{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T22:19:32Z","timestamp":1778883572736,"version":"3.51.4"},"reference-count":33,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2021,5,11]],"date-time":"2021-05-11T00:00:00Z","timestamp":1620691200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Symmetry"],"abstract":"<jats:p>This experimental study defines the usage of a computer-aided surgical simulation process that is effective, safe, user-friendly, and low-cost, that achieves a detailed and realistic representation of the anatomical region of interest. The chosen tools for this purpose are state-of-the-art Computer Aided Design (CAD) software for mechanical design, and are the fundamental application dedicated to parametric modeling. These tools support different work environments, each one is for a specific type of modeling, and they allow the simulation of surgery. The result will be a faithful representation of the anatomical part both before and after the surgical procedure, screening all the intermediate phases. The doctor will assess different lines of action according to the results, then he will communicate them to the engineer who, consequently, will correct the antisymmetric issue and regenerate the model. Exact measurements of the mutual positions of the various components, skeletal and synthetic, can be achieved; all the osteosynthesis tools, necessary for the surgeon, can be included in the project according to different types of fracture to perfectly match the morphology of the bone to be treated. The method has been tested on seven clinical cases of different complexity and nature and the results of the simulations have been found to be of great effectiveness in the phase of diagnosis and of preoperative planning for the doctors and surgeons; therefore, allowing a lower risk medical operation with a better outcome. This work delivers experimental results in line with theoretical research findings in detail; moreover, full experimental and\/or methodical details are provided, so that outcomes could be obtained.<\/jats:p>","DOI":"10.3390\/sym13050850","type":"journal-article","created":{"date-parts":[[2021,5,11]],"date-time":"2021-05-11T22:53:40Z","timestamp":1620773620000},"page":"850","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effectiveness Assessment of CAD Simulation in Complex Orthopedic Surgery Practices"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4809-3536","authenticated-orcid":false,"given":"Leonardo","family":"Frizziero","sequence":"first","affiliation":[{"name":"Department of Industrial Engineering, ALMA MATER STUDIORUM University of Bologna, 40136 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Curzio","family":"Pagliari","sequence":"additional","affiliation":[{"name":"Department of Industrial Engineering, ALMA MATER STUDIORUM University of Bologna, 40136 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6666-1309","authenticated-orcid":false,"given":"Giampiero","family":"Donnici","sequence":"additional","affiliation":[{"name":"Department of Industrial Engineering, ALMA MATER STUDIORUM University of Bologna, 40136 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3255-9381","authenticated-orcid":false,"given":"Alfredo","family":"Liverani","sequence":"additional","affiliation":[{"name":"Department of Industrial Engineering, ALMA MATER STUDIORUM University of Bologna, 40136 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7966-6002","authenticated-orcid":false,"given":"Gian Maria","family":"Santi","sequence":"additional","affiliation":[{"name":"Department of Industrial Engineering, ALMA MATER STUDIORUM University of Bologna, 40136 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Papaleo","sequence":"additional","affiliation":[{"name":"Department of Industrial Engineering, ALMA MATER STUDIORUM University of Bologna, 40136 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Napolitano","sequence":"additional","affiliation":[{"name":"Department of Industrial Engineering, ALMA MATER STUDIORUM University of Bologna, 40136 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6430-4615","authenticated-orcid":false,"given":"Christian","family":"Leon-Cardenas","sequence":"additional","affiliation":[{"name":"Department of Industrial Engineering, ALMA MATER STUDIORUM University of Bologna, 40136 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0361-9920","authenticated-orcid":false,"given":"Giovanni","family":"Trisolino","sequence":"additional","affiliation":[{"name":"IRCCS Istituto Ortopedico Rizzoli (Rizzoli Ortopaedic Institute), Pediatric Orthopedics and Traumatology, 40136 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8135-0819","authenticated-orcid":false,"given":"Paola","family":"Zarantonello","sequence":"additional","affiliation":[{"name":"IRCCS Istituto Ortopedico Rizzoli (Rizzoli Ortopaedic Institute), Pediatric Orthopedics and Traumatology, 40136 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni Luigi","family":"Di Gennaro","sequence":"additional","affiliation":[{"name":"IRCCS Istituto Ortopedico Rizzoli (Rizzoli Ortopaedic Institute), Pediatric Orthopedics and Traumatology, 40136 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Stilli","sequence":"additional","affiliation":[{"name":"IRCCS Istituto Ortopedico Rizzoli (Rizzoli Ortopaedic Institute), Pediatric Orthopedics and Traumatology, 40136 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Stallone","sequence":"additional","affiliation":[{"name":"IRCCS Istituto Ortopedico Rizzoli (Rizzoli Ortopaedic Institute), Pediatric Orthopedics and Traumatology, 40136 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,5,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.21037\/atm.2016.12.24","article-title":"Innovations in surgery simulation: A review of past, current and future techniques","volume":"4","author":"Badash","year":"2016","journal-title":"Ann. 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