{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:38:17Z","timestamp":1760143097532,"version":"build-2065373602"},"reference-count":41,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2024,1,22]],"date-time":"2024-01-22T00:00:00Z","timestamp":1705881600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Istituto Nazionale di Fisica Nucleare (INFN)"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>We assessed the accuracy of a prototype radiation detector with a built in CMOS amplifier for use in dosimetry for high dose rate brachytherapy. The detectors were fabricated on two substrates of epitaxial high resistivity silicon. The radiation detection performance of prototypes has been tested by ion beam induced charge (IBIC) microscopy using a 5.5 MeV alpha particle microbeam. We also carried out the HDR Ir-192 radiation source tracking at different depths and angular dose dependence in a water equivalent phantom. The detectors show sensitivities spanning from (5.8 \u00b1 0.021) \u00d7 10\u22128 to (3.6 \u00b1 0.14) \u00d7 10\u22128 nC Gy\u22121 mCi\u22121 mm\u22122. The depth variation of the dose is within 5% with that calculated by TG-43. Higher discrepancies are recorded for 2 mm and 7 mm depths due to the scattering of secondary particles and the perturbation of the radiation field induced in the ceramic\/golden package. Dwell positions and dwell time are reconstructed within \u00b11 mm and 20 ms, respectively. The prototype detectors provide an unprecedented sensitivity thanks to its monolithic amplification stage. Future investigation of this technology will include the optimisation of the packaging technique.<\/jats:p>","DOI":"10.3390\/s24020692","type":"journal-article","created":{"date-parts":[[2024,1,22]],"date-time":"2024-01-22T12:01:13Z","timestamp":1705924873000},"page":"692","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Preliminary Characterization of an Active CMOS Pad Detector for Tracking and Dosimetry in HDR Brachytherapy"],"prefix":"10.3390","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7486-5363","authenticated-orcid":false,"given":"Thi Ngoc Hang","family":"Bui","sequence":"first","affiliation":[{"name":"Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW 2522, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Large","sequence":"additional","affiliation":[{"name":"Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW 2522, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9187-2618","authenticated-orcid":false,"given":"Joel","family":"Poder","sequence":"additional","affiliation":[{"name":"Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW 2522, Australia"},{"name":"St George Cancer Care Centre, Kogarah, NSW 2217, Australia"},{"name":"School of Physics, University of Sydney, Camperdown, NSW 2050, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Bucci","sequence":"additional","affiliation":[{"name":"Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW 2522, Australia"},{"name":"St George Cancer Care Centre, Kogarah, NSW 2217, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edoardo","family":"Bianco","sequence":"additional","affiliation":[{"name":"Department of Electronics and Telecommunications, Polytechnic University of Turin, 10129 Turin, Italy"},{"name":"Istituto Nazionale di Fisica Nucleare\u2014Section of Turin, 10125 Turin, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5036-7810","authenticated-orcid":false,"given":"Raffaele Aaron","family":"Giampaolo","sequence":"additional","affiliation":[{"name":"Department of Electronics and Telecommunications, Polytechnic University of Turin, 10129 Turin, Italy"},{"name":"Istituto Nazionale di Fisica Nucleare\u2014Section of Turin, 10125 Turin, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelo","family":"Rivetti","sequence":"additional","affiliation":[{"name":"Istituto Nazionale di Fisica Nucleare\u2014Section of Turin, 10125 Turin, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Da Rocha Rolo","sequence":"additional","affiliation":[{"name":"Istituto Nazionale di Fisica Nucleare\u2014Section of Turin, 10125 Turin, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeljko","family":"Pastuovic","sequence":"additional","affiliation":[{"name":"Australian Nuclear Science and Technology Organisation, Lucas Heights, NSW 2234, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0236-6834","authenticated-orcid":false,"given":"Thomas","family":"Corradino","sequence":"additional","affiliation":[{"name":"Department of Industrial Engineering, University of Trento, 38123 Trento, Italy"},{"name":"Trento Institute for Fundamental Physics and Applications, Istituto Nazionale di Fisica Nucleare, 38123 Trento, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3954-7308","authenticated-orcid":false,"given":"Lucio","family":"Pancheri","sequence":"additional","affiliation":[{"name":"Department of Industrial Engineering, University of Trento, 38123 Trento, Italy"},{"name":"Trento Institute for Fundamental Physics and Applications, Istituto Nazionale di Fisica Nucleare, 38123 Trento, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5958-7457","authenticated-orcid":false,"given":"Marco","family":"Petasecca","sequence":"additional","affiliation":[{"name":"Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW 2522, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,1,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e1450","DOI":"10.1002\/cnr2.1450","article-title":"High-dose-rate brachytherapy for prostate cancer: Rationale, current applications, and clinical outcome","volume":"5","author":"Strouthos","year":"2022","journal-title":"Cancer Rep."},{"key":"ref_2","first-page":"1","article-title":"Prevention of high-dose-rate brachytherapy accidents. 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