{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T22:10:54Z","timestamp":1775599854633,"version":"3.50.1"},"reference-count":43,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2024,7,20]],"date-time":"2024-07-20T00:00:00Z","timestamp":1721433600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Science and Technology Development Funds of Shaanxi Province","award":["2024QCY-KXJ-179"],"award-info":[{"award-number":["2024QCY-KXJ-179"]}]},{"name":"Science and Technology Development Funds of Shaanxi Province","award":["2021JM-204"],"award-info":[{"award-number":["2021JM-204"]}]},{"name":"Science and Technology Development Funds of Shaanxi Province","award":["2022JQ-612"],"award-info":[{"award-number":["2022JQ-612"]}]},{"DOI":"10.13039\/501100007128","name":"Natural Science Foundation of Shaanxi Province","doi-asserted-by":"publisher","award":["2024QCY-KXJ-179"],"award-info":[{"award-number":["2024QCY-KXJ-179"]}],"id":[{"id":"10.13039\/501100007128","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007128","name":"Natural Science Foundation of Shaanxi Province","doi-asserted-by":"publisher","award":["2021JM-204"],"award-info":[{"award-number":["2021JM-204"]}],"id":[{"id":"10.13039\/501100007128","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007128","name":"Natural Science Foundation of Shaanxi Province","doi-asserted-by":"publisher","award":["2022JQ-612"],"award-info":[{"award-number":["2022JQ-612"]}],"id":[{"id":"10.13039\/501100007128","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>This paper proposes a full-automatic high-efficiency Mueller matrix microscopic imaging (MMMI) system based on the tissue microarray (TMA) for cancer inspection for the first time. By performing a polar decomposition on the sample\u2019s Mueller matrix (MM) obtained by a transmissive MMMI system we established, the linear phase retardance equivalent waveplate fast-axis azimuth and the linear phase retardance are obtained for distinguishing the cancerous tissues from the normal ones based on the differences in their polarization characteristics, where three analyses methods including statistical analysis, the gray-level co-occurrence matrix analysis (GLCM) and the Tamura image processing method (TIPM) are used. Previous MMMI medical diagnostics typically utilized discrete slices for inspection under a high-magnification objective (20\u00d7\u201350\u00d7) with a small field of view, while we use the TMA under a low-magnification objective (5\u00d7) with a large field of view. Experimental results indicate that MMMI based on TMA can effectively analyze the pathological variations in biological tissues, inspect cancerous cervical tissues, and thus contribute to the diagnosis of postoperative cancer biopsies. Such an inspection method, using a large number of samples within a TMA, is beneficial for obtaining consistent findings and good reproducibility.<\/jats:p>","DOI":"10.3390\/s24144703","type":"journal-article","created":{"date-parts":[[2024,7,22]],"date-time":"2024-07-22T14:45:53Z","timestamp":1721659553000},"page":"4703","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Full-Automatic High-Efficiency Mueller Matrix Microscopy Imaging for Tissue Microarray Inspection"],"prefix":"10.3390","volume":"24","author":[{"given":"Hanyue","family":"Wei","sequence":"first","affiliation":[{"name":"School of Physics and Information Technology, Shaanxi Normal University, Xi\u2019an 710119, China"},{"name":"Xi\u2019an Key Laboratory of Optical Information Manipulation and Augmentation (OMA), Xi\u2019an 710119, China"}]},{"given":"Yifu","family":"Zhou","sequence":"additional","affiliation":[{"name":"School of Physics and Information Technology, Shaanxi Normal University, Xi\u2019an 710119, China"},{"name":"Xi\u2019an Key Laboratory of Optical Information Manipulation and Augmentation (OMA), Xi\u2019an 710119, China"}]},{"given":"Feiya","family":"Ma","sequence":"additional","affiliation":[{"name":"School of Physics and Information Technology, Shaanxi Normal University, Xi\u2019an 710119, China"},{"name":"Xi\u2019an Key Laboratory of Optical Information Manipulation and Augmentation (OMA), Xi\u2019an 710119, China"}]},{"given":"Rui","family":"Yang","sequence":"additional","affiliation":[{"name":"School of Physics and Information Technology, Shaanxi Normal University, Xi\u2019an 710119, China"},{"name":"Xi\u2019an Key Laboratory of Optical Information Manipulation and Augmentation (OMA), Xi\u2019an 710119, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0324-1497","authenticated-orcid":false,"given":"Jian","family":"Liang","sequence":"additional","affiliation":[{"name":"School of Physics and Information Technology, Shaanxi Normal University, Xi\u2019an 710119, China"},{"name":"Xi\u2019an Key Laboratory of Optical Information Manipulation and Augmentation (OMA), Xi\u2019an 710119, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7547-7511","authenticated-orcid":false,"given":"Liyong","family":"Ren","sequence":"additional","affiliation":[{"name":"School of Physics and Information Technology, Shaanxi Normal University, Xi\u2019an 710119, China"},{"name":"Xi\u2019an Key Laboratory of Optical Information Manipulation and Augmentation (OMA), Xi\u2019an 710119, China"},{"name":"Robust (Xixian New Area) Opto-Electro Technologies Co., Ltd., Xi\u2019an 712000, China"}]}],"member":"1968","published-online":{"date-parts":[[2024,7,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Rahaman, A., Anantharaju, A., Jeyachandran, K., Manideep, R., and Pal, U.M. 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