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The advent of portable and wearable acoustic sensing devices marks a significant milestone in telemedicine, home health, and clinical diagnostics. This review summarises the contemporary advancements in acoustic sensing devices, categorized based on varied sensing principles, including capacitive, piezoelectric, and triboelectric mechanisms. Some representative acoustic sensing devices are introduced from the perspective of portability and wearability. Additionally, the characteristics of sound signals from different human organs and practical applications of acoustic sensing devices are exemplified. Challenges and prospective trends in portable and wearable acoustic sensors are also discussed, providing insights into future research directions.<\/jats:p>","DOI":"10.3390\/s24165354","type":"journal-article","created":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T01:38:45Z","timestamp":1724117925000},"page":"5354","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Advances in Portable and Wearable Acoustic Sensing Devices for Human Health Monitoring"],"prefix":"10.3390","volume":"24","author":[{"given":"Fanhao","family":"Kong","sequence":"first","affiliation":[{"name":"School of Medical Technology, Beijing Institute of Technology, Beijing 100081, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2557-4230","authenticated-orcid":false,"given":"Yang","family":"Zou","sequence":"additional","affiliation":[{"name":"School of Medical Technology, Beijing Institute of Technology, Beijing 100081, China"},{"name":"Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing 101400, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9952-7296","authenticated-orcid":false,"given":"Zhou","family":"Li","sequence":"additional","affiliation":[{"name":"Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing 101400, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0720-4052","authenticated-orcid":false,"given":"Yulin","family":"Deng","sequence":"additional","affiliation":[{"name":"School of Medical Technology, Beijing Institute of Technology, Beijing 100081, China"}]}],"member":"1968","published-online":{"date-parts":[[2024,8,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2209673","DOI":"10.1002\/adma.202209673","article-title":"Emerging Trends in Soft Electronics: Integrating Machine Intelligence with Soft Acoustic\/Vibration Sensors","volume":"35","author":"Lee","year":"2023","journal-title":"Adv. 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