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Fortunately, the emerging paradigms of near-sensor and in-sensor computing, together with the proposal of flexible neuromorphic devices, provides a viable solution for the application of intelligent low-power wearable devices. Therefore, wearable smart systems based on new computing paradigms are of great research value. This review discusses the research status of a flexible five-sense sensing system based on near-sensor and in-sensor architectures, considering material design, structural design and circuit design. Furthermore, we summarize challenging problems that need to be solved and provide an outlook on the potential applications of intelligent wearable devices.<\/jats:p>","DOI":"10.3390\/s24072180","type":"journal-article","created":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T12:22:46Z","timestamp":1711628566000},"page":"2180","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Recent Progress in Wearable Near-Sensor and In-Sensor Intelligent Perception Systems"],"prefix":"10.3390","volume":"24","author":[{"given":"Jialin","family":"Liu","sequence":"first","affiliation":[{"name":"CAS Key Laboratory of Magnetic Materials and Devices, Zhejiang Province Key Laboratory of Magnetic Materials and Application Technology, Ningbo Institute of Materials Technology and Engineering, China Academy of Sciences, Ningbo 315201, China"},{"name":"College of Materials Science and Opto-Electronic Technology, University of China Academy of Sciences, Beijing 100049, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yitao","family":"Wang","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Magnetic Materials and Devices, Zhejiang Province Key Laboratory of Magnetic Materials and Application Technology, Ningbo Institute of Materials Technology and Engineering, China Academy of Sciences, Ningbo 315201, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiwei","family":"Liu","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Magnetic Materials and Devices, Zhejiang Province Key Laboratory of Magnetic Materials and Application Technology, Ningbo Institute of Materials Technology and Engineering, China Academy of Sciences, Ningbo 315201, China"},{"name":"College of Materials Science and Opto-Electronic Technology, University of China Academy of Sciences, Beijing 100049, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuanzhao","family":"Wu","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Magnetic Materials and Devices, Zhejiang Province Key Laboratory of Magnetic Materials and Application Technology, Ningbo Institute of Materials Technology and Engineering, China Academy of Sciences, Ningbo 315201, China"},{"name":"College of Materials Science and Opto-Electronic Technology, University of China Academy of Sciences, Beijing 100049, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baoru","family":"Bian","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Magnetic Materials and Devices, Zhejiang Province Key Laboratory of Magnetic Materials and Application Technology, Ningbo Institute of Materials Technology and Engineering, China Academy of Sciences, Ningbo 315201, China"},{"name":"College of Materials Science and Opto-Electronic Technology, University of China Academy of Sciences, Beijing 100049, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0996-1038","authenticated-orcid":false,"given":"Jie","family":"Shang","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Magnetic Materials and Devices, Zhejiang Province Key Laboratory of Magnetic Materials and Application Technology, Ningbo Institute of Materials Technology and Engineering, China Academy of Sciences, Ningbo 315201, China"},{"name":"College of Materials Science and Opto-Electronic Technology, University of China Academy of Sciences, Beijing 100049, China"},{"name":"Materials and Optoelectronics Research Center, University of Chinese Academy of Sciences, Beijing 100049, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Runwei","family":"Li","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Magnetic Materials and Devices, Zhejiang Province Key Laboratory of Magnetic Materials and Application Technology, Ningbo Institute of Materials Technology and Engineering, China Academy of Sciences, Ningbo 315201, China"},{"name":"College of Materials Science and Opto-Electronic Technology, University of China Academy of Sciences, Beijing 100049, China"},{"name":"Materials and Optoelectronics Research Center, University of Chinese Academy of Sciences, Beijing 100049, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,3,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1805921","DOI":"10.1002\/adma.201805921","article-title":"Significance of Nanomaterials in Wearables: A Review on Wearable Actuators and Sensors","volume":"31","author":"Jayathilaka","year":"2019","journal-title":"Adv. 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