{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T00:57:59Z","timestamp":1771635479206,"version":"3.50.1"},"reference-count":47,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T00:00:00Z","timestamp":1679875200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation (NSF-PFI) Partnership for Innovation","doi-asserted-by":"publisher","award":["2122901"],"award-info":[{"award-number":["2122901"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation (NSF-PFI) Partnership for Innovation","doi-asserted-by":"publisher","award":["1914240"],"award-info":[{"award-number":["1914240"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation (NSF-PFI) Partnership for Innovation","doi-asserted-by":"publisher","award":["ADHS18-198877"],"award-info":[{"award-number":["ADHS18-198877"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"name":"A.J. and Sigismunda Palumbo Charitable Trust, NSF","award":["2122901"],"award-info":[{"award-number":["2122901"]}]},{"name":"A.J. and Sigismunda Palumbo Charitable Trust, NSF","award":["1914240"],"award-info":[{"award-number":["1914240"]}]},{"name":"A.J. and Sigismunda Palumbo Charitable Trust, NSF","award":["ADHS18-198877"],"award-info":[{"award-number":["ADHS18-198877"]}]},{"DOI":"10.13039\/100008335","name":"Arizona Biomedical Research Commission","doi-asserted-by":"publisher","award":["2122901"],"award-info":[{"award-number":["2122901"]}],"id":[{"id":"10.13039\/100008335","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008335","name":"Arizona Biomedical Research Commission","doi-asserted-by":"publisher","award":["1914240"],"award-info":[{"award-number":["1914240"]}],"id":[{"id":"10.13039\/100008335","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008335","name":"Arizona Biomedical Research Commission","doi-asserted-by":"publisher","award":["ADHS18-198877"],"award-info":[{"award-number":["ADHS18-198877"]}],"id":[{"id":"10.13039\/100008335","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Mayo Clinic\u2014Arizona State University Health Alliance (Team Science Award)","award":["2122901"],"award-info":[{"award-number":["2122901"]}]},{"name":"Mayo Clinic\u2014Arizona State University Health Alliance (Team Science Award)","award":["1914240"],"award-info":[{"award-number":["1914240"]}]},{"name":"Mayo Clinic\u2014Arizona State University Health Alliance (Team Science Award)","award":["ADHS18-198877"],"award-info":[{"award-number":["ADHS18-198877"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Colorimetric sensors are widely used because of their inherent advantages including accuracy, rapid response, ease-of-use, and low costs; however, they usually lack reusability, which precludes the continuous use of a single sensor. We have developed a threshold-responsive colorimetric system that enables repeated analyte measurements by a single colorimetric sensor. The threshold responsive algorithm automatically adjusts the sensor exposure time to the analyte and measurement frequency according to the sensor response. The system registers the colorimetric sensor signal change rate, prevents the colorimetric sensor from reaching saturation, and allows the sensor to fully regenerate before the next measurement is started. The system also addresses issues common to colorimetric sensors, including the response time and range of detection. We demonstrate the benefits and feasibility of this novel system, using colorimetric sensors for ammonia and carbon dioxide gases for continuous monitoring of up to (at least) 60 detection cycles without signs of analytical performance degradation of the sensors.<\/jats:p>","DOI":"10.3390\/s23073496","type":"journal-article","created":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T05:34:30Z","timestamp":1679895270000},"page":"3496","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Threshold-Responsive Colorimetric Sensing System for the Continuous Monitoring of Gases"],"prefix":"10.3390","volume":"23","author":[{"given":"Manni","family":"Mo","sequence":"first","affiliation":[{"name":"Health Futures Center, Arizona State University, Phoenix, AZ 85054, USA"},{"name":"Center for Bioelectronics and Biosensors, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA"},{"name":"Division of Nephrology, Mayo Clinic, Scottsdale, AZ 85259, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5900-4354","authenticated-orcid":false,"given":"Bo","family":"Fu","sequence":"additional","affiliation":[{"name":"Health Futures Center, Arizona State University, Phoenix, AZ 85054, USA"},{"name":"Center for Bioelectronics and Biosensors, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA"},{"name":"Division of Nephrology, Mayo Clinic, Scottsdale, AZ 85259, USA"},{"name":"School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, AZ 85287, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1312-6863","authenticated-orcid":false,"given":"Piyush","family":"Hota","sequence":"additional","affiliation":[{"name":"Health Futures Center, Arizona State University, Phoenix, AZ 85054, USA"},{"name":"Center for Bioelectronics and Biosensors, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA"},{"name":"Division of Nephrology, Mayo Clinic, Scottsdale, AZ 85259, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6875-6603","authenticated-orcid":false,"given":"Pinar","family":"Cay-Durgun","sequence":"additional","affiliation":[{"name":"Center for Bioelectronics and Biosensors, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA"}]},{"given":"Ran","family":"Wang","sequence":"additional","affiliation":[{"name":"Center for Bioelectronics and Biosensors, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA"}]},{"given":"Edward H.","family":"Cheng","sequence":"additional","affiliation":[{"name":"Health Futures Center, Arizona State University, Phoenix, AZ 85054, USA"},{"name":"Center for Bioelectronics and Biosensors, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA"}]},{"given":"Peter","family":"Wiktor","sequence":"additional","affiliation":[{"name":"Center for Bioelectronics and Biosensors, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA"}]},{"given":"Francis","family":"Tsow","sequence":"additional","affiliation":[{"name":"Center for Bioelectronics and Biosensors, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA"}]},{"given":"Leslie","family":"Thomas","sequence":"additional","affiliation":[{"name":"Health Futures Center, Arizona State University, Phoenix, AZ 85054, USA"},{"name":"Division of Nephrology, Mayo Clinic, Scottsdale, AZ 85259, USA"},{"name":"School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, AZ 85287, USA"}]},{"given":"Mary Laura","family":"Lind","sequence":"additional","affiliation":[{"name":"Health Futures Center, Arizona State University, Phoenix, AZ 85054, USA"},{"name":"Center for Bioelectronics and Biosensors, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA"},{"name":"Division of Nephrology, Mayo Clinic, Scottsdale, AZ 85259, USA"},{"name":"School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, AZ 85287, USA"}]},{"given":"Erica","family":"Forzani","sequence":"additional","affiliation":[{"name":"Health Futures Center, Arizona State University, Phoenix, AZ 85054, USA"},{"name":"Center for Bioelectronics and Biosensors, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA"},{"name":"Division of Nephrology, Mayo Clinic, Scottsdale, AZ 85259, USA"},{"name":"School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, AZ 85287, USA"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"5375","DOI":"10.1021\/acs.analchem.8b00506","article-title":"Gradient-Based Colorimetric Sensors for Continuous Gas Monitoring","volume":"90","author":"Lin","year":"2018","journal-title":"Anal. Chem."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1109\/JSEN.2011.2174218","article-title":"A Microfluidic-Colorimetric Sensor for Continuous Monitoring of Reactive Environmental Chemicals","volume":"12","author":"Wang","year":"2012","journal-title":"IEEE Sens. J."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/j.msec.2017.05.018","article-title":"Colorimetric Sensors for Rapid Detection of Various Analytes","volume":"78","author":"Piriya","year":"2017","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1016\/S1872-2040(20)60057-3","article-title":"Progress in Paper-Based Colorimetric Sensor Array","volume":"48","author":"Li","year":"2020","journal-title":"Chin. J. Anal. Chem."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/j.talanta.2019.06.034","article-title":"Ammonia Gas Sensors: A Comprehensive Review","volume":"204","author":"Kwak","year":"2019","journal-title":"Talanta"},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Driau, C., F\u00e0brega, C., Benito-Altamirano, I., Pfeiffer, P., Casals, O., and Prades, J.D. (2019, January 26\u201329). Compact, versatile and cost-effective colorimetric gas sensors. Proceedings of the ISOEN, Fukuoka, Japan.","DOI":"10.1109\/ISOEN.2019.8823240"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1002\/bio.4130","article-title":"Recent Advances of Environmental Pollutants Detection via Paper-Based Sensing Strategy","volume":"36","author":"Zou","year":"2021","journal-title":"Luminescence"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1039\/D0EN00449A","article-title":"Recent Advances in the Design of Colorimetric Sensors for Environmental Monitoring","volume":"7","author":"Liu","year":"2020","journal-title":"Environ. Sci. Nano"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1021\/acssensors.7b00722","article-title":"High Performance Colorimetric Carbon Monoxide Sensor for Continuous Personal Exposure Monitoring","volume":"3","author":"Lin","year":"2018","journal-title":"ACS Sens."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"127572","DOI":"10.1016\/j.snb.2019.127572","article-title":"Highly Sensitive Reflection Based Colorimetric Gas Sensor to Detect CO in Realistic Fire Scenarios","volume":"306","author":"Pannek","year":"2020","journal-title":"Sens. Actuators B Chem."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Weber, C., El-Safoury, M., Pannek, C., Engel, L., Eberhardt, A., Bauersfeld, M.-L., and W\u00f6llenstein, J. (2020, January 22\u201325). Multispectral Readout System for Detecting Tiny Color Changes of Gas Sensitive Colorimetric Dyes. Proceedings of the SMSI 2020-Sensors and Instrumentation, Virtual.","DOI":"10.5162\/SMSI2021\/B10.3"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.foodcont.2015.07.038","article-title":"Development and Validation of a Colorimetric Sensor Array for Fish Spoilage Monitoring","volume":"60","author":"Morsy","year":"2016","journal-title":"Food Control"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.jcis.2020.03.040","article-title":"A Polydiacetylene-Based Colorimetric Sensor as an Active Use-by Date Indicator for Milk","volume":"572","author":"Weston","year":"2020","journal-title":"J. Colloid Interface Sci."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.tifs.2018.09.001","article-title":"Colorimetric Sensor Arrays Based on Chemo-Responsive Dyes for Food Odor Visualization","volume":"81","year":"2018","journal-title":"Trends Food Sci. Technol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1080\/10408347.2016.1233805","article-title":"Colorimetric Sensor Arrays for the Detection and Identification of Chemical Weapons and Explosives","volume":"47","author":"Kangas","year":"2017","journal-title":"Crit. Rev. Anal. Chem."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"130278","DOI":"10.1016\/j.snb.2021.130278","article-title":"Colorimetric and Fluorescent Sensors for Detection of Nerve Agents and Organophosphorus Pesticides","volume":"344","author":"Chen","year":"2021","journal-title":"Sens. Actuators B Chem."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"14","DOI":"10.3390\/appliedchem1010003","article-title":"The Past, Present and Future in Tube- and Paper-Based Colorimetric Gas Detectors","volume":"1","author":"Kawamura","year":"2021","journal-title":"AppliedChem"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.trac.2019.05.034","article-title":"Biosensors for Explosives: State of Art and Future Trends","volume":"118","author":"Liu","year":"2019","journal-title":"TrAC-Trends Anal. Chem."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.trac.2019.06.017","article-title":"Advances in Colorimetric and Optical Sensing for Gaseous Volatile Organic Compounds","volume":"118","author":"Azzouz","year":"2019","journal-title":"TrAC-Trends Anal. Chem."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"7810","DOI":"10.1021\/acs.analchem.5b01499","article-title":"Hand-Held Reader for Colorimetric Sensor Arrays","volume":"87","author":"Askim","year":"2015","journal-title":"Anal. Chem."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1021\/acs.analchem.8b04321","article-title":"Colorimetric Sensor Array for Monitoring CO and Ethylene","volume":"91","author":"Li","year":"2019","journal-title":"Anal. Chem."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"18512","DOI":"10.1109\/JSEN.2021.3089290","article-title":"A Highly Sensitive Colorimetric Gas Sensor Based on Indium Oxide Nanostructures for H2S Detection at Room Temperature","volume":"21","author":"Devi","year":"2021","journal-title":"IEEE Sens. J."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1109\/LED.2021.3064044","article-title":"Two-Dimensional Pixel-Level Photometric and Colorimetric Mass-Distribution Measurement of Micro-Displays","volume":"42","author":"Zheng","year":"2021","journal-title":"IEEE Electron. Device Lett."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"112896","DOI":"10.1016\/j.sna.2021.112896","article-title":"Portable and Autonomous Device for Real-Time Colorimetric Detection: Validation for Phosphorous and Nitrite Detection","volume":"330","author":"Pal","year":"2021","journal-title":"Sens. Actuators A Phys."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Lai, X., Guo, Q., Shi, Z., Chen, H., and Li, D. (2021, January 25\u201329). Rubik\u2019s Cube-Like Multifunctional Sensing Platform. Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), Virtual.","DOI":"10.1109\/MEMS51782.2021.9375368"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"129066","DOI":"10.1016\/j.snb.2020.129066","article-title":"An Ultra-Sensitive Colorimetric Sensor Based on Smartphone for Pyrophosphate Determination","volume":"329","author":"Dong","year":"2021","journal-title":"Sens. Actuators B Chem."},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Fisher, R., Anderson, K., and Christen, J.B. (2021, January 9\u201311). Using Machine Learning to Objectively Determine Colorimetric Assay Results from Cell Phone Photos Taken under Ambient Lighting. Proceedings of the Midwest Symposium on Circuits and Systems, Lansing, MI, USA.","DOI":"10.1109\/MWSCAS47672.2021.9531902"},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Fairclough, S.M., Giannetti, C., Wagner, I., and Shakeel, H. (2020, January 16\u201319). Colorimetric Sensor for PH Monitoring of Liquid Samples Using Bubble Wrap and Mobile Phone Camera. Proceedings of the FLEPS 2020-IEEE International Conference on Flexible and Printable Sensors and Systems, Manchester, UK.","DOI":"10.1109\/FLEPS49123.2020.9239445"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"17665","DOI":"10.1109\/JSEN.2021.3052880","article-title":"Modification of MCM-410-Based Core-Shell for Construction of a Colorimetric Gas Sensor","volume":"21","author":"Esmaeili","year":"2021","journal-title":"IEEE Sens. J."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"214102","DOI":"10.1016\/j.ccr.2021.214102","article-title":"Structural Design of Metal\u2013Organic Frameworks with Tunable Colorimetric Responses for Visual Sensing Applications","volume":"446","author":"Feng","year":"2021","journal-title":"Coord. Chem. Rev."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1038\/35021028","article-title":"A Colorimetric Sensor Array for Odour Visualization","volume":"406","author":"Rakow","year":"2000","journal-title":"Nature"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1021\/acssensors.6b00492","article-title":"Portable Optoelectronic Nose for Monitoring Meat Freshness","volume":"1","author":"Li","year":"2016","journal-title":"ACS Sens."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1021\/acs.analchem.0c02997","article-title":"Membrane-Based Portable Colorimetric Gaseous Chlorine Sensing Probe","volume":"93","author":"Zhou","year":"2021","journal-title":"Anal. Chem."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"3903","DOI":"10.1109\/JSEN.2022.3145046","article-title":"Trimesic Acid-Based Co(II) MOFs as Colorimetric Sensor for Detection of Ammonia Gas","volume":"22","author":"Sotirov","year":"2022","journal-title":"IEEE Sens. J."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1021\/acssensors.0c01971","article-title":"Gradient-Based Colorimetric Array Sensor for Continuous Monitoring of Multiple Gas Analytes","volume":"6","author":"Lin","year":"2021","journal-title":"ACS Sens."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1021\/ac7016162","article-title":"Frequency-Coded Chemical Sensors","volume":"80","author":"Tsow","year":"2008","journal-title":"Anal. Chem."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"6267","DOI":"10.1021\/la503533g","article-title":"Biosensor Regeneration: A Review of Common Techniques and Outcomes","volume":"31","author":"Goode","year":"2015","journal-title":"Langmuir"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/j.snb.2018.02.100","article-title":"A Novel Luminol Derivative and Its Functionalized Filter-Paper for Reversible Double-Wavelength Colorimetric pH Detection in Fruit Juice","volume":"262","author":"Yan","year":"2018","journal-title":"Sens. Actuators B Chem."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"2800610","DOI":"10.1109\/JTEHM.2018.2840678","article-title":"A Handheld, Colorimetric Optoelectronic Dynamics Analyzer for Measuring Total Ammonia of Biological Samples","volume":"6","author":"Liu","year":"2018","journal-title":"IEEE J. Transl. Eng. Health Med."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.snb.2013.12.110","article-title":"A Novel Real-Time Carbon Dioxide Analyzer for Health and Environmental Applications","volume":"195","author":"Zhao","year":"2014","journal-title":"Sens. Actuators B Chem."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0003-2670(95)00540-4","article-title":"Study of the performance of an optochemical sensor for ammonia","volume":"320","author":"Trinkel","year":"1996","journal-title":"Anal. Chim. Acta"},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"McGrath, M.J., and Scanaill, C.N. (2013). Sensor Technologies: Healthcare, Wellness, and Environmental Applications, Springer Nature.","DOI":"10.1007\/978-1-4302-6014-1"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"184702","DOI":"10.1063\/1.5095867","article-title":"Rates of Adsorption and Desorption: Entropic Contributions and Errors Due to Mean-Field Approximations","volume":"150","author":"Agarwal","year":"2019","journal-title":"J. Chem. Phys."},{"key":"ref_44","unstructured":"James, A., and Goodrich, J.F.K. (2007). Binding and Kinetics for Molecular Biologists, Cold Spring Harbor Laboratory Press."},{"key":"ref_45","unstructured":"Schuck, P., and Zhao, H. (2010). Methods in Molecular Biology, Humana."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"100403","DOI":"10.1016\/j.sbsr.2021.100403","article-title":"Wearable Electrochemical Flexible Biosensors: With the Focus on Affinity Biosensors","volume":"32","author":"Takaloo","year":"2021","journal-title":"Sens. Bio-Sens. Res."},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Mujahid, A., Afzal, A., and Dickert, F.L. (2019). An Overview of High Frequency Acoustic Sensors\u2014QCMs, SAWs and FBARs\u2014Chemical and Biochemical Applications. Sensors, 19.","DOI":"10.3390\/s19204395"}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/23\/7\/3496\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:03:56Z","timestamp":1760123036000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/23\/7\/3496"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,27]]},"references-count":47,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2023,4]]}},"alternative-id":["s23073496"],"URL":"https:\/\/doi.org\/10.3390\/s23073496","relation":{},"ISSN":["1424-8220"],"issn-type":[{"value":"1424-8220","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,27]]}}}