{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:10:13Z","timestamp":1760148613926,"version":"build-2065373602"},"reference-count":63,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2023,5,22]],"date-time":"2023-05-22T00:00:00Z","timestamp":1684713600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>This study aimed to investigate whether sample entropy (SEn) and peak frequency values observed in treadmill walking could provide physical therapists valuable insights into gait rehabilitation following total knee arthroplasty (TKA). It was recognized that identifying movement strategies that during rehabilitation are initially adaptive but later start to hamper full recovery is critical to meet the clinical goals and minimize the risk of contralateral TKA. Eleven TKA patients were asked to perform clinical walking tests and a treadmill walking task at four different points in time (pre-TKA, 3, 6, and 12 months post-TKA). Eleven healthy peers served as the reference group. The movements of the legs were digitized with inertial sensors and SEn and peak frequency of the recorded rotational velocity\u2013time functions were analyzed in the sagittal plane. SEn displayed a systematic increase during recovery in TKA patients (p &lt; 0.001). Furthermore, lower peak frequency (p = 0.01) and sample entropy (p = 0.028) were found during recovery for the TKA leg. Movement strategies that initially are adaptive, and later hamper recovery, tend to diminish after 12 months post-TKA. It is concluded that inertial-sensor-based SEn and peak frequency analyses of treadmill walking enrich the assessment of movement rehabilitation after TKA.<\/jats:p>","DOI":"10.3390\/s23104968","type":"journal-article","created":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T02:02:27Z","timestamp":1684807347000},"page":"4968","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Inertial-Sensor-Based Monitoring of Sample Entropy and Peak Frequency Changes in Treadmill Walking during Recovery after Total Knee Arthroplasty"],"prefix":"10.3390","volume":"23","author":[{"given":"Werner A. F.","family":"van de Ven","sequence":"first","affiliation":[{"name":"Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, 6525 GD Nijmegen, The Netherlands"},{"name":"FysioHolland Twente, 7512 AC Enschede, The Netherlands"}]},{"given":"Jurjen","family":"Bosga","sequence":"additional","affiliation":[{"name":"Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, 6525 GD Nijmegen, The Netherlands"}]},{"given":"Wim","family":"Hullegie","sequence":"additional","affiliation":[{"name":"Physiotherapy Practice Hullegie and Richter MSC, 7512 AC Enschede, The Netherlands"}]},{"given":"Wiebe C.","family":"Verra","sequence":"additional","affiliation":[{"name":"Medisch Spectrum Twente, Department of Orthopedic Surgery, 7512 KZ Enschede, The Netherlands"}]},{"given":"Ruud G. J.","family":"Meulenbroek","sequence":"additional","affiliation":[{"name":"Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, 6525 GD Nijmegen, The Netherlands"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1002\/jor.24175","article-title":"Stiff Knee Gait May Increase Risk of Second Total Knee Arthroplasty","volume":"37","author":"Zeni","year":"2019","journal-title":"J. Orthop. Res."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.clinbiomech.2011.11.006","article-title":"Determinants of Co-Contraction during Walking before and after Arthroplasty for Knee Osteoarthritis","volume":"27","author":"Meijer","year":"2012","journal-title":"Clin. 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