{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T02:50:52Z","timestamp":1760237452604,"version":"build-2065373602"},"reference-count":35,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2020,5,20]],"date-time":"2020-05-20T00:00:00Z","timestamp":1589932800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Symmetry"],"abstract":"<jats:p>Surface Plasma resonance (SPR) sensors combined with biological receptors are widely used in biosensors. Due to limitations of measurement techniques, small-scale, low accuracy, and sensitivity to the refractive index of solution in traditional SPR prism sensor arise. As a consequence, it is difficult to launch commercial production of SPR sensors. The theory of localized surface plasmon resonance (LSPR) developed based on SPR theory has stronger coupling ability to near-field photons. Based on the LSPR sensing theory, we propose a submicron-sized golden-disk and graphene composite structure. By varying the thickness and diameter of the array disk, the performance of the LSPR sensor can be optimized. A graphene layer sandwiched between the golden-disk and the silver film can prevent the latter from oxidizing. Symmetrical design enables high-low concentration of dual-channel distributed sensing. As the fixed light source, we use a 632.8-nm laser. A golden nano-disk with 45 nm thickness and 70 nm radius is designed, using a finite difference time domain (FDTD) simulation system. When the incident angle is 42\u00b0, the figure of merit (FOM) reaches 8826, and the measurable refractive index range reaches 0.2317.<\/jats:p>","DOI":"10.3390\/sym12050841","type":"journal-article","created":{"date-parts":[[2020,5,20]],"date-time":"2020-05-20T10:37:38Z","timestamp":1589971058000},"page":"841","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Design and Optimization of Plasmon Resonance Sensor Based on Micro\u2013Nano Symmetrical Localized Surface"],"prefix":"10.3390","volume":"12","author":[{"given":"Fengyu","family":"Yin","sequence":"first","affiliation":[{"name":"School of Electronic and Electrical Engineering, Shanghai University of Engineering Science, Shanghai 201620, China"}]},{"given":"Jin","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Electronic and Electrical Engineering, Shanghai University of Engineering Science, Shanghai 201620, China"}]},{"given":"Haima","family":"Yang","sequence":"additional","affiliation":[{"name":"School of Optical-Electrical and Computer Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7211-0741","authenticated-orcid":false,"given":"Aleksey","family":"Kudreyko","sequence":"additional","affiliation":[{"name":"Department of Medical Physics and Informatics, Bashkir State Medical University, Lenina st. 3, 450008 Ufa, Russia"}]},{"given":"Bo","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Electronic and Electrical Engineering, Shanghai University of Engineering Science, Shanghai 201620, China"}]}],"member":"1968","published-online":{"date-parts":[[2020,5,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"32","DOI":"10.2144\/000113569","article-title":"Label-free analysis of biomolecular interactions using SPR imagin","volume":"50","author":"Kodoyianni","year":"2011","journal-title":"Biotechniques"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1063\/1.95819","article-title":"Enhanced quantum efficiency internal photoemission detectors by grating coupling to surface plasma waves","volume":"46","author":"Brueck","year":"1985","journal-title":"Appl. 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