{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T16:12:12Z","timestamp":1777565532040,"version":"3.51.4"},"reference-count":33,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2023,8,11]],"date-time":"2023-08-11T00:00:00Z","timestamp":1691712000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National College Student Innovation Training Program","award":["202210293014Z"],"award-info":[{"award-number":["202210293014Z"]}]},{"name":"College Student Innovation Training Program of Nanjing University of Posts and Telecommunications","award":["none"],"award-info":[{"award-number":["none"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>In this paper, a liquid crystal-modulated metastructure sensor (MS) is proposed that can detect the refractive index (RI) of a liquid and change the detection range under different applied voltages. The regulation of the detection range is based on the different bias states of the liquid crystal at different voltages. By changing the sample in the cavity that is to be detected, the overall electromagnetic characteristics of the device in the resonant state are modified, thus changing the position of the absorption peaks so that different RI correspond to different absorption peaks, and finally realizing the sensing detection. The refractive index unit is denoted as RIU. The range of the refractive index detection is 1.414\u20132.828 and 2.121\u20133.464, and the corresponding absorption peak variation range is 0.8485\u20131.028 THz and 0.7295\u20130.8328 THz, with a sensitivity of 123.8 GHz\/RIU and 75.6 GHz\/RIU, respectively. In addition, an approach to optimizing resonant absorption peaks is explored, which can suppress unwanted absorption generated during the design process by analyzing the energy distribution and directing the current flow on the substrate. Four variables that have a more obvious impact on performance are listed, and the selection and change trend of the numerical values are focused on, fully considering the errors that may be caused by manufacturing and actual use. At the same time, the incident angle and polarization angle are also included in the considered range, and the device shows good stability at these angles. Finally, the influence of the number of resonant rings on the sensing performance is also discussed, and its conclusion has guiding value for optimizing the sensing demand. This new liquid crystal-modulated MS has the advantages of a small size and high sensitivity and is expected to be used for bio-detection, sensing, and so on. All results in this work were obtained with the aid of simulations based on the finite element method.<\/jats:p>","DOI":"10.3390\/s23167122","type":"journal-article","created":{"date-parts":[[2023,8,11]],"date-time":"2023-08-11T12:10:23Z","timestamp":1691755823000},"page":"7122","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["A Liquid Crystal-Modulated Metastructure Sensor for Biosensing"],"prefix":"10.3390","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1431-1294","authenticated-orcid":false,"given":"Siyuan","family":"Liao","sequence":"first","affiliation":[{"name":"College of Electronic and Optical Engineering & College of Flexible Electronics (Future Technology), Nanjing University of Posts and Telecommunications, Nanjing 210023, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Chen","sequence":"additional","affiliation":[{"name":"College of Electronic and Optical Engineering & College of Flexible Electronics (Future Technology), Nanjing University of Posts and Telecommunications, Nanjing 210023, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haocheng","family":"Ma","sequence":"additional","affiliation":[{"name":"College of Electronic and Optical Engineering & College of Flexible Electronics (Future Technology), Nanjing University of Posts and Telecommunications, Nanjing 210023, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingwei","family":"Huang","sequence":"additional","affiliation":[{"name":"College of Electronic and Optical Engineering & College of Flexible Electronics (Future Technology), Nanjing University of Posts and Telecommunications, Nanjing 210023, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junyang","family":"Sui","sequence":"additional","affiliation":[{"name":"College of Electronic and Optical Engineering & College of Flexible Electronics (Future Technology), Nanjing University of Posts and Telecommunications, Nanjing 210023, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9890-8345","authenticated-orcid":false,"given":"Haifeng","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Electronic and Optical Engineering & College of Flexible Electronics (Future Technology), Nanjing University of Posts and Telecommunications, Nanjing 210023, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,8,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Pligovka, A., Lazavenka, A., Turavets, U., Hoha, A., and Salerno, M. (2023). Two-Level 3D Column-like Nanofilms with Hexagonally\u2013Packed Tantalum Fabricated via Anodizing of Al\/Nb and Al\/Ta Layers\u2014A Potential Nano-Optical Biosensor. Materials, 16.","DOI":"10.3390\/ma16030993"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"127705","DOI":"10.1016\/j.physleta.2021.127705","article-title":"Tunable terahertz metamaterial filter based on applying distributed load","volume":"421","author":"Ruan","year":"2021","journal-title":"Phys. Lett. A"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"A57","DOI":"10.1364\/PRJ.446932","article-title":"Polarization-independent multimode interference coupler with anisotropy-engineered bricked metamaterial","volume":"10","author":"Halir","year":"2022","journal-title":"Photonics Res."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"106374","DOI":"10.1016\/j.rinp.2023.106374","article-title":"Multi-peak narrow-band metamaterial absorber for visible to near-infrared wavelengths","volume":"47","author":"Liu","year":"2023","journal-title":"Results Phys."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"63658","DOI":"10.1109\/ACCESS.2022.3183272","article-title":"Graphene-Based Multiband Chiral Metamaterial Absorbers Comprised of Square Split-Ring Resonator Arrays with Different Numbers of Gaps, and Their Equivalent Circuit Model","volume":"10","author":"Asgari","year":"2022","journal-title":"IEEE Access"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"128854","DOI":"10.1016\/j.optcom.2022.128854","article-title":"Mid-infrared chiral metasurface absorbers with split-ellipse structures","volume":"525","author":"Zeng","year":"2022","journal-title":"Opt. Commun."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"108742","DOI":"10.1016\/j.optlastec.2022.108742","article-title":"Experimental characterization of an ultra-broadband dual-mode symmetric Y\u2013junction based on metamaterial waveguides","volume":"157","author":"Cabo","year":"2023","journal-title":"Opt. Laser Technol."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Chen, H., Zhang, Z., Zhang, X., Han, Y., Zhou, Z., and Yang, J. (2022). Multifunctional Plasmon-Induced Transparency Devices Based on Hybrid Metamaterial-Waveguide Systems. Nanomaterials, 12.","DOI":"10.3390\/nano12193273"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"3668","DOI":"10.1109\/ACCESS.2021.3140156","article-title":"A comprehensive survey on antennas on-chip based on metamaterial; metasurface; and substrate integrated waveguide principles for millimeter-waves and terahertz integrated circuits and systems","volume":"10","author":"Alibakhshikenari","year":"2022","journal-title":"IEEE Access"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Pligovka, A., Poznyak, A., and Norek, M. (2021). Optical Properties of Porous Alumina Assisted Niobia Nanostructured Films\u2013Designing 2-D Photonic Crystals Based on Hexagonally Arranged Nanocolumns. Micromachines, 12.","DOI":"10.3390\/mi12060589"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1049\/mia2.12255","article-title":"Size reduction of a conical horn antenna loaded by multi-layer metamaterial lens","volume":"16","author":"Sedaghat","year":"2022","journal-title":"IET Microw. Antennas Propag."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1364\/PRJ.439481","article-title":"Terahertz metalens of hyper-dispersion","volume":"10","author":"Zhao","year":"2022","journal-title":"Photon. Res."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1891","DOI":"10.1364\/OL.452347","article-title":"Terahertz liquid crystal programmable metasurface based on resonance switching","volume":"47","author":"Liu","year":"2022","journal-title":"Opt. Lett."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Yu, H., Wang, H., Wang, Q., Ge, S., and Hu, W. (2023). Liquid Crystal-Tuned Planar Optics in Terahertz Range. Appl. Sci., 13.","DOI":"10.3390\/app13031428"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"109127","DOI":"10.1016\/j.optlastec.2023.109127","article-title":"A polyimide-free configuration for tunable terahertz liquid-crystal-based metasurface with fast response time","volume":"161","author":"Deng","year":"2023","journal-title":"Opt. Laser Technol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"27676","DOI":"10.1364\/OE.399581","article-title":"Continuously tunable intensity modulators with large switching contrasts using liquid crystal elastomer films that are deposited with terahertz metamaterials","volume":"28","author":"Chiang","year":"2020","journal-title":"Opt. Express"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1109\/TAP.2022.3220945","article-title":"A Liquid Crystal Tunable Metamaterial Unit Cell for Dynamic Metasurface Antennas","volume":"71","author":"Wang","year":"2022","journal-title":"IEEE Antennas Propag. Mag."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"108872","DOI":"10.1016\/j.diamond.2022.108872","article-title":"High absorption and a tunable broadband absorption based on the fractal Technology of Infrared Metamaterial Broadband Absorber","volume":"123","author":"Xie","year":"2022","journal-title":"Diam. Relat. Mater."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"e23222","DOI":"10.1002\/mmce.23222","article-title":"Design of an ultra-broadband microwave metamaterial absorber based on multilayer structures","volume":"32","author":"Yao","year":"2022","journal-title":"Int. J. RF Microw. Comput. Aided Eng."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"015507","DOI":"10.1088\/1402-4896\/aca5c9","article-title":"A transparent water-based metamaterial broadband absorber with a tunable absorption band","volume":"98","author":"Yao","year":"2023","journal-title":"Phys. Scr."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1038\/s41598-020-58456-y","article-title":"Ultra-narrowband dielectric metamaterial absorber with ultra-sparse nanowire grids for sensing applications","volume":"10","author":"Liao","year":"2020","journal-title":"Sci. Rep."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"340","DOI":"10.3390\/mi14020340","article-title":"Visible-range multiple-channel metal-shell rod-shaped narrowband plasmonic metamaterial absorber for refractive index and temperature sensing","volume":"14","author":"Chao","year":"2023","journal-title":"Micromachines"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"2863","DOI":"10.1364\/JOSAB.470475","article-title":"Narrowband metamaterial absorbers based on interlaced T-shaped all-dielectric resonators for sensing application","volume":"39","author":"Fan","year":"2022","journal-title":"J. Opt. Soc. Am. B"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"129430","DOI":"10.1016\/j.optcom.2023.129430","article-title":"Flexible terahertz Metamaterial sensor for sensitive detection of imidacloprid","volume":"537","author":"Lang","year":"2023","journal-title":"Opt. Commun."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"14662","DOI":"10.1109\/JSEN.2023.3266496","article-title":"A Tunable Strong Electric Field Ultra-Narrow-Band Fano Resonance Hybrid Metamaterial Sensor Based on LSPR","volume":"23","author":"Wang","year":"2023","journal-title":"IEEE Sens. J."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"7373","DOI":"10.1038\/s41598-023-34514-z","article-title":"Double-negative metamaterial square enclosed QSSR for microwave sensing application in S-band with high sensitivity and Q-factor","volume":"13","author":"Khalil","year":"2023","journal-title":"Sci. Rep."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1007\/s42114-023-00666-9","article-title":"Terahertz metamaterial biosensor based on open square ring","volume":"6","author":"Guo","year":"2023","journal-title":"Adv. Compos. Hybrid Mater."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"105781","DOI":"10.1016\/j.isci.2022.105781","article-title":"Ultra-sensitive terahertz metamaterials biosensor based on luxuriant gaps structure","volume":"26","author":"Chen","year":"2023","journal-title":"Iscience"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1007\/s11082-023-04906-6","article-title":"Design and optimization of highly sensitive multi-band terahertz metamaterial biosensor for coronaviruses detection","volume":"55","author":"Ismail","year":"2023","journal-title":"Opt. Quant. Electron."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1109\/LPT.2022.3202991","article-title":"Terahertz Metamaterials Broadband Perfect Absorber Based on Molybdenum Disulfide","volume":"34","author":"Luo","year":"2022","journal-title":"IEEE Photon. Technol. Lett."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1007\/s11468-019-00930-z","article-title":"A three-dimensional Linear-to-Circular polarization converter tailored by the gravity field","volume":"14","author":"Zeng","year":"2019","journal-title":"Plasmonics"},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Chiang, W.F., Lu, Y.Y., Chen, Y.P., Lin, X.Y., Lim, T.S., Liu, J.H., Le, C.R., and Huang, C.Y. (2021). Passively tunable terahertz filters using liquid crystal cells coated with metamaterials. Coatings, 11.","DOI":"10.3390\/coatings11040381"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"31765","DOI":"10.1039\/D0RA05448H","article-title":"Biophotonic sensor for the detection of creatinine concentration in blood serum based on 1D photonic crystal","volume":"10","author":"Arafa","year":"2020","journal-title":"RSC Adv."}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/23\/16\/7122\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T20:31:46Z","timestamp":1760128306000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/23\/16\/7122"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,11]]},"references-count":33,"journal-issue":{"issue":"16","published-online":{"date-parts":[[2023,8]]}},"alternative-id":["s23167122"],"URL":"https:\/\/doi.org\/10.3390\/s23167122","relation":{},"ISSN":["1424-8220"],"issn-type":[{"value":"1424-8220","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,11]]}}}