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E-Health is defined as \u201cthe ability to seek, find, understand and appraise health information derived from electronic sources and acquired knowledge to properly solve or treat health problems. As a repository for health information as well as e-Health analysis, the Internet has the potential to protect consumers from harm and empower them to participate fully in informed health-related decision-making. Most importantly, high levels of e-Health integration mitigate the risk of encountering unreliable information on the Internet. Various research perspectives related to security and privacy within IoT-cloud-based e-Health systems are examined, with an emphasis on the opportunities, benefits and challenges of the implementation such systems. The combination of IoT-based e-Health systems integrated with intelligent systems such as cloud computing that provide smart objectives and applications is a promising future trend.<\/jats:p>","DOI":"10.3390\/sym12071191","type":"journal-article","created":{"date-parts":[[2020,7,22]],"date-time":"2020-07-22T05:10:30Z","timestamp":1595394630000},"page":"1191","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":185,"title":["Security and Privacy in IoT-Cloud-Based e-Health Systems\u2014A Comprehensive Review"],"prefix":"10.3390","volume":"12","author":[{"given":"Chanapha","family":"Butpheng","sequence":"first","affiliation":[{"name":"Department of Information Management, National Dong Hwa University, Hualien 97401, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0598-761X","authenticated-orcid":false,"given":"Kuo-Hui","family":"Yeh","sequence":"additional","affiliation":[{"name":"Department of Information Management, National Dong Hwa University, Hualien 97401, Taiwan"},{"name":"Department of Computer Science and Engineering, National Sun Yat-sen University, Kaohsiung 804, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hu","family":"Xiong","sequence":"additional","affiliation":[{"name":"School of Information and Software Engineering, University of Electronic Science and Technology of China, Chengdu 610054, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,7,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e20","DOI":"10.2196\/jmir.3.2.e20","article-title":"What is e-health?","volume":"3","author":"Eysenbach","year":"2001","journal-title":"J. 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