{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T06:58:39Z","timestamp":1777618719803,"version":"3.51.4"},"reference-count":35,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2024,7,27]],"date-time":"2024-07-27T00:00:00Z","timestamp":1722038400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"NIHR Leicester BRC"},{"name":"NIHR Applied Research Collaboration (ARC) East Midlands"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Diabetic Foot Ulcers (DFUs) are a major complication of diabetes, with treatment requiring offloading. This study aimed to capture how the accelerometer-assessed physical activity profile differs in those with DFUs compared to those with diabetes but without ulceration (non-DFU). Participants were requested to wear an accelerometer on their non-dominant wrist for up to 8days. Physical activity outcomes included average acceleration (volume), intensity gradient (intensity distribution), the intensity of the most active sustained (continuous) 5\u2013120 min of activity (MXCONT), and accumulated 5\u2013120 min of activity (MXACC). A total of 595 participants (non-DFU = 561, DFU = 34) were included in the analysis. Average acceleration was lower in DFU participants compared to non-DFU participants (21.9 mg [95%CI:21.2, 22.7] vs. 16.9 mg [15.3, 18.8], p &lt; 0.001). DFU participants also had a lower intensity gradient, indicating proportionally less time spent in higher-intensity activities. The relative difference between DFU and non-DFU participants was greater for sustained activity (MXCONT) than for accumulated (MXACC) activity. In conclusion, physical activity, particularly the intensity of sustained activity, is lower in those with DFUs compared to non-DFUs. This highlights the need for safe, offloaded modes of activity that contribute to an active lifestyle for people with DFUs.<\/jats:p>","DOI":"10.3390\/s24154875","type":"journal-article","created":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T12:27:43Z","timestamp":1722256063000},"page":"4875","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Capturing How the Accelerometer Measured Physical Activity Profile Differs in People with Diabetic Foot Ulceration"],"prefix":"10.3390","volume":"24","author":[{"given":"Liam","family":"Neal","sequence":"first","affiliation":[{"name":"Diabetes Research Centre, University Hospitals of Leicester NHS Trust, Leicester LE5 4PW, UK"},{"name":"NIHR Applied Research Collaboration East Midlands (ARC EM), University of Leicester, Leicester LE1 7RH, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"McCarthy","sequence":"additional","affiliation":[{"name":"Diabetes Research Centre, University Hospitals of Leicester NHS Trust, Leicester LE5 4PW, UK"},{"name":"NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester LE5 4PW, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1714-6087","authenticated-orcid":false,"given":"Paddy","family":"Dempsey","sequence":"additional","affiliation":[{"name":"Diabetes Research Centre, University Hospitals of Leicester NHS Trust, Leicester LE5 4PW, UK"},{"name":"School of Exercise & Nutrition Sciences, Deakin University, Burwood 3125, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Zaccardi","sequence":"additional","affiliation":[{"name":"Diabetes Research Centre, University Hospitals of Leicester NHS Trust, Leicester LE5 4PW, 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