{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T23:08:26Z","timestamp":1779145706638,"version":"3.51.4"},"reference-count":254,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2023,11,29]],"date-time":"2023-11-29T00:00:00Z","timestamp":1701216000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Disease diagnosis and monitoring using conventional healthcare services is typically expensive and has limited accuracy. Wearable health technology based on flexible electronics has gained tremendous attention in recent years for monitoring patient health owing to attractive features, such as lower medical costs, quick access to patient health data, ability to operate and transmit data in harsh environments, storage at room temperature, non-invasive implementation, mass scaling, etc. This technology provides an opportunity for disease pre-diagnosis and immediate therapy. Wearable sensors have opened a new area of personalized health monitoring by accurately measuring physical states and biochemical signals. Despite the progress to date in the development of wearable sensors, there are still several limitations in the accuracy of the data collected, precise disease diagnosis, and early treatment. This necessitates advances in applied materials and structures and using artificial intelligence (AI)-enabled wearable sensors to extract target signals for accurate clinical decision-making and efficient medical care. In this paper, we review two significant aspects of smart wearable sensors. First, we offer an overview of the most recent progress in improving wearable sensor performance for physical, chemical, and biosensors, focusing on materials, structural configurations, and transduction mechanisms. Next, we review the use of AI technology in combination with wearable technology for big data processing, self-learning, power-efficiency, real-time data acquisition and processing, and personalized health for an intelligent sensing platform. Finally, we present the challenges and future opportunities associated with smart wearable sensors.<\/jats:p>","DOI":"10.3390\/s23239498","type":"journal-article","created":{"date-parts":[[2023,11,30]],"date-time":"2023-11-30T00:34:10Z","timestamp":1701304450000},"page":"9498","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":419,"title":["The Emergence of AI-Based Wearable Sensors for Digital Health Technology: A Review"],"prefix":"10.3390","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2512-3571","authenticated-orcid":false,"given":"Shaghayegh","family":"Shajari","sequence":"first","affiliation":[{"name":"Center for Applied Polymers and Nanotechnology (CAPNA), Department of Chemical and Petroleum Engineering, University of Calgary, Calgary, AB T2N1 N4, Canada"},{"name":"Center for Bio-Integrated Electronics (CBIE), Querrey Simpson Institute for Bioelectronics (QSIB), Northwestern University, Evanston, IL 60208, USA"}]},{"given":"Kirankumar","family":"Kuruvinashetti","sequence":"additional","affiliation":[{"name":"Intelligent Human and Animal Assistive Devices, Department of Biomedical Engineering, University of Calgary, Calgary, AB T2N 1N4, Canada"},{"name":"Department of Mechanical and Manufacturing Engineering, University of Calgary, Calgary, AB T2N 1N4, Canada"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0938-6099","authenticated-orcid":false,"given":"Amin","family":"Komeili","sequence":"additional","affiliation":[{"name":"Intelligent Human and Animal Assistive Devices, Department of Biomedical Engineering, University of Calgary, Calgary, AB T2N 1N4, Canada"},{"name":"Department of Mechanical and Manufacturing Engineering, University of Calgary, Calgary, AB T2N 1N4, Canada"}]},{"given":"Uttandaraman","family":"Sundararaj","sequence":"additional","affiliation":[{"name":"Center for Applied Polymers and Nanotechnology (CAPNA), Department of Chemical and Petroleum Engineering, University of Calgary, Calgary, AB T2N1 N4, Canada"}]}],"member":"1968","published-online":{"date-parts":[[2023,11,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"4043","DOI":"10.1039\/C8TB01063C","article-title":"Wearable and flexible sensors for user-interactive health-monitoring devices","volume":"6","author":"Ha","year":"2018","journal-title":"J. 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