{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T03:45:13Z","timestamp":1770522313788,"version":"3.49.0"},"reference-count":51,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T00:00:00Z","timestamp":1694995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Background: Dynamic mechanical allodynia (DMA) is both a symptom and a central sensitization sign, yet no standardized method for quantifying the DMA area has been reported. This study aimed to establish psychometric properties for Quantitative Dynamic Allodynography (QDA), a newly developed protocol measuring the DMA area as a percentage of the body surface. Methods: Seventy-eight patients aged 18\u201365 diagnosed with chronic complex regional pain syndrome (CRPS) participated in this study. Test\u2013retest reliability was conducted twice, one week apart (N = 20), and inter-rater (N = 3) reliability was conducted on 10 participants. Disease severity (CRPS Severity Score, CSS), pain intensity (VAS), and quality of life (SF-36) measures were utilized to test construct validity. Results: High inter-rater reliability (intraclass correlation coefficient (ICC) = 0.96, p &lt; 0.001) and test\u2013retest reliability (r = 0.98, p &lt; 0.001) were found. Furthermore, the QDA score was found to be correlated with the CSS (r = 0.47, p &lt; 0.001), VAS (r = 0.37, p &lt; 0.001), and the SF-36 physical health total (r = \u22120.47, p &lt; 0.001) scores. Conclusion: The QDA is the first developed reliable and valid protocol for measuring DMA in a clinical setting and may be used as a diagnostic and prognostic measure in clinics and in research, advancing the pain precision medicine approach.<\/jats:p>","DOI":"10.3390\/s23187949","type":"journal-article","created":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T02:17:30Z","timestamp":1695003450000},"page":"7949","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Quantitative Dynamic Allodynograph\u2014A Standardized Measure for Testing Dynamic Mechanical Allodynia in Chronic Limb Pain"],"prefix":"10.3390","volume":"23","author":[{"given":"Noy","family":"Turgeman Dahan","sequence":"first","affiliation":[{"name":"Department of Occupational Therapy, School of Health Professions, Faculty of Medicine, Tel Aviv University, Tel Aviv-Yafo 69978, Israel"},{"name":"Reuth Rehabilitation Hospital, Tel Aviv-Yafo 6772830, Israel"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9473-2979","authenticated-orcid":false,"given":"Jean-Jacques","family":"Vatine","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Tel Aviv University, Tel Aviv-Yafo 69978, Israel"}]},{"given":"Irit","family":"Weissman-Fogel","sequence":"additional","affiliation":[{"name":"Physical Therapy Department, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa 3103301, Israel"}]},{"given":"Hana","family":"Karpin","sequence":"additional","affiliation":[{"name":"Reuth Rehabilitation Hospital, Tel Aviv-Yafo 6772830, Israel"},{"name":"Physical Therapy Department, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa 3103301, Israel"}]},{"given":"Sharon","family":"Shmuely","sequence":"additional","affiliation":[{"name":"Reuth Rehabilitation Hospital, Tel Aviv-Yafo 6772830, Israel"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1494-2640","authenticated-orcid":false,"given":"Tami","family":"Bar-Shalita","sequence":"additional","affiliation":[{"name":"Department of Occupational Therapy, School of Health Professions, Faculty of Medicine, Tel Aviv University, Tel Aviv-Yafo 69978, Israel"}]}],"member":"1968","published-online":{"date-parts":[[2023,9,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/0304-3959(92)90262-A","article-title":"Dynamic and static components of mechanical hyperalgesia in human hairy skin","volume":"51","author":"Koltzenburg","year":"1992","journal-title":"Pain"},{"key":"ref_2","first-page":"465","article-title":"Mechanical hyperalgesias in neuropathic pain patients: Dynamic and static subtypes","volume":"33","author":"Ochoa","year":"1993","journal-title":"Ann. 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