{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T16:40:51Z","timestamp":1774629651442,"version":"3.50.1"},"reference-count":57,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2023,11,9]],"date-time":"2023-11-09T00:00:00Z","timestamp":1699488000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"JAEB Centre for Health Research"},{"name":"Ontario Graduate Scholarship"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>The impact of age, sex and body mass index on interstitial glucose levels as measured via continuous glucose monitoring (CGM) during exercise in the healthy population is largely unexplored. We conducted a multivariable generalized estimating equation (GEE) analysis on CGM data (Dexcom G6, 10 days) collected from 119 healthy exercising individuals using CGM with the following specified covariates: age; sex; BMI; exercise type and duration. Females had lower postexercise glycemia as compared with males (92 \u00b1 18 vs. 100 \u00b1 20 mg\/dL, p = 0.04) and a greater change in glycemia during exercise from pre- to postexercise (p = 0.001) or from pre-exercise to glucose nadir during exercise (p = 0.009). Younger individuals (i.e., &lt;20 yrs) had higher glucose during exercise as compared with all other age groups (all p &lt; 0.05) and less CGM data in the hypoglycemic range (&lt;70 mg\/dL) as compared with those aged 20\u201339 yrs (p &lt; 0.05). Those who were underweight, based on body mass index (BMI: &lt;18.5 kg\/m2), had higher pre-exercise glycemia than the healthy BMI group (104 \u00b1 20 vs. 97 \u00b1 17 mg\/dL, p = 0.02) but similar glucose levels after exercise. Resistance exercise was associated with less of a drop in glycemia as compared with aerobic or mixed forms of exercise (p = 0.008) and resulted in a lower percent of time in the hypoglycemic (p = 0.04) or hyperglycemic (glucose &gt; 140 mg\/dL) (p = 0.03) ranges. In summary, various factors such as age, sex and exercise type appear to have subtle but potentially important influence on CGM measurements during exercise in healthy individuals.<\/jats:p>","DOI":"10.3390\/s23229059","type":"journal-article","created":{"date-parts":[[2023,11,9]],"date-time":"2023-11-09T03:42:40Z","timestamp":1699501360000},"page":"9059","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["The Impact of Sex, Body Mass Index, Age, Exercise Type and Exercise Duration on Interstitial Glucose Levels during Exercise"],"prefix":"10.3390","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2178-373X","authenticated-orcid":false,"given":"Ninoschka C.","family":"D\u2019Souza","sequence":"first","affiliation":[{"name":"School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, ON M3J 1P3, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Durmalouk","family":"Kesibi","sequence":"additional","affiliation":[{"name":"School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, ON M3J 1P3, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Yeung","sequence":"additional","affiliation":[{"name":"School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, ON M3J 1P3, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorsa","family":"Shakeri","sequence":"additional","affiliation":[{"name":"School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, ON M3J 1P3, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7486-6956","authenticated-orcid":false,"given":"Ashwin I.","family":"D\u2019Souza","sequence":"additional","affiliation":[{"name":"The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alison K.","family":"Macpherson","sequence":"additional","affiliation":[{"name":"School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, ON M3J 1P3, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6556-7559","authenticated-orcid":false,"given":"Michael C.","family":"Riddell","sequence":"additional","affiliation":[{"name":"School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, ON M3J 1P3, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,11,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Brooks, G.A. 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