{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T22:13:04Z","timestamp":1780092784142,"version":"3.54.0"},"reference-count":34,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2023,6,20]],"date-time":"2023-06-20T00:00:00Z","timestamp":1687219200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"NIH","award":["R42HL131081"],"award-info":[{"award-number":["R42HL131081"]}]},{"name":"NIH","award":["R41NR019735"],"award-info":[{"award-number":["R41NR019735"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>(1) Background: Mastery of auscultation can be challenging for many healthcare providers. Artificial intelligence (AI)-powered digital support is emerging as an aid to assist with the interpretation of auscultated sounds. A few AI-augmented digital stethoscopes exist but none are dedicated to pediatrics. Our goal was to develop a digital auscultation platform for pediatric medicine. (2) Methods: We developed StethAid\u2014a digital platform for artificial intelligence-assisted auscultation and telehealth in pediatrics\u2014that consists of a wireless digital stethoscope, mobile applications, customized patient-provider portals, and deep learning algorithms. To validate the StethAid platform, we characterized our stethoscope and used the platform in two clinical applications: (1) Still\u2019s murmur identification and (2) wheeze detection. The platform has been deployed in four children\u2019s medical centers to build the first and largest pediatric cardiopulmonary datasets, to our knowledge. We have trained and tested deep-learning models using these datasets. (3) Results: The frequency response of the StethAid stethoscope was comparable to those of the commercially available Eko Core, Thinklabs One, and Littman 3200 stethoscopes. The labels provided by our expert physician offline were in concordance with the labels of providers at the bedside using their acoustic stethoscopes for 79.3% of lungs cases and 98.3% of heart cases. Our deep learning algorithms achieved high sensitivity and specificity for both Still\u2019s murmur identification (sensitivity of 91.9% and specificity of 92.6%) and wheeze detection (sensitivity of 83.7% and specificity of 84.4%). (4) Conclusions: Our team has created a technically and clinically validated pediatric digital AI-enabled auscultation platform. Use of our platform could improve efficacy and efficiency of clinical care for pediatric patients, reduce parental anxiety, and result in cost savings.<\/jats:p>","DOI":"10.3390\/s23125750","type":"journal-article","created":{"date-parts":[[2023,6,21]],"date-time":"2023-06-21T02:30:51Z","timestamp":1687314651000},"page":"5750","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["StethAid: A Digital Auscultation Platform for Pediatrics"],"prefix":"10.3390","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8207-0170","authenticated-orcid":false,"given":"Youness","family":"Arjoune","sequence":"first","affiliation":[{"name":"Sheikh Zayed Institute for Pediatric Surgical Innovation, Children\u2019s National Hospital, Washington, DC 20010, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trong N.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"AusculTech Dx, 2601 University Blvd West #301, Silver Spring, MD 20902, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5842-6221","authenticated-orcid":false,"given":"Tyler","family":"Salvador","sequence":"additional","affiliation":[{"name":"Sheikh Zayed Institute for Pediatric Surgical Innovation, Children\u2019s National Hospital, Washington, DC 20010, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anha","family":"Telluri","sequence":"additional","affiliation":[{"name":"School of Medicine and Health Sciences, George Washington University, Washington, DC 20052, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan C.","family":"Schroeder","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Sleep Medicine, Children\u2019s National Hospital, Washington, DC 20010, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert L.","family":"Geggel","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Boston Children\u2019s Hospital, Boston, MA 02115, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph W.","family":"May","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Walter Reed National Military Medical Center, Bethesda, MD 20814, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dinesh K.","family":"Pillai","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Sleep Medicine, Children\u2019s National Hospital, Washington, DC 20010, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen J.","family":"Teach","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Children\u2019s National Hospital, Washington, DC 20010, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9287-1430","authenticated-orcid":false,"given":"Shilpa J.","family":"Patel","sequence":"additional","affiliation":[{"name":"Division of Emergency Medicine, Children\u2019s National Hospital, Washington, DC 20010, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin W.","family":"Doroshow","sequence":"additional","affiliation":[{"name":"AusculTech Dx, 2601 University Blvd West #301, Silver Spring, MD 20902, USA"},{"name":"Department of Cardiology, Children\u2019s National Hospital, Washington, DC 20010, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raj","family":"Shekhar","sequence":"additional","affiliation":[{"name":"Sheikh Zayed Institute for Pediatric Surgical Innovation, Children\u2019s National Hospital, Washington, DC 20010, USA"},{"name":"AusculTech Dx, 2601 University Blvd West #301, Silver Spring, MD 20902, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,6,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"230","DOI":"10.3121\/cmr.4.3.230","article-title":"Rene Theophile Hyacinthe La\u00ebnnec (1781\u20131826): The man behind the stethoscope","volume":"4","author":"Roguin","year":"2006","journal-title":"Clin. 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