{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T22:59:49Z","timestamp":1774306789732,"version":"3.50.1"},"reference-count":98,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T00:00:00Z","timestamp":1692230400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"POR-FESR 2014-2020 REGIONE EMILIA ROMAGNA","award":["E91B20000280007"],"award-info":[{"award-number":["E91B20000280007"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Background: \u201cRicominciare\u201d is a single-center, prospective, pre-\/post-intervention pilot study aimed at verifying the feasibility and safety of the ARC Intellicare (ARC) system (an artificial intelligence-powered and inertial motion unit-based mobile platform) in the home rehabilitation of people with disabilities due to respiratory or neurological diseases. Methods. People with Parkinson\u2019s disease (pwPD) or post-COVID-19 condition (COV19) and an indication for exercise or home rehabilitation to optimize motor and respiratory function were enrolled. They underwent training for ARC usage and received an ARC unit to be used independently at home for 4 weeks, for 45 min 5 days\/week sessions of respiratory and motor patient-tailored rehabilitation. ARC allows for exercise monitoring thanks to data from five IMU sensors, processed by an AI proprietary library to provide (i) patients with real-time feedback and (ii) therapists with information on patient adherence to the prescribed therapy. Usability (System Usability Scale, SUS), adherence, and adverse events were primary study outcomes. Modified Barthel Index (mBI), Barthel Dyspnea Index (BaDI), 2-Minute Walking Test (2MWT), Brief Fatigue Inventory (BFI), Beck Depression or Anxiety Inventory (BDI, BAI), and quality of life (EQ-5D) were also monitored pre- and post-treatment. Results. A total of 21 out of 23 eligible patients were enrolled and completed the study: 11 COV19 and 10 pwPD. The mean total SUS score was 77\/100. The median patients\u2019 adherence to exercise prescriptions was 80%. Clinical outcome measures (BaDI, 2MWT distance, BFI; BAI, BDI, and EQ-5D) improved significantly; no side effects were reported. Conclusion. ARC is usable and safe for home rehabilitation. Preliminary data suggest promising results on the effectiveness in subjects with post-COVID condition or Parkinson\u2019s disease.<\/jats:p>","DOI":"10.3390\/s23167238","type":"journal-article","created":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T10:28:48Z","timestamp":1692354528000},"page":"7238","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Telerehabilitation with ARC Intellicare to Cope with Motor and Respiratory Disabilities: Results about the Process, Usability, and Clinical Effect of the \u201cRicominciare\u201d Pilot Study"],"prefix":"10.3390","volume":"23","author":[{"given":"Marianna","family":"Capecci","sequence":"first","affiliation":[{"name":"Department of Experimental and Clinical Medicine, Polytechnic University of Marche, 60121 Ancona, Italy"}]},{"given":"Rossella","family":"Cima","sequence":"additional","affiliation":[{"name":"Department of Experimental and Clinical Medicine, Polytechnic University of Marche, 60121 Ancona, Italy"}]},{"given":"Filippo A.","family":"Barbini","sequence":"additional","affiliation":[{"name":"Department of Experimental and Clinical Medicine, Polytechnic University of Marche, 60121 Ancona, Italy"}]},{"given":"Alice","family":"Mantoan","sequence":"additional","affiliation":[{"name":"Henesis Division, Camlin Italy Srl, 43123 Parma, Italy"}]},{"given":"Francesca","family":"Sernissi","sequence":"additional","affiliation":[{"name":"Henesis Division, Camlin Italy Srl, 43123 Parma, Italy"}]},{"given":"Stefano","family":"Lai","sequence":"additional","affiliation":[{"name":"Henesis Division, Camlin Italy Srl, 43123 Parma, Italy"}]},{"given":"Riccardo","family":"Fava","sequence":"additional","affiliation":[{"name":"Henesis Division, Camlin Italy Srl, 43123 Parma, Italy"}]},{"given":"Luca","family":"Tagliapietra","sequence":"additional","affiliation":[{"name":"Henesis Division, Camlin Italy Srl, 43123 Parma, Italy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0956-1598","authenticated-orcid":false,"given":"Luca","family":"Ascari","sequence":"additional","affiliation":[{"name":"Henesis Division, Camlin Italy Srl, 43123 Parma, Italy"}]},{"given":"Roberto N.","family":"Izzo","sequence":"additional","affiliation":[{"name":"Department of Experimental and Clinical Medicine, Polytechnic University of Marche, 60121 Ancona, Italy"}]},{"given":"Maria Eleonora","family":"Leombruni","sequence":"additional","affiliation":[{"name":"Department of Experimental and Clinical Medicine, Polytechnic University of Marche, 60121 Ancona, Italy"}]},{"given":"Paola","family":"Casoli","sequence":"additional","affiliation":[{"name":"Department of Experimental and Clinical Medicine, Polytechnic University of Marche, 60121 Ancona, Italy"}]},{"given":"Margherita","family":"Hibel","sequence":"additional","affiliation":[{"name":"Department of Experimental and Clinical Medicine, Polytechnic University of Marche, 60121 Ancona, Italy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2694-4638","authenticated-orcid":false,"given":"Maria Gabriella","family":"Ceravolo","sequence":"additional","affiliation":[{"name":"Department of Experimental and Clinical Medicine, Polytechnic University of Marche, 60121 Ancona, Italy"}]}],"member":"1968","published-online":{"date-parts":[[2023,8,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2006","DOI":"10.1016\/S0140-6736(20)32340-0","article-title":"Global estimates of the need for rehabilitation based on the Global Burden of Disease study 2019: A systematic analysis for the Global Burden of Disease Study 2019","volume":"396","author":"Cieza","year":"2021","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2763","DOI":"10.2147\/COPD.S144571","article-title":"Estimating the effectiveness of pulmonary rehabilitation for COPD exacerbations: Reduction of hospital inpatient days during the following year","volume":"12","author":"Katajisto","year":"2017","journal-title":"Int. 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