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The ATP\u2013luciferin chemiluminescent solution was faced to a silicon photomultiplier (SiPM) for highly sensitive real-time detection. This system can detect ATP concentrations as low as 0.2 nM, with a sensitivity of 79.5 A\/M. Additionally, it offers rapid response times and can measure the characteristic time required for reactant diffusion and mixing within the reaction volume, determined to be 0.3 \u00b1 0.1 s. This corresponds to a diffusion velocity of approximately 44 \u00b1 14 mm2\/s.<\/jats:p>","DOI":"10.3390\/s24123921","type":"journal-article","created":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T11:14:16Z","timestamp":1718622856000},"page":"3921","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Miniaturizable Chemiluminescence System for ATP Detection in Water"],"prefix":"10.3390","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8430-8218","authenticated-orcid":false,"given":"Giuseppe E.","family":"Capuano","sequence":"first","affiliation":[{"name":"Istituto per la Microeletttronica e Microsistemi\u2014Consiglio Nazionale delle Ricerche, VIII Strada Z.I., 5, 95121 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"Corso","sequence":"additional","affiliation":[{"name":"Istituto per la Microeletttronica e Microsistemi\u2014Consiglio Nazionale delle Ricerche, VIII Strada Z.I., 5, 95121 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7884-8648","authenticated-orcid":false,"given":"Roberta","family":"Farina","sequence":"additional","affiliation":[{"name":"Istituto per la Microeletttronica e Microsistemi\u2014Consiglio Nazionale delle Ricerche, VIII Strada Z.I., 5, 95121 Catania, Italy"},{"name":"Department of Chemical Sciences, University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1843-0880","authenticated-orcid":false,"given":"Gianni","family":"Pezzotti Escobar","sequence":"additional","affiliation":[{"name":"URT \u201cLabSens of Beyond Nano\u201d of the Department of Physical Sciences and Technologies of Matter, National Research Council (CNR-DSFTM-ME), Viale Ferdinando Stagno D\u2019Alcontres 31, 98166 Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe A.","family":"Screpis","sequence":"additional","affiliation":[{"name":"Department of Medical, Surgical Sciences and Advanced Technologies, University of Catania, Via S. Sofia 78, 95123 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6119-0309","authenticated-orcid":false,"given":"Maria Anna","family":"Coniglio","sequence":"additional","affiliation":[{"name":"Istituto per la Microeletttronica e Microsistemi\u2014Consiglio Nazionale delle Ricerche, VIII Strada Z.I., 5, 95121 Catania, Italy"},{"name":"Department of Medical, Surgical Sciences and Advanced Technologies, University of Catania, Via S. Sofia 78, 95123 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8844-8568","authenticated-orcid":false,"given":"Sebania","family":"Libertino","sequence":"additional","affiliation":[{"name":"Istituto per la Microeletttronica e Microsistemi\u2014Consiglio Nazionale delle Ricerche, VIII Strada Z.I., 5, 95121 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,6,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1002\/bio.647","article-title":"Applications of biochemiluminescence to HACCP","volume":"16","author":"Champiat","year":"2001","journal-title":"Luminescence"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.tifs.2018.05.020","article-title":"Conventional and emerging detection techniques for pathogenic bacteria in food science: A review","volume":"81","author":"Hameed","year":"2018","journal-title":"Trends Food Sci. 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