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Here, we demonstrate that the Nb2CTz-based sensor exhibits high performance towards alcohol vapors at temperatures up to 300\u2013350 \u00b0C, with the best sensitivity towards ethanol. We attribute the observed remarkable chemiresistive effect of this material to the formation of quasi-2D Nb2O5 sheets as the result of the oxidation of Nb-based MXenes. These findings are supported by synchrotron X-ray photoelectron spectroscopy studies together with X-ray diffraction and electron microscopy observations. For analyte selectivity, we employ a multisensor approach where the gas recognition is achieved by linear discriminant analysis of the vector response of the on-chip sensor array. The reported protocol demonstrates that MXene layers are efficient precursors for the derivation of 2D oxide architectures, which are suitable for developing gas sensors and sensor arrays.<\/jats:p>","DOI":"10.3390\/s24010038","type":"journal-article","created":{"date-parts":[[2023,12,20]],"date-time":"2023-12-20T11:24:33Z","timestamp":1703071473000},"page":"38","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Alcohol Vapor Sensor Based on Quasi-2D Nb2O5 Derived from Oxidized Nb2CTz MXenes"],"prefix":"10.3390","volume":"24","author":[{"given":"Hanna","family":"Pazniak","sequence":"first","affiliation":[{"name":"Laboratoire des Mat\u00e9riaux et du G\u00e9nie Physique, Institut Polytechnique de Grenoble, Centre National de la Recherche Scientifique, Universit\u00e9 Grenoble Alpes, CS 50257, 38016 Grenoble, Cedex 1, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1066-1596","authenticated-orcid":false,"given":"Ilya A.","family":"Plugin","sequence":"additional","affiliation":[{"name":"Physico-Technical Institute, Yuri Gagarin State Technical University of Saratov, ul. 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