{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T23:35:37Z","timestamp":1783294537339,"version":"3.54.6"},"reference-count":35,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2023,5,24]],"date-time":"2023-05-24T00:00:00Z","timestamp":1684886400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science (JSPS) KAKENHI","doi-asserted-by":"publisher","award":["JP19KK0259"],"award-info":[{"award-number":["JP19KK0259"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Cooperative Research Project of the Research Center for Biomedical Engineering","award":["JP19KK0259"],"award-info":[{"award-number":["JP19KK0259"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>In orthodontics, understanding the pressure of oral soft tissues on teeth is important to elucidate the cause and establish treatment methods. We developed a small wireless mouthguard (MG)-type device that continuously and unrestrainedly measures pressure, which had previously been unachieved, and evaluated its feasibility in human subjects. First, the optimal device components were considered. Next, the devices were compared with wired-type systems. Subsequently, the devices were fabricated for human testing to measure tongue pressure during swallowing. The highest sensitivity (51\u2013510 g\/cm2) with minimum error (CV &lt; 5%) was obtained using an MG device with polyethylene terephthalate glycol and ethylene vinyl acetate for the lower and upper layers, respectively, and with a 4 mm PMMA plate. A high correlation coefficient (0.969) was observed between the wired and wireless devices. In the measurements of tongue pressure on teeth during swallowing, 132.14 \u00b1 21.37 g\/cm2 for normal and 201.17 \u00b1 38.12 g\/cm2 for simulated tongue thrust were found to be significantly different using a t-test (n = 50, p = 6.2 \u00d7 10\u221219), which is consistent with the results of a previous study. This device can contribute to assessing tongue thrusting habits. In the future, this device is expected to measure changes in the pressure exerted on teeth during daily life.<\/jats:p>","DOI":"10.3390\/s23115027","type":"journal-article","created":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T02:30:06Z","timestamp":1684981806000},"page":"5027","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Real-Time Continuous Monitoring of Oral Soft Tissue Pressure with a Wireless Mouthguard Device for Assessing Tongue Thrusting Habits"],"prefix":"10.3390","volume":"23","author":[{"given":"Hidekazu","family":"Matsumoto","sequence":"first","affiliation":[{"name":"Department of Maxillofacial Orthognathics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8549, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keisuke","family":"Tomoto","sequence":"additional","affiliation":[{"name":"Department of Biomedical Devices and Instrumentation, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo 101-0062, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gentaro","family":"Kawase","sequence":"additional","affiliation":[{"name":"Department of Biomedical Devices and Instrumentation, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo 101-0062, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5608-8863","authenticated-orcid":false,"given":"Kenta","family":"Iitani","sequence":"additional","affiliation":[{"name":"Department of Biomedical Devices and Instrumentation, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo 101-0062, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1683-1496","authenticated-orcid":false,"given":"Koji","family":"Toma","sequence":"additional","affiliation":[{"name":"Department of Biomedical Devices and Instrumentation, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo 101-0062, Japan"},{"name":"Department of Electronic Engineering, Shibaura Institute of Technology, College of Engineering, Tokyo 135-8548, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1555-1281","authenticated-orcid":false,"given":"Takahiro","family":"Arakawa","sequence":"additional","affiliation":[{"name":"Department of Biomedical Devices and Instrumentation, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo 101-0062, Japan"},{"name":"Department of Electric and Electronic Engineering, Tokyo University of Technology, Tokyo 192-0982, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0709-4957","authenticated-orcid":false,"given":"Kohji","family":"Mitsubayashi","sequence":"additional","affiliation":[{"name":"Department of Biomedical Devices and Instrumentation, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo 101-0062, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0580-4510","authenticated-orcid":false,"given":"Keiji","family":"Moriyama","sequence":"additional","affiliation":[{"name":"Department of Maxillofacial Orthognathics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8549, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1109\/JBHI.2015.2450362","article-title":"Big Data for Health","volume":"19","author":"Poon","year":"2015","journal-title":"IEEE J. Biomed. Health Inform."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Li, X., Dunn, J., Salins, D., Zhou, G., Zhou, W., Sch\u00fcssler-Fiorenza Rose, S.M., Perelman, D., Colbert, E., Runge, R., and Rego, S. (2017). Digital Health: Tracking Physiomes and Activity Using Wearable Biosensors Reveals Useful Health-Related Information. PLoS Biol., 15.","DOI":"10.1371\/journal.pbio.2001402"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1109\/TBME.2014.2309951","article-title":"Unobtrusive Sensing and Wearable Devices for Health Informatics","volume":"61","author":"Zheng","year":"2014","journal-title":"IEEE Trans. Biomed. Eng."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1038\/s41928-018-0043-y","article-title":"Wearable Sweat Sensors","volume":"1","author":"Bariya","year":"2018","journal-title":"Nat. Electron."},{"key":"ref_5","first-page":"8186","article-title":"Wearable Medical Monitoring Systems Based on Wireless Networks: A Review","volume":"16","author":"Liang","year":"2016","journal-title":"IEEE Sens. J."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"12201","DOI":"10.1021\/acs.analchem.0c01201","article-title":"A Wearable Cellulose Acetate-Coated Mouthguard Biosensor for in Vivo Salivary Glucose Measurement","volume":"92","author":"Arakawa","year":"2020","journal-title":"Anal. Chem."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"14997","DOI":"10.1038\/ncomms14997","article-title":"Wearable Smart Sensor Systems Integrated on Soft Contact Lenses for Wireless Ocular Diagnostics","volume":"8","author":"Kim","year":"2017","journal-title":"Nat. Commun."},{"key":"ref_8","first-page":"1","article-title":"On an Equilibrium Theory of Tooth Position","volume":"33","author":"Weinstein","year":"1963","journal-title":"Angle Orthod."},{"key":"ref_9","first-page":"175","article-title":"Equilibrium Theory Revisited: Factors Influencing Position of the Teeth","volume":"48","author":"Proffit","year":"1978","journal-title":"Angle Orthod."},{"key":"ref_10","first-page":"1","article-title":"Muscle Pressures and Tooth Position: North American Whites and Australian Aborigines","volume":"45","author":"Proffit","year":"1975","journal-title":"Angle Orthod."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1177\/00220345750540061101","article-title":"Lip and Tongue Pressures Related to Dental Arch and Oral Cavity Size in Australian Aborigines","volume":"54","author":"Proffit","year":"1975","journal-title":"J. Dent. Res."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1016\/0002-9416(69)90040-2","article-title":"A Critical Appraisal of Tongue-Thrusting","volume":"55","author":"Tulley","year":"1969","journal-title":"Am. J. Orthod."},{"key":"ref_13","first-page":"73","article-title":"Effect of Tongue Thrust Swallowing on Position of Anterior Teeth","volume":"3","author":"Jalaly","year":"2009","journal-title":"J. Dent. Res. Dent. Clin. Dent. Prospect."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"2","DOI":"10.4103\/0976-237X.111585","article-title":"Comparison of Soft-Tissue, Dental, and Skeletal Characteristics in Children with and without Tongue Thrusting Habit","volume":"4","author":"Dixit","year":"2013","journal-title":"Contemp. Clin. Dent."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/S0889-5406(98)70307-5","article-title":"The Nature of Arch Width Difference and Palatal Depth of the Anterior Open Bite","volume":"113","author":"Hsu","year":"1998","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_16","first-page":"1","article-title":"Tongue Thrusting Habit: A Review","volume":"2015","author":"Tarvade","year":"2015","journal-title":"Int. J. Contemp. Dent. Med. Rev."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.ajodo.2010.02.030","article-title":"Lip Pressure at Rest and during Function in 2 Groups of Patients with Different Occlusions","volume":"139","author":"Lombardo","year":"2011","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1177\/154405910208100507","article-title":"The Importance of the Level of the Lip Line and Resting Lip Pressure in Class II, Division 2 Malocclusion","volume":"81","author":"Lapatki","year":"2002","journal-title":"J. Dent. Res."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1093\/ejo\/cjq060","article-title":"Association between Intraoral Pressure and Molar Position and Inclination in Subjects with Facial Asymmetry","volume":"33","author":"Takada","year":"2011","journal-title":"Eur. J. Orthod."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1631\/jzus.2007.B0296","article-title":"Pressure from the Lips and the Tongue in Children with Class III Malocclusion","volume":"8","author":"Ruan","year":"2007","journal-title":"J. Zhejiang Univ. Sci. B"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1093\/ejo\/21.3.299","article-title":"Cheek and Tongue Pressures in the Molar Areas and the Atmospheric Pressure in the Palatal Vault in Young Adults","volume":"21","author":"Sieber","year":"1999","journal-title":"Eur. J. Orthod."},{"key":"ref_22","first-page":"662","article-title":"Changes in Lip, Cheek, and Tounge Pressures after Rapid: Maxillary Expansion Using a Diaphragm Pressure Transducer","volume":"73","year":"2003","journal-title":"Angle Orthod."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1177\/00220345630420031801","article-title":"Tongue and Lip Forces Exerted during Deglutition in Subjects with and without an Anterior Open Bite","volume":"42","author":"Kydd","year":"1963","journal-title":"J. Dent. Res."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1093\/ejo\/cjp137","article-title":"Lip and Tongue Pressure in Orthodontic Patients","volume":"32","author":"Lambrechts","year":"2010","journal-title":"Eur. J. Orthod."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"175","DOI":"10.5357\/koubyou.54.175","article-title":"Intraoral Pressure Measurement with Telemetry System","volume":"54","author":"Kato","year":"1987","journal-title":"Kokubyo Gakkai Zasshi."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0889-5406(99)70324-0","article-title":"Effect of Changes in the Breathing Mode and Body Position on Tongue Pressure with Respiratory-Related Oscillations","volume":"115","author":"Takahashi","year":"1999","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/0889-5406(87)90168-5","article-title":"Changes in Lip Pressure Following Extension and Flexion of the Head and at Changed Mode of Breathing","volume":"91","author":"Hellsing","year":"1987","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1111\/j.1365-2842.2006.01708.x","article-title":"A Simple Method for Evaluation of Tongue Position","volume":"34","author":"Tsuiki","year":"2007","journal-title":"J. Oral Rehabil."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1111\/joor.12281","article-title":"Tongue Resting Pressure of the Tongue Anchorage Pad in Different Body Positions: A Pilot Study","volume":"42","author":"Zeng","year":"2015","journal-title":"J. Oral Rehabil."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1093\/ortho\/29.4.307","article-title":"Breathing Modes, Body Positions and Suprahyoid Muscle Activity","volume":"29","author":"Takahashi","year":"2002","journal-title":"J. Orthod."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1136\/thx.37.11.840","article-title":"Respiration during Sleep","volume":"37","author":"Douglas","year":"1982","journal-title":"Thorax"},{"key":"ref_32","first-page":"7","article-title":"Buccal and Lingual Soft Tissue Pressures In Different Malocclusions","volume":"8","author":"Qazi","year":"2016","journal-title":"POJ"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"533","DOI":"10.2319\/070209-370.1","article-title":"Tongue Pressure Changes before, during and after Crib Appliance Therapy","volume":"80","author":"Taslana","year":"2010","journal-title":"Angle Orthod."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.jpor.2008.08.008","article-title":"Newly Developed Sensor Sheet for Measuring Tongue Pressure during Swallowing","volume":"53","author":"Hori","year":"2009","journal-title":"J. Prosthodont. Res."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/S0889-5406(99)70211-8","article-title":"Relationship between the Lingual-Palatal Contact Duration Associated with Swallowing and Maxillofacial Morphology with the Use of Electropalatography","volume":"116","author":"Ichida","year":"1999","journal-title":"Am. J. Orthod. Dentofacial Orthop."}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/23\/11\/5027\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:40:59Z","timestamp":1760125259000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/23\/11\/5027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,24]]},"references-count":35,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2023,6]]}},"alternative-id":["s23115027"],"URL":"https:\/\/doi.org\/10.3390\/s23115027","relation":{},"ISSN":["1424-8220"],"issn-type":[{"value":"1424-8220","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,24]]}}}