{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T17:01:28Z","timestamp":1778605288962,"version":"3.51.4"},"reference-count":101,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2024,3,24]],"date-time":"2024-03-24T00:00:00Z","timestamp":1711238400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"the State Key Program of National Natural Science of China","award":["22134007"],"award-info":[{"award-number":["22134007"]}]},{"name":"the State Key Program of National Natural Science of China","award":["22076223"],"award-info":[{"award-number":["22076223"]}]},{"name":"the State Key Program of National Natural Science of China","award":["22376225"],"award-info":[{"award-number":["22376225"]}]},{"name":"the State Key Program of National Natural Science of China","award":["2022A1515011390"],"award-info":[{"award-number":["2022A1515011390"]}]},{"name":"the State Key Program of National Natural Science of China","award":["2024A1515011548"],"award-info":[{"award-number":["2024A1515011548"]}]},{"name":"the National Natural Science Foundation of China","award":["22134007"],"award-info":[{"award-number":["22134007"]}]},{"name":"the National Natural Science Foundation of China","award":["22076223"],"award-info":[{"award-number":["22076223"]}]},{"name":"the National Natural Science Foundation of China","award":["22376225"],"award-info":[{"award-number":["22376225"]}]},{"name":"the National Natural Science Foundation of China","award":["2022A1515011390"],"award-info":[{"award-number":["2022A1515011390"]}]},{"name":"the National Natural Science Foundation of China","award":["2024A1515011548"],"award-info":[{"award-number":["2024A1515011548"]}]},{"name":"Guangdong Basic and Applied Basic Research Foundation","award":["22134007"],"award-info":[{"award-number":["22134007"]}]},{"name":"Guangdong Basic and Applied Basic Research Foundation","award":["22076223"],"award-info":[{"award-number":["22076223"]}]},{"name":"Guangdong Basic and Applied Basic Research Foundation","award":["22376225"],"award-info":[{"award-number":["22376225"]}]},{"name":"Guangdong Basic and Applied Basic Research Foundation","award":["2022A1515011390"],"award-info":[{"award-number":["2022A1515011390"]}]},{"name":"Guangdong Basic and Applied Basic Research Foundation","award":["2024A1515011548"],"award-info":[{"award-number":["2024A1515011548"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>This review introduces a micro-integrated device of microfluidics and fiber-optic sensors for on-site detection, which can detect certain or several specific components or their amounts in different samples within a relatively short time. Fiber-optics with micron core diameters can be easily coated and functionalized, thus allowing sensors to be integrated with microfluidics to separate, enrich, and measure samples in a micro-device. Compared to traditional laboratory equipment, this integrated device exhibits natural advantages in size, speed, cost, portability, and operability, making it more suitable for on-site detection. In this review, the various optical detection methods used in this integrated device are introduced, including Raman, ultraviolet\u2013visible, fluorescence, and surface plasmon resonance detections. It also provides a detailed overview of the on-site detection applications of this integrated device for biological analysis, food safety, and environmental monitoring. Lastly, this review addresses the prospects for the future development of microfluidics integrated with fiber-optic sensors.<\/jats:p>","DOI":"10.3390\/s24072067","type":"journal-article","created":{"date-parts":[[2024,3,25]],"date-time":"2024-03-25T12:32:36Z","timestamp":1711369956000},"page":"2067","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Recent Progress on Microfluidics Integrated with Fiber-Optic Sensors for On-Site Detection"],"prefix":"10.3390","volume":"24","author":[{"given":"Weibin","family":"Wang","sequence":"first","affiliation":[{"name":"School of Chemistry, Sun Yat-sen University, Guangzhou 510006, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling","family":"Xia","sequence":"additional","affiliation":[{"name":"School of Chemistry, Sun Yat-sen University, Guangzhou 510006, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaohua","family":"Xiao","sequence":"additional","affiliation":[{"name":"School of Chemistry, Sun Yat-sen University, Guangzhou 510006, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3750-6358","authenticated-orcid":false,"given":"Gongke","family":"Li","sequence":"additional","affiliation":[{"name":"School of Chemistry, Sun Yat-sen University, Guangzhou 510006, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,3,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"108692","DOI":"10.1016\/j.microc.2023.108692","article-title":"Smartphone-assisted microfluidic sensor as an intelligent device for on-site determination of food contaminants: Developments and applications","volume":"190","author":"Khalaf","year":"2023","journal-title":"Microchem. 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