{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T21:36:29Z","timestamp":1767908189064,"version":"3.49.0"},"reference-count":52,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2023,12,29]],"date-time":"2023-12-29T00:00:00Z","timestamp":1703808000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"PATHOS EU H2020 FET-OPEN","award":["828946"],"award-info":[{"award-number":["828946"]}]},{"name":"PATHOS EU H2020 FET-OPEN","award":["20IND05"],"award-info":[{"award-number":["20IND05"]}]},{"name":"PATHOS EU H2020 FET-OPEN","award":["ERA.NET II-BIOMB"],"award-info":[{"award-number":["ERA.NET II-BIOMB"]}]},{"name":"EMPIR","award":["828946"],"award-info":[{"award-number":["828946"]}]},{"name":"EMPIR","award":["20IND05"],"award-info":[{"award-number":["20IND05"]}]},{"name":"EMPIR","award":["ERA.NET II-BIOMB"],"award-info":[{"award-number":["ERA.NET II-BIOMB"]}]},{"DOI":"10.13039\/501100003407","name":"MIUR","doi-asserted-by":"publisher","award":["828946"],"award-info":[{"award-number":["828946"]}],"id":[{"id":"10.13039\/501100003407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003407","name":"MIUR","doi-asserted-by":"publisher","award":["20IND05"],"award-info":[{"award-number":["20IND05"]}],"id":[{"id":"10.13039\/501100003407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003407","name":"MIUR","doi-asserted-by":"publisher","award":["ERA.NET II-BIOMB"],"award-info":[{"award-number":["ERA.NET II-BIOMB"]}],"id":[{"id":"10.13039\/501100003407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>The present paper reports on a Finite Element Method (FEM) analysis of the experimental situation corresponding to the measurement of the temperature variation in a single cell plated on bulk diamond by means of optical techniques. Starting from previous experimental results, we have determined\u2014in a uniform power density approximation and under steady-state conditions\u2014the total heat power that has to be dissipated by a single cell plated on a glassy substrate in order to induce the typical maximum temperature increase \u0394Tglass=1 K. While keeping all of the other parameters constant, the glassy substrate has been replaced by a diamond plate. The FEM analysis shows that, in this case, the maximum temperature increase is expected at the diamond\/cell interface and is as small as \u0394Tdiam=4.6\u00d710\u22124 K. We have also calculated the typical decay time in the transient scenario, which resulted in \u03c4\u2248 250 \u03bcs. By comparing these results with the state-of-the-art sensitivity values, we prove that the potential advantages of a longer coherence time, better spectral properties, and the use of special field alignments do not justify the use of diamond substrates in their bulk form.<\/jats:p>","DOI":"10.3390\/s24010200","type":"journal-article","created":{"date-parts":[[2023,12,29]],"date-time":"2023-12-29T03:28:41Z","timestamp":1703820521000},"page":"200","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Limitations of Bulk Diamond Sensors for Single-Cell Thermometry"],"prefix":"10.3390","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-8879-5617","authenticated-orcid":false,"given":"Andrea","family":"Alessio","sequence":"first","affiliation":[{"name":"Physics Department, University of Turin, Via P. Giuria 1, 10125 Turin, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0397-7397","authenticated-orcid":false,"given":"Ettore","family":"Bernardi","sequence":"additional","affiliation":[{"name":"Istituto Nazionale di Ricerca Metrologica, Strada delle Cacce 91, 10135 Turin, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6792-8386","authenticated-orcid":false,"given":"Ekaterina","family":"Moreva","sequence":"additional","affiliation":[{"name":"Istituto Nazionale di Ricerca Metrologica, Strada delle Cacce 91, 10135 Turin, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0332-3115","authenticated-orcid":false,"given":"Ivo Pietro","family":"Degiovanni","sequence":"additional","affiliation":[{"name":"Istituto Nazionale di Ricerca Metrologica, Strada delle Cacce 91, 10135 Turin, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9186-8849","authenticated-orcid":false,"given":"Marco","family":"Genovese","sequence":"additional","affiliation":[{"name":"Istituto Nazionale di Ricerca Metrologica, Strada delle Cacce 91, 10135 Turin, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1564-221X","authenticated-orcid":false,"given":"Marco","family":"Truccato","sequence":"additional","affiliation":[{"name":"Physics Department, University of Turin, Via P. 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