{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T11:42:46Z","timestamp":1778931766627,"version":"3.51.4"},"reference-count":40,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2024,6,29]],"date-time":"2024-06-29T00:00:00Z","timestamp":1719619200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>In the realm of electrochemical nitrite detection, the potent oxidizing nature of nitrite typically necessitates operation at high detection potentials. However, this study introduces a novel approach to address this challenge by developing a highly sensitive electrochemical sensor with a low reduction detection potential. Specifically, a copper metal nanosheet\/carbon paper sensitive electrode (Cu\/CP) was fabricated using a one-step electrodeposition method, leveraging the catalytic reduction properties of copper\u2019s high occupancy d-orbital. The Cu\/CP sensor exhibited remarkable performance in nitrite detection, featuring a low detection potential of \u22120.05 V vs. Hg\/HgO, a wide linear range of 10~1000 \u03bcM, an impressive detection limit of 0.079 \u03bcM (S\/N = 3), and a high sensitivity of 2140 \u03bcA mM\u22121cm\u22122. These findings underscore the efficacy of electrochemical nitrite detection through catalytic reduction as a means to reduce the operational voltage of the sensor. By showcasing the successful implementation of this strategy, this work sets a valuable precedent for the advancement of electrochemical low-potential nitrite detection methodologies.<\/jats:p>","DOI":"10.3390\/s24134247","type":"journal-article","created":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T10:14:46Z","timestamp":1719828886000},"page":"4247","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["In Situ Preparation of Metallic Copper Nanosheets\/Carbon Paper Sensitive Electrodes for Low-Potential Electrochemical Detection of Nitrite"],"prefix":"10.3390","volume":"24","author":[{"given":"Xing","family":"Zhao","sequence":"first","affiliation":[{"name":"State Key Laboratory of Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun 130012, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guangfeng","family":"Zhou","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun 130012, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sitao","family":"Qin","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun 130012, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingwen","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun 130012, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guanda","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun 130012, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Gao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun 130012, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Suo","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun 130012, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun","family":"Zhao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun 130012, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,6,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Li, D., Wang, T., Li, Z., Xu, X., Wang, C., and Duan, Y. (2019). Application of graphene-based materials for detection of nitrate and nitrite in water\u2014A review. Sensors, 20.","DOI":"10.3390\/s20010054"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1007\/s11581-016-1666-5","article-title":"Single crystalline 3C-SiC whiskers used for electrochemical detection of nitrite under neutral condition","volume":"22","author":"Dong","year":"2016","journal-title":"Ionics"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"e202200823","DOI":"10.1002\/asia.202200823","article-title":"Gold nanomaterials and their composites as electrochemical sensing platforms for nitrite detection","volume":"17","author":"Saha","year":"2022","journal-title":"Chem.\u2013Asian J."},{"key":"ref_4","first-page":"1039","article-title":"Determination of trace nitrite by four wavelength negative absorption-catalytic spectrophotometry","volume":"32","author":"Zi","year":"2004","journal-title":"Chin. J. Anal. Chem."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.microc.2006.03.005","article-title":"Assay of femtogram level nitrite in human urine using luminol\u2013myoglobin chemiluminescence","volume":"84","author":"Yue","year":"2006","journal-title":"Microchem. J."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1093\/oxfordjournals.jbchem.a131769","article-title":"Purification to homogeneity of spinach nitrite reductase by ferredoxin-sepharose affinity chromatography","volume":"82","author":"IDA","year":"1977","journal-title":"J. Biochem."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1007\/s10967-009-0002-1","article-title":"Capillary electrophoresis determination of nitrate and nitrite in high-salt perchlorate solutions for the UC dissolution study","volume":"281","author":"Budanova","year":"2009","journal-title":"J. Radioanal. Nucl. Chem."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1007\/s11581-017-1972-6","article-title":"Electrochemical detection of aqueous nitrite based on poly (aniline-co-o-aminophenol)-modified glassy carbon electrode","volume":"23","author":"Liu","year":"2017","journal-title":"Ionics"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"130666","DOI":"10.1016\/j.foodchem.2021.130666","article-title":"Integrating electrochemical sensor based on MoO3\/Co3O4 heterostructure for highly sensitive sensing of nitrite in sausages and water","volume":"367","author":"Zhe","year":"2022","journal-title":"Food Chem."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1007\/s11581-022-04509-3","article-title":"Precious metal nanomaterial-modified electrochemical sensors for nitrite detection","volume":"28","author":"Zhang","year":"2022","journal-title":"Ionics"},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Hu, Y., He, F., Chen, C., Zhang, C., and Liu, J. (2022). Facile Controlled Synthesis of Pd-ZnO Nanostructures for Nitrite Detection. Molecules, 28.","DOI":"10.3390\/molecules28010099"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Xi, R., Zhang, S.H., Zhang, L., Wang, C., Wang, L.J., Yan, J.H., and Pan, G.B. (2019). Electrodeposition of Pd-Pt nanocomposites on porous GaN for electrochemical nitrite sensing. Sensors, 19.","DOI":"10.3390\/s19030606"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"109795","DOI":"10.1016\/j.microc.2023.109795","article-title":"Electrochemical surface functionalization engineering of carbon cloth for ultrasensitive electrochemical detection of nitrite","volume":"197","author":"Zhang","year":"2024","journal-title":"Microchem. J."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"127763","DOI":"10.1016\/j.matchemphys.2023.127763","article-title":"Simple and ultrasensitive self-supporting electrochemical sensor for nitrite based on cobalt oxide grafted carbon cloth","volume":"303","author":"Zhang","year":"2023","journal-title":"Mater. Chem. Phys."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"109302","DOI":"10.1016\/j.microc.2023.109302","article-title":"In situ fabrication of copper oxide nanoparticles decorated carbon cloth for efficient electrocatalytic detection of nitrite","volume":"194","author":"Zhang","year":"2023","journal-title":"Microchem. J."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.jelechem.2014.08.010","article-title":"Electroanalysis of nitrobenzene derivatives and nitrite ions using silver nanoparticles deposited silica spheres modified electrode","volume":"731","author":"Rameshkumar","year":"2014","journal-title":"J. Electroanal. Chem."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.synthmet.2011.12.013","article-title":"Constructions of polyaniline nanofiber-based electrochemical sensor for specific detection of nitrite and sensitive monitoring of ascorbic acid scavenging nitrite","volume":"162","author":"Wang","year":"2012","journal-title":"Synth. Met."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"7026","DOI":"10.1016\/j.tsf.2012.07.010","article-title":"Electrochemical detection of nitrite based on the polythionine\/carbon nanotube modified electrode","volume":"520","author":"Deng","year":"2012","journal-title":"Thin Solid Films"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"14731","DOI":"10.1021\/acs.iecr.2c02495","article-title":"Research progress on Cu-based catalysts for electrochemical nitrate reduction reaction to ammonia","volume":"61","author":"Teng","year":"2022","journal-title":"Ind. Eng. Chem. Res."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"225501","DOI":"10.1088\/1361-6528\/ac3da7","article-title":"Core\u2013shell Cu@ C@ ZIF-8 composite: A high-performance electrode material for electrochemical sensing of nitrite with high selectivity and sensitivity","volume":"33","author":"Gao","year":"2022","journal-title":"Nanotechnology"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"3635","DOI":"10.1039\/C5NJ02941D","article-title":"Au nanoparticle modified carbon paper electrode for an electrocatalytic oxidation nitrite sensor","volume":"40","author":"Wan","year":"2016","journal-title":"New J. Chem."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"339249","DOI":"10.1016\/j.aca.2021.339249","article-title":"Controlled synthesis of Cu-Sn alloy nanosheet arrays on carbon fiber paper for self-supported nonenzymatic glucose sensing","volume":"1190","author":"Li","year":"2022","journal-title":"Anal. Chim. Acta"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"128901","DOI":"10.1016\/j.foodchem.2020.128901","article-title":"A novel electrochemical paper sensor for low-cost detection of 5-methyltetrahydrofolate in egg yolk","volume":"346","author":"Yu","year":"2021","journal-title":"Food Chem."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"116721","DOI":"10.1016\/j.jelechem.2022.116721","article-title":"Enhanced ammonia sensitivity electrochemical sensors based on PtCu alloy nanoparticles in-situ synthesized on carbon cloth electrode","volume":"922","author":"Wang","year":"2022","journal-title":"J. Electroanal. Chem."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"127763","DOI":"10.1016\/j.snb.2020.127763","article-title":"Interfacial polymerized RGO\/MnFe2O4\/polyaniline fibrous nanocomposite supported glassy carbon electrode for selective and ultrasensitive detection of nitrite","volume":"309","author":"Sahoo","year":"2020","journal-title":"Sens. Actuators B Chem."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"124914","DOI":"10.1016\/j.jhazmat.2020.124914","article-title":"Pd\u2013Cu nanospheres supported on Mo2C for the electrochemical sensing of nitrites","volume":"408","author":"Vilian","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"106627","DOI":"10.1016\/j.microc.2021.106627","article-title":"Thermally reduced graphene\/nafion modified platinum disk electrode for trace level electrochemical detection of iron","volume":"169","author":"Nguyen","year":"2021","journal-title":"Microchem. J."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"131356","DOI":"10.1016\/j.foodchem.2021.131356","article-title":"Sensitive analytical detection of nitrite using an electrochemical sensor with STAB-functionalized Nb2C@ MWCNTs for signal amplification","volume":"372","author":"Chen","year":"2022","journal-title":"Food Chem."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"106904","DOI":"10.1016\/j.microc.2021.106904","article-title":"Synthesis and enhanced electrochemical properties of AuNPs@ MoS2\/rGO hybrid structures for highly sensitive nitrite detection","volume":"172","author":"Yang","year":"2022","journal-title":"Microchem. J."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"107777","DOI":"10.1016\/j.microc.2022.107777","article-title":"Facile synthesis of exfoliated graphite-supported cobalt ferrite (Co1.2Fe1.8O4) nanocomposite for the electrochemical detection of diclofenac","volume":"181","author":"Sundaresan","year":"2022","journal-title":"Microchem. J."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"130061","DOI":"10.1016\/j.snb.2021.130061","article-title":"Three-dimensional (3D) hierarchical structure engineering of AuNPs\/Co (OH) 2 nanocomposite on carbon cloth: An advanced and efficient electrode for highly sensitive and specific determination of nitrite","volume":"342","author":"Li","year":"2021","journal-title":"Sens. Actuators B Chem."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.snb.2019.02.017","article-title":"A novel electrochemical sensor based on GQDs-PANI\/ZnO-NCs modified glassy carbon electrode for simultaneous determination of Irinotecan and 5-Fluorouracil in biological samples","volume":"286","author":"Hatamluyi","year":"2019","journal-title":"Sens. Actuators B Chem."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"128221","DOI":"10.1016\/j.snb.2020.128221","article-title":"Cost-effective, wireless, and portable smartphone-based electrochemical system for on-site monitoring and spatial mapping of the nitrite contamination in water","volume":"319","author":"Xu","year":"2020","journal-title":"Sens. Actuators B Chem."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"110907","DOI":"10.1016\/j.diamond.2024.110907","article-title":"The electrochemical fabrication of Cu@ CeO2-rGO electrode for high-performance electrochemical nitrite sensor","volume":"143","author":"Temur","year":"2024","journal-title":"Diam. Relat. Mater."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"211255","DOI":"10.20964\/2021.12.53","article-title":"Preparation of reduced graphene oxide decorated with Cu-Co Oxide Electrode and its application for Sensitive Determination of Nitrite in Food Samples","volume":"16","author":"Ning","year":"2021","journal-title":"Int. J. Electrochem. Sci."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1016\/j.snb.2017.12.001","article-title":"Electrochemical detection of nitrite ions using Ag\/Cu\/MWNT nanoclusters electrodeposited on a glassy carbon electrode","volume":"258","author":"Zhang","year":"2018","journal-title":"Sens. Actuators B Chem."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"105439","DOI":"10.1016\/j.microc.2020.105439","article-title":"Rapid synthesis of cypress-like CuO nanomaterials and CuO\/MWCNTs composites for ultra-high sensitivity electrochemical sensing of nitrite","volume":"159","author":"Zhang","year":"2020","journal-title":"Microchem. J."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"111712","DOI":"10.1016\/j.materresbull.2021.111712","article-title":"Copper oxide nanoleaves covered with loose nickel oxide nanoparticles for sensitive and selective non-enzymatic nitrite sensors","volume":"149","author":"Li","year":"2022","journal-title":"Mater. Res. Bull."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.snb.2018.10.036","article-title":"Electrodeposition of gold nanoparticles on Cu-based metal-organic framework for the electrochemical detection of nitrite","volume":"286","author":"Chen","year":"2019","journal-title":"Sens. Actuators B Chem."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1002\/elan.201300082","article-title":"Pencil lead electrode modified with hemoglobin film as a novel biosensor for nitrite determination","volume":"25","author":"Majidi","year":"2013","journal-title":"Electroanalysis"}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/24\/13\/4247\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:08:02Z","timestamp":1760108882000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/24\/13\/4247"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,29]]},"references-count":40,"journal-issue":{"issue":"13","published-online":{"date-parts":[[2024,7]]}},"alternative-id":["s24134247"],"URL":"https:\/\/doi.org\/10.3390\/s24134247","relation":{},"ISSN":["1424-8220"],"issn-type":[{"value":"1424-8220","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,29]]}}}