{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T03:09:03Z","timestamp":1783825743940,"version":"3.55.0"},"reference-count":98,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T00:00:00Z","timestamp":1685404800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22172104"],"award-info":[{"award-number":["22172104"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["KZ202110028042"],"award-info":[{"award-number":["KZ202110028042"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Beijing Municipal Education Commission","award":["22172104"],"award-info":[{"award-number":["22172104"]}]},{"name":"Beijing Municipal Education Commission","award":["KZ202110028042"],"award-info":[{"award-number":["KZ202110028042"]}]},{"name":"Beijing Natural Science Foundation","award":["22172104"],"award-info":[{"award-number":["22172104"]}]},{"name":"Beijing Natural Science Foundation","award":["KZ202110028042"],"award-info":[{"award-number":["KZ202110028042"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>The early detection and prognosis of cancers require sensitive and accurate detection methods; with developments in medicine, electrochemical biosensors have been developed that can meet these clinical needs. However, the composition of biological samples represented by serum is complex; when substances undergo non-specific adsorption to an electrode and cause fouling, the sensitivity and accuracy of the electrochemical sensor are affected. In order to reduce the effects of fouling on electrochemical sensors, a variety of anti-fouling materials and methods have been developed, and enormous progress has been made over the past few decades. Herein, the recent advances in anti-fouling materials and strategies for using electrochemical sensors for tumor markers are reviewed; we focus on new anti-fouling methods that separate the immunorecognition and signal readout platforms.<\/jats:p>","DOI":"10.3390\/s23115202","type":"journal-article","created":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T02:57:10Z","timestamp":1685501830000},"page":"5202","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Anti-Fouling Strategies of Electrochemical Sensors for Tumor Markers"],"prefix":"10.3390","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-5653-285X","authenticated-orcid":false,"given":"Ge","family":"Song","sequence":"first","affiliation":[{"name":"Department of Chemistry, Capital Normal University, Beijing 100048, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongliang","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Capital Normal University, Beijing 100048, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhanfang","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Capital Normal University, Beijing 100048, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Campuzano, S., Seraf\u00edn, V., Gamella, M., Pedrero, M., Y\u00e1\u00f1ez-Sede\u00f1o, P., and Pingarr\u00f3n, J.M. 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