{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:21:15Z","timestamp":1760145675896,"version":"build-2065373602"},"reference-count":42,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2024,8,21]],"date-time":"2024-08-21T00:00:00Z","timestamp":1724198400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["61902287"],"award-info":[{"award-number":["61902287"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Tremor is a prevalent neurological disorder characterized by involuntary shaking or trembling of body parts. This condition impairs fine motor skills and hand coordination to varying degrees and can even affect overall body mobility. As a result, tremors severely disrupt the daily lives and work of those affected, significantly limiting their physical activity space. This study developed an innovative spatial augmented reality (SAR) system aimed at assisting individuals with tremor disorders to overcome their physical limitations and expand their range of activities. The system integrates eye-tracking and Internet of Things (IoT) technologies, enabling users to smoothly control objects in the real world through eye movements. It uses a virtual stabilization algorithm for stable interaction with objects in the real environment. The study comprehensively evaluated the system\u2019s performance through three experiments: (1) assessing the effectiveness of the virtual stabilization algorithm in enhancing the system\u2019s ability to assist individuals with tremors in stable and efficient interaction with remote objects, (2) evaluating the system\u2019s fluidity and stability in performing complex interactive tasks, and (3) investigating the precision and efficiency of the system in remote interactions within complex physical environments. The results demonstrated that the system significantly improves the stability and efficiency of interactions between individuals with tremor and remote objects, reduces operational errors, and enhances the accuracy and communication efficiency of interactions.<\/jats:p>","DOI":"10.3390\/s24165405","type":"journal-article","created":{"date-parts":[[2024,8,23]],"date-time":"2024-08-23T12:58:07Z","timestamp":1724417887000},"page":"5405","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Spatial Augmented Reality for Expanding the Reach of Individuals with Tremor beyond Their Physical Limits"],"prefix":"10.3390","volume":"24","author":[{"given":"Kai","family":"Wang","sequence":"first","affiliation":[{"name":"School of Art and Design, Wuhan University of Technology, Wuhan 430070, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengjing","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Art and Design, Wuhan University of Technology, Wuhan 430070, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi","family":"Sun","sequence":"additional","affiliation":[{"name":"School of Art and Design, Wuhan University of Technology, Wuhan 430070, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qun","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Art and Design, Wuhan University of Technology, Wuhan 430070, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,8,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/s40673-020-00121-1","article-title":"Essential tremor: The most common form of cerebellar degeneration","volume":"7","author":"Louis","year":"2020","journal-title":"Cerebellum Ataxias"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Lenka, A., and Jankovic, J. (2021). Tremor syndromes: An updated review. Front. Neurol., 12.","DOI":"10.3389\/fneur.2021.684835"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"S369","DOI":"10.1016\/S1353-8020(08)70032-4","article-title":"Parkinsonism & related disorders. Tremor","volume":"13","author":"Bain","year":"2007","journal-title":"Park. Relat. Disord."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"28","DOI":"10.5334\/tohm.632","article-title":"How common is essential tremor? Update on the worldwide prevalence of essential tremor","volume":"11","author":"Louis","year":"2021","journal-title":"Tremor Other Hyperkinetic Mov."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/s41572-021-00314-w","article-title":"Essential tremor","volume":"7","author":"Welton","year":"2021","journal-title":"Nat. Rev. Dis. Primers"},{"key":"ref_6","unstructured":"National Institute of Neurological Disordersand Stroke (2023, December 10). Tremor, Available online: https:\/\/www.ninds.nih.gov\/health-information\/disorders\/tremor."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Louis, E.D. (2012). Treatment of essential tremor: Are there issues we are overlooking. Front. Neurol., 2.","DOI":"10.3389\/fneur.2011.00091"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1212\/WNL.0b013e318236f0fd","article-title":"Evidence-based guideline update: Treatment of essential tremor: Report of the Quality Standards subcommittee of the American Academy of Neurology","volume":"77","author":"Zesiewicz","year":"2011","journal-title":"Neurology"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1136\/jnnp-2018-318240","article-title":"Outcomes from stereotactic surgery for essential tremor","volume":"90","author":"Dallapiazza","year":"2019","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Mo, J., and Priefer, R. (2021). Medical devices for tremor suppression: Current status and future directions. Biosensors, 11.","DOI":"10.3390\/bios11040099"},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Nguyen, H.S., and Luu, T.P. (2021). Tremor-suppression orthoses for the upper limb: Current developments and future challenges. Front. Human. Neurosci., 15.","DOI":"10.3389\/fnhum.2021.622535"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Bimber, O., and Raskar, R. (2005). Spatial Augmented Reality: Merging Real and Virtual Worlds, CRC Press.","DOI":"10.1201\/b10624"},{"key":"ref_13","first-page":"17","article-title":"Attenuation of wrist tremor with closed-loop electrical stimulation of muscles","volume":"414","author":"Elek","year":"1989","journal-title":"J. Physiol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/BF02368521","article-title":"Attenuation of pathological tremors by functional electrical stimulation I: Method","volume":"20","author":"Prochazka","year":"1992","journal-title":"Ann. Biomed. Eng."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/BF02368522","article-title":"Attenuation of pathological tremors by functional electrical stimulation II: Clinical evaluation","volume":"20","author":"Javidan","year":"1992","journal-title":"Ann. Biomed. Eng."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Dideriksen, J.L., Laine, C.M., Dosen, S., Muceli, S., Rocon, E., Pons, J.L., Benito-Leon, J., and Farina, D. (2017). Electrical Stimulation of Afferent Pathways for the Suppression of Pathological Tremor. Front. Neurosci., 11.","DOI":"10.3389\/fnins.2017.00178"},{"key":"ref_17","unstructured":"Elias, M., Patel, S., Maamary, E., Araneta, L., and Obaid, N. (2019). Apparatus for Damping Involuntary Hand Motions. (US20190216628A1), U.S. Patent."},{"key":"ref_18","unstructured":"Hunter, R., Pivach, L., Madere, K., and Van Gemmert, A.W. (2018, January 9). Potential benefits of the Readi-Steadi on essential tremor. Proceedings of the 5th Annual LSU Discover Day, Baton Rouge, LA, USA."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1186\/s12984-019-0543-7","article-title":"Need for mechanically and ergonomically enhanced tremor-suppression orthoses for the upper limb: A systematic review","volume":"16","author":"Fromme","year":"2019","journal-title":"Neuroeng. Rehabil."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1089\/soro.2019.0194","article-title":"Soft Exoskeleton for Tremor Suppression Equipped with Flexible Semiactive Actuator","volume":"8","author":"Zahedi","year":"2020","journal-title":"Soft Robot."},{"key":"ref_21","unstructured":"Rocon, E., Ruiz, A.F., Pons, J.L., Belda-Lois, J.M., and S\u00e1nchez-Lacuesta, J.J. (2005, January 18\u201322). A Wearable Exo-Skeleton for Tremor Assessment and Suppression. Proceedings of the 2005 IEEE International Conference on Robotics and Automation, Barcelona, Spain."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1109\/TNSRE.2007.903917","article-title":"Design and Validation of a Rehabilitation Robotic Exoskeleton for Tremor Assessment and Suppression","volume":"15","author":"Rocon","year":"2007","journal-title":"IEEE Trans. Neural Syst. Rehabil. Eng."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1109\/TMECH.2014.2317948","article-title":"Adaptive Suppression of Severe Pathological Tremor by Torque Estimation Method","volume":"20","author":"Taheri","year":"2014","journal-title":"IEEE\/ASME Trans. Mechatron."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1007\/s42600-023-00323-6","article-title":"Tremor stabilization improvement using anti-tremor band: A machine learning\u2013based technique","volume":"39","author":"Biswas","year":"2023","journal-title":"Res. Biomed. Eng."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"2757","DOI":"10.1007\/s11517-023-02886-z","article-title":"FiMec tremor stabilization spoon: Design and active stabilization control of two DoF robotic eating devices for hand tremor patients","volume":"61","author":"Tatar","year":"2023","journal-title":"Med. Biol. Eng. Comput."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"409","DOI":"10.4103\/aian.AIAN_251_19","article-title":"Shaken not stirred: A pilot study testing a gyroscopic spoon stabilization device in Parkinson\u2019s disease and tremor","volume":"23","author":"Ryden","year":"2020","journal-title":"Ann. Indian. Acad. Neurol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1147\/sj.443.0621","article-title":"A mouse adapter for people with hand tremor","volume":"44","author":"Levine","year":"2005","journal-title":"IBM Syst. J."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1145\/3161169","article-title":"Improving input accuracy on smartphones for persons who are affected by tremor using motion sensors","volume":"1","author":"Plaumann","year":"2018","journal-title":"Proc. ACM Interact. Mob. Wearable Ubiquitous Technol."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Wacharamanotham, C., Hurtmanns, J., Mertens, A., Kronenbuerger, M., Schlick, C., and Borchers, J. (2011, January 7). Evaluating swabbing: A touchscreen input method for elderly users with tremor. Proceedings of the SIGCHI Conference on Human Factors in Computing Systems, Vancouver, BC, Canada.","DOI":"10.1145\/1978942.1979031"},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Wang, K., Tan, D., Li, Z., and Sun, Z. (2023). Supporting Tremor Rehabilitation Using Optical See-Through Augmented Reality Technology. Sensors, 23.","DOI":"10.3390\/s23083924"},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Chen, Y., Inaltekin, H., and Gorlatova, M. (2023, January 17\u201320). Adapt SLAM: Edge-assisted adaptive SLAM with resource constraints via uncertainty minimization. Proceedings of the IEEE INFOCOM 2023-IEEE Conference on Computer Communications, New York, NY, USA.","DOI":"10.1109\/INFOCOM53939.2023.10229009"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"17812","DOI":"10.1109\/JIOT.2024.3360414","article-title":"Digital Twin-Based 3D Map Management for Edge-Assisted Device Pose Tracking in Mobile AR","volume":"11","author":"Zhou","year":"2024","journal-title":"IEEE Internet Things J."},{"key":"ref_33","first-page":"227","article-title":"A typing assist system considering involuntary hand tremor","volume":"21","author":"Wang","year":"2016","journal-title":"Trans. Virtual Real. Soc. Jpn."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"10700","DOI":"10.1109\/ACCESS.2017.2711058","article-title":"Supporting trembling hand typing using optical see-through mixed reality","volume":"5","author":"Wang","year":"2017","journal-title":"IEEE Access"},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Ueda, Y., Asai, Y., Enomoto, R., Wang, K., Iwai, D., and Sato, K. (2017, January 16). Body cyberization by spatial augmented reality for reaching unreachable world. Proceedings of the 8th Augmented Human International Conference, Mountain View, CA, USA.","DOI":"10.1145\/3041164.3041188"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"5739301","DOI":"10.1155\/2017\/5739301","article-title":"Eye Tracking Based Control System for Natural Human-Computer Interaction","volume":"2017","author":"Zhang","year":"2017","journal-title":"Comput. Intell. Neurosci."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1136\/jnnp.2010.212407","article-title":"Eye movements in amyotrophic lateral sclerosis and its mimics: A review with illustrative cases","volume":"82","author":"Donaghy","year":"2011","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_38","unstructured":"De Gaudenzi, E., and Porta, M. (2013, January 7\u20139). Towards effective eye pointing for gaze-enhanced human-computer interaction. Proceedings of the 2013 Science and Information Conference, London, UK."},{"key":"ref_39","first-page":"1118","article-title":"Design an eye tracking mouse","volume":"2","author":"Nehete","year":"2013","journal-title":"Int. J. Adv. Res. Comput. Commun. Eng."},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Missimer, E., and Betke, M. (2010, January 23\u201325). Blink and wink detection for mouse pointer control. Proceedings of the 3rd International Conference on PErvasive Technologies Related to Assistive Environments, Samos, Greece.","DOI":"10.1145\/1839294.1839322"},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Shahid, E., Ur Rehman, M.Z., Sheraz, M., Khan, W., and Aqib, M. (2019, January 24\u201325). Eye Monitored Wheelchair ControlIn Proceedings of the 2019 International Conference on Electrical, Communication, and Computer Engineering (ICECCE 2019). Swat, Pakistan.","DOI":"10.1109\/ICECCE47252.2019.8940642"},{"key":"ref_42","first-page":"16","article-title":"Analysis of the electrophysiological features of tremor and essential tremor in Parkinson\u2019s disease","volume":"21","author":"Xu","year":"2017","journal-title":"Chin. J. Pract. Nerv. Dis."}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/24\/16\/5405\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:40:29Z","timestamp":1760110829000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/24\/16\/5405"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,21]]},"references-count":42,"journal-issue":{"issue":"16","published-online":{"date-parts":[[2024,8]]}},"alternative-id":["s24165405"],"URL":"https:\/\/doi.org\/10.3390\/s24165405","relation":{},"ISSN":["1424-8220"],"issn-type":[{"type":"electronic","value":"1424-8220"}],"subject":[],"published":{"date-parts":[[2024,8,21]]}}}