{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T04:17:58Z","timestamp":1777868278590,"version":"3.51.4"},"reference-count":63,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2024,6,11]],"date-time":"2024-06-11T00:00:00Z","timestamp":1718064000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Healthcare is undergoing a fundamental shift in which digital health tools are becoming ubiquitous, with the promise of improved outcomes, reduced costs, and greater efficiency. Healthcare professionals, patients, and the wider public are faced with a paradox of choice regarding technologies across multiple domains. Research is continuing to look for methods and tools to further revolutionise all aspects of health from prediction, diagnosis, treatment, and monitoring. However, despite its promise, the reality of implementing digital health tools in practice, and the scalability of innovations, remains stunted. Digital health is approaching a crossroads where we need to shift our focus away from simply looking at developing new innovations to seriously considering how we overcome the barriers that currently limit its impact. This paper summarises over 10 years of digital health experiences from a group of researchers with backgrounds in physical therapy\u2014in order to highlight and discuss some of these key lessons\u2014in the areas of validity, patient and public involvement, privacy, reimbursement, and interoperability. Practical learnings from this collective experience across patient cohorts are leveraged to propose a list of recommendations to enable researchers to bridge the gap between the development and implementation of digital health tools.<\/jats:p>","DOI":"10.3390\/s24123780","type":"journal-article","created":{"date-parts":[[2024,6,11]],"date-time":"2024-06-11T12:11:00Z","timestamp":1718107860000},"page":"3780","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Breaking down the Digital Fortress: The Unseen Challenges in Healthcare Technology\u2014Lessons Learned from 10 Years of Research"],"prefix":"10.3390","volume":"24","author":[{"given":"Alison","family":"Keogh","sequence":"first","affiliation":[{"name":"Clinical Medicine, School of Medicine, Trinity College Dublin, Tallaght University Hospital, D24 TP66 Dublin, Ireland"},{"name":"Insight Centre for Data Analytics, University College Dublin, D04 V1W8 Dublin, Ireland"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3522-9409","authenticated-orcid":false,"given":"Rob","family":"Argent","sequence":"additional","affiliation":[{"name":"Insight Centre for Data Analytics, University College Dublin, D04 V1W8 Dublin, Ireland"},{"name":"School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine & Health Sciences, D02 YN77 Dublin, Ireland"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5284-856X","authenticated-orcid":false,"given":"Cailbhe","family":"Doherty","sequence":"additional","affiliation":[{"name":"Insight Centre for Data Analytics, University College Dublin, D04 V1W8 Dublin, Ireland"},{"name":"School of Public Health, Physiotherapy and Sports Science, University College Dublin, D04 V1W8 Dublin, Ireland"}]},{"given":"Ciara","family":"Duignan","sequence":"additional","affiliation":[{"name":"Insight Centre for Data Analytics, University College Dublin, D04 V1W8 Dublin, Ireland"}]},{"given":"Orna","family":"Fennelly","sequence":"additional","affiliation":[{"name":"Insight Centre for Data Analytics, University College Dublin, D04 V1W8 Dublin, Ireland"}]},{"given":"Ciaran","family":"Purcell","sequence":"additional","affiliation":[{"name":"Insight Centre for Data Analytics, University College Dublin, D04 V1W8 Dublin, Ireland"},{"name":"School of Allied Health, University of Limerick, V94 T9PX Limerick, Ireland"}]},{"given":"William","family":"Johnston","sequence":"additional","affiliation":[{"name":"Insight Centre for Data Analytics, University College Dublin, D04 V1W8 Dublin, Ireland"}]},{"given":"Brian","family":"Caulfield","sequence":"additional","affiliation":[{"name":"Insight Centre for Data Analytics, University College Dublin, D04 V1W8 Dublin, Ireland"},{"name":"School of Public Health, Physiotherapy and Sports Science, University College Dublin, D04 V1W8 Dublin, Ireland"}]}],"member":"1968","published-online":{"date-parts":[[2024,6,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Abernethy, A., Adams, L., Barrett, M., Bechtel, C., Brennan, P., Butte, A., Faulkner, J., Fontaine, E., Friedhoff, S., and Halamka, J. (2022). The Promise of Digital Health: Then, Now, and the Future. Natl. Acad. Med. Perspect.","DOI":"10.31478\/202206e"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1057\/sth.2013.10","article-title":"The digitally engaged patient: Self-monitoring and self-care in the digital health era","volume":"11","author":"Lupton","year":"2013","journal-title":"Soc. Theory Health"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1093\/qjmed\/hct114","article-title":"What is Connected Health and why will it change your practice?","volume":"106","author":"Caulfield","year":"2013","journal-title":"QJM"},{"key":"ref_4","unstructured":"Snowdon, A. (2020). Digital Health: A Framework for Healthcare Transformation, Healthcare Information and Management Systems Society."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.1109\/JPROC.2016.2615052","article-title":"Going Digital: A Survey on Digitalization and Large-Scale Data Analytics in Healthcare","volume":"104","author":"Tresp","year":"2016","journal-title":"Proc. IEEE"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"743","DOI":"10.3389\/fphys.2018.00743","article-title":"A Critical Review of Consumer Wearables, Mobile Applications, and Equipment for Providing Biofeedback, Monitoring Stress, and Sleep in Physically Active Populations","volume":"9","author":"Peake","year":"2018","journal-title":"Front. Physiol."},{"key":"ref_7","unstructured":"Samriddhi, C., and Roshan, D. (2022). Wearable Technology Market, Global Opportunity Analysis and Industry Forecast 2020\u20132031, Allied Market Research."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1001\/jama.2014.14781","article-title":"Wearable devices as facilitators, not drivers, of health behavior change","volume":"313","author":"Patel","year":"2015","journal-title":"JAMA"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"e11926","DOI":"10.2196\/11926","article-title":"Using Health and Well-Being Apps for Behavior Change: A Systematic Search and Rating of Apps","volume":"7","author":"McKay","year":"2019","journal-title":"JMIR mHealth uHealth"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"e11951","DOI":"10.2196\/11951","article-title":"Provider- and Patient-Related Barriers to and Facilitators of Digital Health Technology Adoption for Hypertension Management: Scoping Review","volume":"3","author":"Palacholla","year":"2019","journal-title":"JMIR Cardio"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"e24582","DOI":"10.2196\/24582","article-title":"Scale-up of Digital Innovations in Health Care: Expert Commentary on Enablers and Barriers","volume":"24","author":"Schlieter","year":"2022","journal-title":"J. Med. Internet Res."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"727421","DOI":"10.3389\/fdgth.2022.727421","article-title":"Making Digital Health \u201cSolutions\u201d Sustainable in Healthcare Systems: A Practitioner Perspective","volume":"4","author":"Cripps","year":"2022","journal-title":"Front. Digit. Health"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1249\/JES.0000000000000206","article-title":"A Framework to Evaluate Devices That Assess Physical Behavior","volume":"47","author":"Keadle","year":"2019","journal-title":"Exerc. Sport Sci. Rev."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1249\/JSR.0000000000000680","article-title":"Establishing a Global Standard for Wearable Devices in Sport and Fitness: Perspectives from the New England Chapter of the American College of Sports Medicine Members","volume":"19","author":"Ash","year":"2020","journal-title":"Curr. Sports Med. Rep."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Argent, R., Bevilacqua, A., Keogh, A., Daly, A., and Caulfield, B. (2021). The Importance of Real-World Validation of Machine Learning Systems in Wearable Exercise Biofeedback Platforms: A Case Study. Sensors, 21.","DOI":"10.3390\/s21072346"},{"key":"ref_16","first-page":"2055668319868544","article-title":"Evaluating the use of machine learning in the assessment of joint angle using a single inertial sensor","volume":"6","author":"Argent","year":"2019","journal-title":"J. Rehabil. Assist. Technol. Eng."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Argent, R., Slevin, P., Bevilacqua, A., Neligan, M., Daly, A., and Caulfield, B. (2019). Wearable Sensor-Based Exercise Biofeedback for Orthopaedic Rehabilitation: A Mixed Methods User Evaluation of a Prototype System. Sensors, 19.","DOI":"10.3390\/s19020432"},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Johnston, W., O\u2019Reilly, M., Dolan, K., Reid, N., Coughlan, G., and Caulfield, C. (2016, January 7\u20139). Objective classification of dynamic balance using a single wearable sensor. Proceedings of the 4th International Congress on Sport Sciences Research and Technology Support, Porto, Portugal.","DOI":"10.5220\/0006079400150024"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1136\/bjsports-2020-103147","article-title":"Recommendations for determining the validity of consumer wearable and smartphone step count: Expert statement and checklist of the INTERLIVE network","volume":"55","author":"Johnston","year":"2021","journal-title":"Br. J. Sports Med."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"e34257","DOI":"10.2196\/34257","article-title":"Human-Centered Design of a Digital Health Tool to Promote Effective Self-care in Patients With Heart Failure: Mixed Methods Study","volume":"6","author":"Johnston","year":"2022","journal-title":"JMIR Form. Res."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1159\/000485470","article-title":"Inertial Sensor Technology Can Capture Changes in Dynamic Balance Control during the Y Balance Test","volume":"1","author":"Johnston","year":"2017","journal-title":"Digit. Biomark."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1515\/bmt-2016-0120","article-title":"Validation and comparison of shank and lumbar-worn IMUs for step time estimation","volume":"62","author":"Johnston","year":"2017","journal-title":"Biomed. Eng. Biomed. Tech."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1080\/14763141.2017.1314544","article-title":"Classification of lunge biomechanics with multiple and individual inertial measurement units","volume":"16","author":"Whelan","year":"2017","journal-title":"Sports Biomech."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jbiomech.2017.04.028","article-title":"Classification of deadlift biomechanics with wearable inertial measurement units","volume":"58","author":"Whelan","year":"2017","journal-title":"J. Biomech."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"88","DOI":"10.3414\/ME16-02-0002","article-title":"Technology in Rehabilitation: Evaluating the Single Leg Squat Exercise with Wearable Inertial Measurement Units","volume":"56","author":"Whelan","year":"2017","journal-title":"Methods Inf. Med."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1186\/s12984-023-01198-5","article-title":"Assessing real-world gait with digital technology? Validation, insights and recommendations from the Mobilise-D consortium","volume":"20","author":"Bonci","year":"2023","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1159\/000512513","article-title":"A roadmap to inform development, validation and approval of digital mobility outcomes: The Mobilise-D approach","volume":"4","author":"Rochester","year":"2020","journal-title":"Digit. Biomark."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Doherty, C., Baldwin, M., Keogh, A., Caulfield, B., and Argent, R. (Sports Med., 2023). Keeping Pace with Wearables: A Living Systematic Umbrella Review of Systematic Reviews Evaluating the Accuracy of Commercial Wearable Technologies in Health Measurement, Sports Med., Under Review.","DOI":"10.31219\/osf.io\/s8kg5"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1136\/bjsports-2020-103148","article-title":"Recommendations for determining the validity of consumer wearable heart rate devices: Expert statement and checklist of the INTERLIVE Network","volume":"55","author":"Muhlen","year":"2021","journal-title":"Br. J. Sports Med."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1186\/s12984-021-00931-2","article-title":"Assessing the usability of wearable devices to measure gait and physical activity in chronic conditions: A systematic review","volume":"18","author":"Keogh","year":"2021","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"e15704","DOI":"10.2196\/15704","article-title":"Comparing the Usability and Acceptability of Wearable Sensors Among Older Irish Adults in a Real-World Context: Observational Study","volume":"8","author":"Keogh","year":"2020","journal-title":"JMIR mHealth uHealth"},{"key":"ref_32","first-page":"405","article-title":"Mobile athlete self-report measures and the complexities of implementation","volume":"18","author":"Duignan","year":"2019","journal-title":"J. Sports Sci. Med."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"3491","DOI":"10.1519\/JSC.0000000000003334","article-title":"Exploring the use of mobile athlete self-report measures in elite Gaelic games: A qualitative approach","volume":"35","author":"Duignan","year":"2021","journal-title":"J. Strength Cond. Res."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"e026326","DOI":"10.1136\/bmjopen-2018-026326","article-title":"Clinician perceptions of a prototype wearable exercise biofeedback system for orthopaedic rehabilitation: A qualitative exploration","volume":"8","author":"Argent","year":"2018","journal-title":"BMJ Open"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"e52442","DOI":"10.2196\/52442","article-title":"Six-month pilot testing of a digital health tool to support effective self-care in people with heart failure: A mixed methods study","volume":"8","author":"Keogh","year":"2023","journal-title":"JMIR Form. Res."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1159\/000512044","article-title":"\u201cIt\u2019s Not as Simple as Just Looking at One Chart\u201d: A Qualitative Study Exploring Clinician\u2019s Opinions on Various Visualisation Strategies to Represent Longitudinal Actigraphy Data","volume":"4","author":"Keogh","year":"2020","journal-title":"Digit. Biomark."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1186\/s12984-021-00874-8","article-title":"\u201cIt\u2019s not about the capture, it\u2019s about what we can learn\u201d: A qualitative study of experts\u2019 opinions and experiences regarding the use of wearable sensors to measure gait and physical activity","volume":"18","author":"Keogh","year":"2021","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1080\/09593985.2022.2042439","article-title":"Investigating the use of digital health tools in physiotherapy: Facilitators and barriers","volume":"39","author":"Keel","year":"2022","journal-title":"Physiother. Theory Pract."},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"van Berkel, N., Luo, C., Ferreira, D., Goncalves, J., and Kostakos, V. (2015, January 7\u201311). The Curse of the Quantified Self: An Endless Quest for Answers. Proceedings of the 2015 ACM International Joint Conference on Pervasive and Ubiquitous Computing and Proceedings of the 2015 ACM International Symposium on Wearable Computers\u2014UbiComp\u201915, Osaka, Japan.","DOI":"10.1145\/2800835.2800946"},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Kolasa, K., and Kozinski, G. (2020). How to Value Digital Health Interventions? A Systematic Literature Review. Int. J. Environ. Res. Public Health, 17.","DOI":"10.3390\/ijerph17062119"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"e44206","DOI":"10.2196\/44206","article-title":"Mobilizing Patient and Public Involvement in the Development of Real-World Digital Technology Solutions: Tutorial","volume":"25","author":"Keogh","year":"2023","journal-title":"J. Med. Internet Res."},{"key":"ref_42","unstructured":"Matwyshyn, A. (2017). CYBER!. BYU Law Rev., 6, Available online: https:\/\/digitalcommons.law.byu.edu\/lawreview\/vol2017\/iss5\/6."},{"key":"ref_43","unstructured":"Allen, A. (2019). Proceeding of the American Philosophical Assocation, American Philosophical Association."},{"key":"ref_44","first-page":"1908","article-title":"DASSL \u201cData Access Sharing Storage & Linkage\u201d Proof-of-Concept: Health and Related Data Linkage in Ireland","volume":"7","author":"Fennelly","year":"2022","journal-title":"Int. J. Popul. Data Sci."},{"key":"ref_45","unstructured":"Fennelly, O., Moriarty, F., Corrigan, D., Grogan, L., and Wong, S. (2022). Proof of Concept: Technical Prototype for Data Access Storage Sharing and Linkage DASSL to Support Research and Innovation in Ireland, Health Research Board."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"20552076221150745","DOI":"10.1177\/20552076221150745","article-title":"Acceptability of wearable devices for measuring mobility remotely: Observations from the Mobilise-D technical validation study","volume":"9","author":"Keogh","year":"2023","journal-title":"Digit. Health"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1002\/asi.24369","article-title":"\u201cTo protect my health or to protect my health privacy?\u201d A mixed-methods investigation of the privacy paradox","volume":"71","author":"Fox","year":"2020","journal-title":"J. Assoc. Inf. Sci. Technol."},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"Hirschprung, R.S. (2023). Is the Privacy Paradox a Domain-Specific Phenomenon. Computers, 12.","DOI":"10.3390\/computers12080156"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1080\/1369118X.2018.1486870","article-title":"The Biggest Lie on the Internet: Ignoring the Privacy Policies and Terms of Service Policies of Social Networking Services","volume":"23","author":"Obar","year":"2020","journal-title":"Inf. Commun. Soc."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1007\/s11948-013-9511-y","article-title":"Protecting human health and security in digital Europe: How to deal with the \u201cprivacy paradox\u201d?","volume":"20","author":"Buschel","year":"2014","journal-title":"Sci. Eng. Ethics"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1056\/NEJMp1011024","article-title":"What is value in health care?","volume":"363","author":"Porter","year":"2010","journal-title":"N. Engl. J. Med."},{"key":"ref_52","first-page":"20","article-title":"The sickening truth of the digital divide: Digital health reforms and digital inequality","volume":"12","author":"Stephens","year":"2021","journal-title":"J. Soc. Incl."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/s11524-020-00508-9","article-title":"The Expanding Digital Divide: Digital Health Access Inequities during the COVID-19 Pandemic in New York City","volume":"98","author":"Eruchalu","year":"2021","journal-title":"J. Urban Health"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"e204","DOI":"10.1016\/S2589-7500(19)30111-6","article-title":"Bridging the digital divide in health care","volume":"1","author":"Makri","year":"2019","journal-title":"Lancet Digit. Health"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"e395","DOI":"10.1016\/S2589-7500(20)30169-2","article-title":"COVID-19 and the digital divide in the UK","volume":"2","author":"Watts","year":"2020","journal-title":"Lancet Digit. Health"},{"key":"ref_56","doi-asserted-by":"crossref","unstructured":"Hadjiat, Y. (2023). Healthcare inequity and digital health\u2014A bridge for the divide, or further erosion of the chasm?. PLoS Digit. Health, 2.","DOI":"10.1371\/journal.pdig.0000268"},{"key":"ref_57","first-page":"72","article-title":"Effect of payment model on patient outcomes in outpatient physical therapy","volume":"47","author":"Charles","year":"2018","journal-title":"J. Allied Health"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"20552076211018617","DOI":"10.1177\/20552076211018617","article-title":"The NICE Evidence Standards Framework for digital health and care technologies\u2014Developing and maintaining an innovative evidence framework with global impact","volume":"7","author":"Unsworth","year":"2021","journal-title":"Digit. Health"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/s12962-022-00359-y","article-title":"Market access and value-based pricing of digital health applications in Germany","volume":"20","author":"Gensorowsky","year":"2022","journal-title":"Cost Eff. Resour. Alloc."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"104281","DOI":"10.1016\/j.ijmedinf.2020.104281","article-title":"Successfully implementing a national electronic health record: A rapid umbrella review","volume":"144","author":"Fennelly","year":"2020","journal-title":"Int. J. Med. Inform."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"104431","DOI":"10.1016\/j.ijmedinf.2021.104431","article-title":"Use of standardized terminologies in clinical practice: A scoping review","volume":"149","author":"Fennelly","year":"2021","journal-title":"Int. J. Med. Inform."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1038\/s41746-019-0158-1","article-title":"Why digital medicine depends on interoperability","volume":"2","author":"Lehne","year":"2019","journal-title":"NPJ Digit. Med."},{"key":"ref_63","doi-asserted-by":"crossref","unstructured":"Fennelly, O., Moroney, D., Doyle, D., Eustace-Cook, J., and Hughes, M. (Int. J. Med. Inform., 2023). Interoperability of Patient Portals with Electronic Health Records: A Scopring Review, Int. J. Med. Inform., under review.","DOI":"10.1016\/j.ijmedinf.2023.105335"}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/24\/12\/3780\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T14:56:45Z","timestamp":1760108205000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/24\/12\/3780"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,11]]},"references-count":63,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024,6]]}},"alternative-id":["s24123780"],"URL":"https:\/\/doi.org\/10.3390\/s24123780","relation":{},"ISSN":["1424-8220"],"issn-type":[{"value":"1424-8220","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,11]]}}}