohc.51.1","article-title":"The structure and function of cutaneous sensory receptors","volume":"51","author":"Munger","year":"1988","journal-title":"Arch. Histol. Cytol."},{"key":"ref_8","unstructured":"Squire, L.R. (2009). Encyclopedia of Neuroscience, Elsevier."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/0079-6107(95)00011-9","article-title":"Mammalian cutaneous mechanoreceptors","volume":"64","author":"Hamann","year":"1995","journal-title":"Prog. Biophys. Mol. Biol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1121\/1.397184","article-title":"Four channels mediate the mechanical aspects of touch","volume":"84","author":"Bolanowski","year":"1988","journal-title":"J. Acoust. Soc. Am."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1706299","DOI":"10.1002\/adma.201706299","article-title":"A self-powered sensor mimicking slow- and fast-adapting cutaneous mechanoreceptors","volume":"30","author":"Chun","year":"2018","journal-title":"Adv. Mater."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Shimada, K. (2022). Morphological conFigureuration of sensory biomedical receptors based on structures integrated by electric circuits and utilizing magnetic-responsive hybrid fluid (HF). Sensors, 22.","DOI":"10.3390\/s22249952"},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Shimada, K., Ikeda, R., Kikura, H., and Takahashi, H. (2021). Morphological fabrication of rubber cutaneous receptors embedded in a stretchable skin-mimicking human tissue by the utilization of hybrid fluid. Sensors, 21.","DOI":"10.3390\/s21206834"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.molliq.2015.04.020","article-title":"AC and DC electrical conductivity in natural rubber\/nanofibrillated cellulose nanocomposites","volume":"209","author":"Ladhar","year":"2015","journal-title":"J. Mol. Liq."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.jnoncrysol.2013.06.018","article-title":"Dielectric relaxation studies on nanocomposites of rubber with nanofibrillated cellulose","volume":"378","author":"Ladhar","year":"2013","journal-title":"J. Non-Crys. Solids"},{"key":"ref_16","first-page":"2100352","article-title":"Engineered mechanosensors inspired by biological mechanosensilla","volume":"6","author":"Wang","year":"2021","journal-title":"Adv. Mater."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.sna.2012.02.051","article-title":"A review of tactile sensing technologies with applications in biomedical engineering","volume":"179","author":"Tiwana","year":"2012","journal-title":"Sens. Actuators A Phys."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"103980","DOI":"10.1016\/j.biosystems.2019.103980","article-title":"Review: Methods of firing rate estimation","volume":"183","author":"Tomar","year":"2019","journal-title":"BioSystems"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"322","DOI":"10.3389\/fnins.2018.00322","article-title":"A digital hardware realization for spiking model of cutaneous mechanoreceptor","volume":"12","author":"Nezhad","year":"2018","journal-title":"Fron. Neuro."}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/23\/3\/1327\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T18:15:00Z","timestamp":1760120100000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/23\/3\/1327"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,24]]},"references-count":19,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2023,2]]}},"alternative-id":["s23031327"],"URL":"https:\/\/doi.org\/10.3390\/s23031327","relation":{},"ISSN":["1424-8220"],"issn-type":[{"type":"electronic","value":"1424-8220"}],"subject":[],"published":{"date-parts":[[2023,1,24]]}}}