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Among the candidates of conductive fillers, conductive polymers have become popular due to their intrinsic conductivity, high biocompatibility, and mechanical flexibility. However, it is still a challenge to construct conductive polymer-incorporated hydrogels with a good performance using a facile method. Herein, we present a simple method for the one-pot preparation of conductive polymer-incorporated hydrogels involving rapid photocuring of the hydrogel template followed by slow in situ polymerization of pyrrole. Due to the use of a milder oxidant, hydrogen peroxide, for polypyrrole synthesis, the photocuring of the hydrogel template and the growing of polypyrrole proceeded in an orderly manner, making it possible to prepare conductive polymer-incorporated hydrogels in one pot. The preparation process is facile and extensible. Moreover, the obtained hydrogels exhibit a series of properties suitable for biomedical strain sensors, including good conductivity (2.49 mS\/cm), high stretchability (&gt;200%), and a low Young\u2019s modulus (~30 kPa) that is compatible with human skin.<\/jats:p>","DOI":"10.3390\/s24175814","type":"journal-article","created":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T05:06:06Z","timestamp":1725858366000},"page":"5814","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Facile One-Pot Preparation of Polypyrrole-Incorporated Conductive Hydrogels for Human Motion Sensing"],"prefix":"10.3390","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-4772-2676","authenticated-orcid":false,"given":"Zunhui","family":"Zhao","sequence":"first","affiliation":[{"name":"Liaoning Key Lab of Integrated Circuit and Biomedical Electronic System, School of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian 116024, China"}]},{"given":"Jiahao","family":"Liu","sequence":"additional","affiliation":[{"name":"Liaoning Key Lab of Integrated Circuit and Biomedical Electronic System, School of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian 116024, China"}]},{"given":"Jun","family":"Lv","sequence":"additional","affiliation":[{"name":"School of Mechanics and Aerospace Engineering, Dalian University of Technology, Dalian 116024, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5375-0505","authenticated-orcid":false,"given":"Bo","family":"Liu","sequence":"additional","affiliation":[{"name":"Liaoning Key Lab of Integrated Circuit and Biomedical Electronic System, School of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian 116024, China"}]},{"given":"Na","family":"Li","sequence":"additional","affiliation":[{"name":"Liaoning Key Lab of Integrated Circuit and Biomedical Electronic System, School of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian 116024, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5392-8019","authenticated-orcid":false,"given":"Hangyu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Liaoning Key Lab of Integrated Circuit and Biomedical Electronic System, School of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian 116024, China"}]}],"member":"1968","published-online":{"date-parts":[[2024,9,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1021\/acsmaterialslett.0c00309","article-title":"Functional Conductive Hydrogels for Bioelectronics","volume":"2","author":"Fu","year":"2020","journal-title":"ACS Mater. 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