{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T05:18:58Z","timestamp":1783660738137,"version":"3.55.0"},"reference-count":46,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T00:00:00Z","timestamp":1674604800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31772068"],"award-info":[{"award-number":["31772068"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31872909"],"award-info":[{"award-number":["31872909"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32001781"],"award-info":[{"award-number":["32001781"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["ZR2020QC249"],"award-info":[{"award-number":["ZR2020QC249"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Shandong Provincial Natural Science Foundation","award":["31772068"],"award-info":[{"award-number":["31772068"]}]},{"name":"Shandong Provincial Natural Science Foundation","award":["31872909"],"award-info":[{"award-number":["31872909"]}]},{"name":"Shandong Provincial Natural Science Foundation","award":["32001781"],"award-info":[{"award-number":["32001781"]}]},{"name":"Shandong Provincial Natural Science Foundation","award":["ZR2020QC249"],"award-info":[{"award-number":["ZR2020QC249"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>In view of the great threat of chloramphenicol (CAP) to human health and the fact that a few producers have illegally used CAP in the food production process to seek economic benefits in disregard of laws and regulations and consumer health, we urgently need a detection method with convenient operation, rapid response, and high sensitivity capabilities to detect CAP in food to ensure people\u2019s health. Herein, a molecularly imprinted polymer (MIP) electrochemical sensor based on a dual-signal strategy was designed for the highly sensitive analysis of CAP in milk. The NiFe Prussian blue analog (NiFe-PBA) and SnS2 nanoflowers were modified successively on the electrode surface to obtain dual signals from [Fe(CN)6]3\u2212\/4\u2212 at 0.2 V and NiFe-PBA at 0.5 V. SiO2-COOH@MIPs that could specifically recognize CAP were synthesized via thermal polymerization using carboxylated silica microspheres (SiO2-COOH) as carriers. When the CAP was adsorbed by SiO2-COOH@MIPs, the above two oxidation peak currents decreased at the same time, allowing the double-signal analysis. The SiO2-COOH@MIPs\/SnS2\/NiFe-PBA\/GCE sensor used for determining CAP was successfully prepared. The sensor utilized the interactions of various nanomaterials to achieve high-sensitivity dual-signal detection, which had certain innovative significance. At the same time, the MIPs were synthesized using a surface molecular imprinting technology, which could omit the time of polymerization and elution and met the requirements for rapid detection. After optimizing the experimental conditions, the detection range of the sensor was 10\u22128 g\/L\u201310\u22122 g\/L and the limit of detection reached 3.3 \u00d7 10\u22129 g\/L (S\/N = 3). The sensor had satisfactory specificity, reproducibility, and stability, and was successfully applied to the detection of real milk samples.<\/jats:p>","DOI":"10.3390\/s23031346","type":"journal-article","created":{"date-parts":[[2023,1,26]],"date-time":"2023-01-26T01:30:30Z","timestamp":1674696630000},"page":"1346","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Novel Dual-Signal SiO2-COOH@MIPs Electrochemical Sensor for Highly Sensitive Detection of Chloramphenicol in Milk"],"prefix":"10.3390","volume":"23","author":[{"given":"Lingjun","family":"Geng","sequence":"first","affiliation":[{"name":"School of Agricultural Engineering and Food Science, Shandong University of Technology, No. 266 Xincun Xilu, Zibo 255049, China"},{"name":"Shandong Provincial Engineering Research Center of Vegetable Safety and Quality Traceability, No. 266 Xincun Xilu, Zibo 255049, China"},{"name":"Zibo City Key Laboratory of Agricultural Product Safety Traceability, No. 266 Xincun Xilu, Zibo 255049, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengyue","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Agricultural Engineering and Food Science, Shandong University of Technology, No. 266 Xincun Xilu, Zibo 255049, China"},{"name":"Shandong Provincial Engineering Research Center of Vegetable Safety and Quality Traceability, No. 266 Xincun Xilu, Zibo 255049, China"},{"name":"Zibo City Key Laboratory of Agricultural Product Safety Traceability, No. 266 Xincun Xilu, Zibo 255049, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingcheng","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Agricultural Engineering and Food Science, Shandong University of Technology, No. 266 Xincun Xilu, Zibo 255049, China"},{"name":"Shandong Provincial Engineering Research Center of Vegetable Safety and Quality Traceability, No. 266 Xincun Xilu, Zibo 255049, China"},{"name":"Zibo City Key Laboratory of Agricultural Product Safety Traceability, No. 266 Xincun Xilu, Zibo 255049, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Falan","family":"Li","sequence":"additional","affiliation":[{"name":"School of Agricultural Engineering and Food Science, Shandong University of Technology, No. 266 Xincun Xilu, Zibo 255049, China"},{"name":"Shandong Provincial Engineering Research Center of Vegetable Safety and Quality Traceability, No. 266 Xincun Xilu, Zibo 255049, China"},{"name":"Zibo City Key Laboratory of Agricultural Product Safety Traceability, No. 266 Xincun Xilu, Zibo 255049, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1059-643X","authenticated-orcid":false,"given":"Yanyan","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Agricultural Engineering and Food Science, Shandong University of Technology, No. 266 Xincun Xilu, Zibo 255049, China"},{"name":"Shandong Provincial Engineering Research Center of Vegetable Safety and Quality Traceability, No. 266 Xincun Xilu, Zibo 255049, China"},{"name":"Zibo City Key Laboratory of Agricultural Product Safety Traceability, No. 266 Xincun Xilu, Zibo 255049, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yemin","family":"Guo","sequence":"additional","affiliation":[{"name":"School of Agricultural Engineering and Food Science, Shandong University of Technology, No. 266 Xincun Xilu, Zibo 255049, China"},{"name":"Shandong Provincial Engineering Research Center of Vegetable Safety and Quality Traceability, No. 266 Xincun Xilu, Zibo 255049, China"},{"name":"Zibo City Key Laboratory of Agricultural Product Safety Traceability, No. 266 Xincun Xilu, Zibo 255049, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Sun","sequence":"additional","affiliation":[{"name":"School of Agricultural Engineering and Food Science, Shandong University of Technology, No. 266 Xincun Xilu, Zibo 255049, China"},{"name":"Shandong Provincial Engineering Research Center of Vegetable Safety and Quality Traceability, No. 266 Xincun Xilu, Zibo 255049, China"},{"name":"Zibo City Key Laboratory of Agricultural Product Safety Traceability, No. 266 Xincun Xilu, Zibo 255049, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"132883","DOI":"10.1016\/j.chemosphere.2021.132883","article-title":"Photodegradation of chloramphenicol in micro-polluted water using a circulatory thin-layer inclined plate reactor","volume":"291","author":"Xiong","year":"2022","journal-title":"Chemosphere"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"122392","DOI":"10.1016\/j.jssc.2021.122392","article-title":"Ultrasonic assisted preparation of CoMoO4 nanoparticles modified electrochemical sensor for chloramphenicol determination","volume":"302","author":"Vinothkumar","year":"2021","journal-title":"J. Solid State Chem."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1007\/s42114-021-00377-z","article-title":"Synergistic effect of silver plasmon resonance and p-n heterojunction enhanced photoelectrochemical aptasensing platform for detecting chloramphenicol","volume":"5","author":"Wu","year":"2022","journal-title":"Adv. Compos. Hybrid Mater."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1007\/s00604-022-05377-4","article-title":"Fluorescence determination of chloramphenicol in milk powder using carbon dot decorated silver metal-organic frameworks","volume":"189","author":"Wang","year":"2022","journal-title":"Microchim. Acta"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"112843","DOI":"10.1016\/j.fct.2022.112843","article-title":"Electrochemical quantification of mancozeb through tungsten oxide\/reduced graphene oxide nanocomposite: A potential method for environmental remediation","volume":"161","author":"Buledi","year":"2022","journal-title":"Food Chem. Toxicol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"102","DOI":"10.2174\/1573411016999201006122740","article-title":"Current Perspective and Developments in Electrochemical Sensors Modified with Nanomaterials for Environmental and Pharmaceutical Analysis","volume":"18","author":"Buledi","year":"2022","journal-title":"Curr. Anal. Chem."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"113177","DOI":"10.1016\/j.fct.2022.113177","article-title":"Selective oxidation of amaranth dye in soft drinks through tin oxide decorated reduced graphene oxide nanocomposite based electrochemical sensor","volume":"165","author":"Buledi","year":"2022","journal-title":"Food Chem. Toxicol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"133660","DOI":"10.1016\/j.foodchem.2022.133660","article-title":"Ultrasensitive paper sensor for simultaneous detection of alpha-amanitin and beta-amanitin by the production of monoclonal antibodies","volume":"396","author":"Zhou","year":"2022","journal-title":"Food Chem."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1007\/s12274-016-1270-z","article-title":"Gold nanoparticle-based paper sensor for ultrasensitive and multiple detection of 32 (fluoro)quinolones by one monoclonal antibody","volume":"10","author":"Peng","year":"2016","journal-title":"Nano Res."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"108105","DOI":"10.1016\/j.bioelechem.2022.108105","article-title":"CRISPR-Cas12a-mediated label-free electrochemical aptamer-based sensor for SARS-CoV-2 antigen detection","volume":"146","author":"Liu","year":"2022","journal-title":"Bioelectrochemistry"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"143129","DOI":"10.1016\/j.scitotenv.2020.143129","article-title":"Recent advances in aptamer-based sensors for aminoglycoside antibiotics detection and their applications","volume":"762","author":"Yue","year":"2021","journal-title":"Sci. Total Environ."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"113658","DOI":"10.1016\/j.lwt.2022.113658","article-title":"Dual enzyme electrochemiluminescence sensor based on in situ synthesis of ZIF-67@AgNPs for the detection of IMP in fresh meat","volume":"165","author":"Wang","year":"2022","journal-title":"LWT"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"339797","DOI":"10.1016\/j.aca.2022.339797","article-title":"A molecularly imprinted electrochemical sensor based on surface imprinted polymerization and boric acid affinity for selective and sensitive detection of P-glycoproteins","volume":"1207","author":"Yang","year":"2022","journal-title":"Anal. Chim. Acta"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"108638","DOI":"10.1016\/j.foodcont.2021.108638","article-title":"A novel molecularly imprinted polymer composite based on polyaniline nanoparticles as sensitive sensors for parathion detection in the field","volume":"133","author":"Liang","year":"2022","journal-title":"Food Control"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"e00144","DOI":"10.1016\/j.teac.2021.e00144","article-title":"Molecularly imprinted polymer-carbon paste electrode (MIP-CPE)-based sensors for the sensitive detection of organic and inorganic environmental pollutants: A review","volume":"32","author":"Mostafiz","year":"2021","journal-title":"Trends Environ. Anal."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"102693","DOI":"10.1016\/j.cis.2022.102693","article-title":"Development of molecularly imprinted polymer based phase boundaries for sensors design (review)","volume":"305","author":"Ramanavicius","year":"2022","journal-title":"Adv. Colloid Interface Sci."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"31639","DOI":"10.1039\/D2RA05401A","article-title":"Fluorene intercalated graphene oxide based CoQ10 imprinted polymer composite as a selective platform for electrochemical sensing of CoQ10","volume":"12","author":"Soomro","year":"2022","journal-title":"RSC Adv."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"339884","DOI":"10.1016\/j.aca.2022.339884","article-title":"Antifouling ionic liquid doped molecularly imprinted polymer-based ratiometric electrochemical sensor for highly stable and selective detection of zearalenone","volume":"1210","author":"Hu","year":"2022","journal-title":"Anal. Chim. Acta"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"133760","DOI":"10.1016\/j.chemosphere.2022.133760","article-title":"Plant extract-based green fabrication of nickel ferrite (NiFe(2)O(4)) nanoparticles: An operative platform for non-enzymatic determination of pentachlorophenol","volume":"294","author":"Taqvi","year":"2022","journal-title":"Chemosphere"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"135170","DOI":"10.1016\/j.chemosphere.2022.135170","article-title":"Electrochemical monitoring of bisphenol-s through nanostructured tin oxide\/Nafion\/GCE: A solution to environmental pollution","volume":"303","author":"Memon","year":"2022","journal-title":"Chemosphere"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"135270","DOI":"10.1016\/j.chemosphere.2022.135270","article-title":"Facile Synthesis of NiO\/ZnO nanocomposite as an effective platform for electrochemical determination of carbamazepine","volume":"303","author":"Qambrani","year":"2022","journal-title":"Chemosphere"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"214497","DOI":"10.1016\/j.ccr.2022.214497","article-title":"Nanoheterostructures based on nanosized Prussian blue and its Analogues: Design, properties and applications","volume":"461","author":"Guari","year":"2022","journal-title":"Coord. Chem. Rev."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.ensm.2019.09.024","article-title":"Prussian blue, its analogues and their derived materials for electrochemical energy storage and conversion","volume":"25","author":"Chen","year":"2020","journal-title":"Energy Storage Mater."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"230884","DOI":"10.1016\/j.jpowsour.2021.230884","article-title":"CoFeP nanocube-arrays based on Prussian blue analogues for accelerated oxygen evolution electrocatalysis","volume":"520","author":"Xiong","year":"2022","journal-title":"J. Power Sources"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"131612","DOI":"10.1016\/j.snb.2022.131612","article-title":"Ultrasensitive gas sensor based on Pd\/SnS2\/SnO2 nanocomposites for rapid detection of H2","volume":"359","author":"Meng","year":"2022","journal-title":"Sensors Actuat. B-Chem."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.solener.2021.11.041","article-title":"Strategies and perspectives of tailored SnS2 photocatalyst for solar driven energy applications","volume":"231","author":"Sharma","year":"2022","journal-title":"Sol. Energy"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"130775","DOI":"10.1016\/j.snb.2021.130775","article-title":"Au-modified 3D SnS2 nano-flowers for low-temperature NO2 sensors","volume":"349","author":"Zhu","year":"2021","journal-title":"Sensors Actuat. B-Chem."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"111445","DOI":"10.1016\/j.bios.2019.111445","article-title":"Ni-Fe PBA hollow nanocubes as efficient electrode materials for highly sensitive detection of guanine and hydrogen peroxide in human whole saliva","volume":"141","author":"Niu","year":"2019","journal-title":"Biosens. Bioelectron."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"3999","DOI":"10.1021\/acsami.0c20067","article-title":"Highly Crystallized Prussian Blue with Enhanced Kinetics for Highly Efficient Sodium Storage","volume":"13","author":"Qin","year":"2021","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"105055","DOI":"10.1016\/j.reactfunctpolym.2021.105055","article-title":"Preparation and evaluation of magnetic graphene oxide molecularly imprinted polymers (MIPs-GO-Fe3O4@SiO2) for the analysis and separation of tripterine","volume":"169","author":"Chen","year":"2021","journal-title":"React. Funct. Polym."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"29998","DOI":"10.1039\/C9RA05782J","article-title":"Magnetic molecularly imprinted polymers for the detection of aminopyralid in milk using dispersive solid-phase extraction","volume":"9","author":"He","year":"2019","journal-title":"RSC Adv."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"122258","DOI":"10.1016\/j.talanta.2021.122258","article-title":"A simple, sensitive and efficient electrochemical platform based on carbon paste electrode modified with Fe3O4@MIP and graphene oxide for folic acid determination in different matrices","volume":"229","author":"Garcia","year":"2021","journal-title":"Talanta"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.jhazmat.2010.02.072","article-title":"Biosorption of Zn(II) by live and dead cells of Streptomyces ciscaucasicus strain CCNWHX 72-14","volume":"179","author":"Li","year":"2010","journal-title":"J. Hazard. Mater."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"133232","DOI":"10.1016\/j.foodchem.2022.133232","article-title":"Enzyme-modulated photothermal immunoassay of chloramphenicol residues in milk and egg using a self-calibrated thermal imager","volume":"392","author":"Wei","year":"2022","journal-title":"Food Chem."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.chroma.2016.12.039","article-title":"Magnetic ionic liquid aqueous two-phase system coupled with high performance liquid chromatography: A rapid approach for determination of chloramphenicol in water environment","volume":"1481","author":"Yao","year":"2017","journal-title":"J. Chromatogr. A"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.cclet.2014.10.026","article-title":"Analysis of chloramphenicol in honey by on-line pretreatment liquid chromatography\u2013tandem mass spectrometry","volume":"26","author":"Kawano","year":"2015","journal-title":"Chin. Chem. Lett."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.bios.2016.09.002","article-title":"Photoresponsive colorimetric immunoassay based on chitosan modified AgI\/TiO2 heterojunction for highly sensitive chloramphenicol detection","volume":"87","author":"Chang","year":"2017","journal-title":"Biosens. Bioelectron."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"122349","DOI":"10.1016\/j.talanta.2021.122349","article-title":"Label free structure-switching fluorescence polarization detection of chloramphenicol with truncated aptamer","volume":"230","author":"Ma","year":"2021","journal-title":"Talanta"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"113870","DOI":"10.1016\/j.jelechem.2020.113870","article-title":"An electrochemiluminescence aptamer sensor for chloramphenicol based on GO-QDs nanocomposites and enzyme-linked aptamers","volume":"860","author":"He","year":"2020","journal-title":"Electroanal. Chem."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"107887","DOI":"10.1016\/j.microc.2022.107887","article-title":"Molecularly imprinted electrochemical sensor based on multi-walled carbon nanotubes for specific recognition and determination of chloramphenicol in milk","volume":"182","author":"Geng","year":"2022","journal-title":"Microchem. J."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.cej.2015.05.045","article-title":"Preparation and characterization of molecular imprinted polymer functionalized with core\/shell magnetic particles (Fe3O4 @SiO2@MIP) for the simultaneous recognition and enrichment of four taxoids in Taxus \u00d7 media","volume":"279","author":"Fan","year":"2015","journal-title":"Chem Eng. J."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"130959","DOI":"10.1016\/j.snb.2021.130959","article-title":"Selection of broad-spectrum aptamer and its application in fabrication of aptasensor for detection of aminoglycoside antibiotics residues in milk","volume":"351","author":"Yue","year":"2022","journal-title":"Sensor Actuat B-Chem."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"106850","DOI":"10.1016\/j.jece.2021.106850","article-title":"SiO2-coated molecularly imprinted sensor based on Si quantum dots for selective detection of catechol in river water","volume":"10","author":"Xu","year":"2022","journal-title":"J. Environ. Chem. Eng."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"102183","DOI":"10.1016\/j.surfin.2022.102183","article-title":"Multifunctional stable PDA\/RGO\/MOFs&SiO2-COOH membrane with excellent flux and anti-fouling performance for the separation of organic dye and oil\/water","volume":"33","author":"Liu","year":"2022","journal-title":"Surf. Interfaces"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"108854","DOI":"10.1016\/j.lwt.2019.108854","article-title":"Removal of patulin in apple juice based on novel magnetic molecularly imprinted adsorbent Fe3O4@SiO2@CS-GO@MIP","volume":"118","author":"Sun","year":"2020","journal-title":"Lwt"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"122496","DOI":"10.1016\/j.talanta.2021.122496","article-title":"Fabrication of metal coordination-synergistic magnetic imprinted microspheres based on ligand-free Fe3O4-Cu for specific recognition of bovine hemoglobin","volume":"233","author":"Hao","year":"2021","journal-title":"Talanta"}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/23\/3\/1346\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T18:15:26Z","timestamp":1760120126000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/23\/3\/1346"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,25]]},"references-count":46,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2023,2]]}},"alternative-id":["s23031346"],"URL":"https:\/\/doi.org\/10.3390\/s23031346","relation":{},"ISSN":["1424-8220"],"issn-type":[{"value":"1424-8220","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,25]]}}}