{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T11:47:26Z","timestamp":1782906446598,"version":"3.54.5"},"reference-count":38,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2024,7,10]],"date-time":"2024-07-10T00:00:00Z","timestamp":1720569600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Chongqing University of Technology Research and Innovation Team Cultivation Program","award":["2023TDZ012"],"award-info":[{"award-number":["2023TDZ012"]}]},{"name":"Chongqing University of Technology Research and Innovation Team Cultivation Program","award":["2022Q535"],"award-info":[{"award-number":["2022Q535"]}]},{"name":"Chongqing University of Technology Research and Innovation Team Cultivation Program","award":["2023Q645"],"award-info":[{"award-number":["2023Q645"]}]},{"DOI":"10.13039\/501100004867","name":"Horizontal Project of Chongqing University of Technology","doi-asserted-by":"publisher","award":["2023TDZ012"],"award-info":[{"award-number":["2023TDZ012"]}],"id":[{"id":"10.13039\/501100004867","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004867","name":"Horizontal Project of Chongqing University of Technology","doi-asserted-by":"publisher","award":["2022Q535"],"award-info":[{"award-number":["2022Q535"]}],"id":[{"id":"10.13039\/501100004867","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004867","name":"Horizontal Project of Chongqing University of Technology","doi-asserted-by":"publisher","award":["2023Q645"],"award-info":[{"award-number":["2023Q645"]}],"id":[{"id":"10.13039\/501100004867","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Postdoctoral Research Station of Chongqing University Cancer Hospital","award":["2023TDZ012"],"award-info":[{"award-number":["2023TDZ012"]}]},{"name":"Postdoctoral Research Station of Chongqing University Cancer Hospital","award":["2022Q535"],"award-info":[{"award-number":["2022Q535"]}]},{"name":"Postdoctoral Research Station of Chongqing University Cancer Hospital","award":["2023Q645"],"award-info":[{"award-number":["2023Q645"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Surface-enhanced Raman spectroscopy (SERS) is a promising and highly sensitive molecular fingerprint detection technology. However, the development of SERS nanocomposites that are label-free, highly sensitive, selective, stable, and reusable for gaseous volatile organic compounds (VOCs) detection remains a challenge. Here, we report a novel TiO2NTs\/AuNPs@ZIF\u22128 nanocomposite for the ultrasensitive SERS detection of VOCs. The three-dimensional TiO2 nanotube structure with a large specific surface area provides abundant sites for the loading of Au NPs, which possess excellent local surface plasmon resonance (LSPR) effects, further leading to the formation of a large number of SERS active hotspots. The externally wrapped porous MOF structure adsorbs more gaseous VOC molecules onto the noble metal surface. Under the synergistic mechanism of physical and chemical enhancement, a better SERS enhancement effect can be achieved. By optimizing experimental conditions, the SERS detection limit for acetophenone, a common exhaled VOC, is as low as 10\u221211 M. And the relative standard deviation of SERS signal intensity from different points on the same nanocomposite surface is 4.7%. The acetophenone gas achieves a 1 min response and the signal reaches stability in 4 min. Under UV irradiation, the surface-adsorbed acetophenone can be completely degraded within 40 min. The experimental results demonstrate that this nanocomposite has good detection sensitivity, repeatability, selectivity, response speed, and reusability, making it a promising sensor for gaseous VOCs.<\/jats:p>","DOI":"10.3390\/s24144447","type":"journal-article","created":{"date-parts":[[2024,7,10]],"date-time":"2024-07-10T11:14:41Z","timestamp":1720610081000},"page":"4447","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Facile Preparation of TiO2NTs\/Au@MOF Nanocomposites for High-Sensitivity SERS Sensing of Gaseous VOC"],"prefix":"10.3390","volume":"24","author":[{"given":"Chunyan","family":"Wang","sequence":"first","affiliation":[{"name":"Chongqing University Cancer Hospital, Chongqing 400044, China"},{"name":"College of Pharmacy and Bioengineering, Chongqing University of Technology, Chongqing 400054, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yina","family":"Jiang","sequence":"additional","affiliation":[{"name":"College of Pharmacy and Bioengineering, Chongqing University of Technology, Chongqing 400054, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuyu","family":"Peng","sequence":"additional","affiliation":[{"name":"College of Pharmacy and Bioengineering, Chongqing University of Technology, Chongqing 400054, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Huo","sequence":"additional","affiliation":[{"name":"Chongqing DeWen ZhiShang Education Technology Co., Ltd., Chongqing 400042, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ban","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Economics, Mongolian University of Life Sciences, Ulaanbaatar 17024, Mongolia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,7,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/s41664-021-00194-9","article-title":"Mass spectrometry-based human breath analysis: Towards COVID-19 diagnosis and research","volume":"5","author":"Yuan","year":"2021","journal-title":"J. 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