{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T10:28:24Z","timestamp":1768472904520,"version":"3.49.0"},"reference-count":37,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T00:00:00Z","timestamp":1675036800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62271176"],"award-info":[{"award-number":["62271176"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["JCKY2017412C003"],"award-info":[{"award-number":["JCKY2017412C003"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["JJKH20200167KJ"],"award-info":[{"award-number":["JJKH20200167KJ"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012335","name":"National Defense Basic Scientific Research Program of China","doi-asserted-by":"publisher","award":["62271176"],"award-info":[{"award-number":["62271176"]}],"id":[{"id":"10.13039\/501100012335","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012335","name":"National Defense Basic Scientific Research Program of China","doi-asserted-by":"publisher","award":["JCKY2017412C003"],"award-info":[{"award-number":["JCKY2017412C003"]}],"id":[{"id":"10.13039\/501100012335","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012335","name":"National Defense Basic Scientific Research Program of China","doi-asserted-by":"publisher","award":["JJKH20200167KJ"],"award-info":[{"award-number":["JJKH20200167KJ"]}],"id":[{"id":"10.13039\/501100012335","id-type":"DOI","asserted-by":"publisher"}]},{"name":"\u201c13th five-year plan\u201d Scientific Research Planning Program from the Jilin Provincial Department of Education","award":["62271176"],"award-info":[{"award-number":["62271176"]}]},{"name":"\u201c13th five-year plan\u201d Scientific Research Planning Program from the Jilin Provincial Department of Education","award":["JCKY2017412C003"],"award-info":[{"award-number":["JCKY2017412C003"]}]},{"name":"\u201c13th five-year plan\u201d Scientific Research Planning Program from the Jilin Provincial Department of Education","award":["JJKH20200167KJ"],"award-info":[{"award-number":["JJKH20200167KJ"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Exhaled nitric oxide trace gas at the ppb level is a biomarker of human airway inflammation. To detect this, we developed a method for the collection of active pumping electronic nose bionic chamber gas. An optimization algorithm based on multivariate regression (MR) and genetic algorithm\u2013back propagation (GA-BP) was proposed to improve the accuracy of trace-level gas detection. An electronic nose was used to detect NO gas at the ppb level by substituting breathing gas with a sample gas. The impact of the pump suction flow capacity variation on the response of the electronic nose system was determined using an ANOVA. Further, the optimization algorithm based on MR and GA-BP was studied for flow correction. The results of this study demonstrate an increase in the detection accuracy of the system by more than twofold, from 17.40%FS before correction to 6.86%FS after correction. The findings of this research lay the technical groundwork for the practical application of electronic nose systems in the daily monitoring of FeNO.<\/jats:p>","DOI":"10.3390\/s23031524","type":"journal-article","created":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T08:56:26Z","timestamp":1675068986000},"page":"1524","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Multivariate Regression in Conjunction with GA-BP for Optimization of Data Processing of Trace NO Gas Flow in Active Pumping Electronic Nose"],"prefix":"10.3390","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7879-4435","authenticated-orcid":false,"given":"Pengjiao","family":"Sun","sequence":"first","affiliation":[{"name":"The Higher Educational Key Laboratory for Measuring & Control Technology and Instrumentation of Heilongjiang Province, Harbin University of Science and Technology, Harbin 150080, China"},{"name":"Electronics and Communication Engineering School, Jilin Technology College of Electronic Information, Jilin 132021, China"}]},{"given":"Yunbo","family":"Shi","sequence":"additional","affiliation":[{"name":"The Higher Educational Key Laboratory for Measuring & Control Technology and Instrumentation of Heilongjiang Province, Harbin University of Science and Technology, Harbin 150080, China"},{"name":"Heilongjiang Province Key Laboratory of Laser Spectroscopy Technology and Application, Harbin University of Science and Technology, Harbin 150080, China"},{"name":"National Experimental Teaching Demonstration Center for Measurement and Control Technology and Instrumentation, Harbin University of Science and Technology, Harbin 150080, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0760-833X","authenticated-orcid":false,"given":"Yeping","family":"Shi","sequence":"additional","affiliation":[{"name":"The Higher Educational Key Laboratory for Measuring & Control Technology and Instrumentation of Heilongjiang Province, Harbin University of Science and Technology, Harbin 150080, China"},{"name":"Electronics and Communication Engineering School, Jilin Technology College of Electronic Information, Jilin 132021, China"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.tifs.2020.02.028","article-title":"Principles and recent advances in electronic nose for quality inspection of agricultural and food products","volume":"99","author":"Ali","year":"2020","journal-title":"Trends Food Sci. 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