{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T21:11:38Z","timestamp":1770844298608,"version":"3.50.1"},"reference-count":47,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2021,9,5]],"date-time":"2021-09-05T00:00:00Z","timestamp":1630800000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Symmetry"],"abstract":"<jats:p>Ankyloses in the area of the temporomandibular joint (TMJ) are mentioned as a potential etiological factor of mandibular growth disorders and facial asymmetry. The aim of this case study was to evaluate the changes in the mandible of a child with zygomatic-coronoid ankylosis during the first five years of life, in which two adhesion release procedures were performed. The adopted symmetrical approach is based on the assumption of symmetry of the structure of the stomatognathic system in relation to the sagittal median plane. However, the assessment of pathological changes in the structure of the skeletal system was performed using an asymmetrical approach. Computed tomography techniques and a system of computer-aided diagnosis (CAD) were used in the case study. During the child\u2019s growth, linear and angular measurements were made thrice (at the age of 16, 25 and 54 months). The degree of asymmetry was estimated in the measurements made on the right and left sides of the three-dimensional mandible. Unilateral congenital hypoplasia of the articular process and zygomatic-coronoid adhesion caused asymmetrical growth of the mandible in the child along with shortening of the mandibular branch and body on the damaged side and a visible difference in the size of the mandibular angles. Removal of the adhesions during surgical procedures made it possible to reduce the asymmetry of the mandible and catch-up growth, although at the age of five, the mandible was still smaller than the mandible in healthy peers. It was shown that the early adhesion release procedures supported by the CAD analysis enabled the restoration of mandibular symmetry.<\/jats:p>","DOI":"10.3390\/sym13091634","type":"journal-article","created":{"date-parts":[[2021,9,6]],"date-time":"2021-09-06T23:55:22Z","timestamp":1630972522000},"page":"1634","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Evaluation of Mandibular Growth and Symmetry in Child with Congenital Zygomatic-Coronoid Ankylosis"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9182-6953","authenticated-orcid":false,"given":"Anna","family":"Lipowicz","sequence":"first","affiliation":[{"name":"Department of Anthropology, Institute of Environmental Biology, Wroclaw University of Environmental and Life Sciences, 50-375 Wroclaw, Poland"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4553-3479","authenticated-orcid":false,"given":"Wojciech","family":"Wola\u0144ski","sequence":"additional","affiliation":[{"name":"Department of Biomechatronics, Faculty of Biomedical Engineering, Silesian University of Technology, 41-800 Zabrze, Poland"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9313-0132","authenticated-orcid":false,"given":"Edyta","family":"Kawlewska","sequence":"additional","affiliation":[{"name":"Department of Biomechatronics, Faculty of Biomedical Engineering, Silesian University of Technology, 41-800 Zabrze, Poland"}]},{"given":"Patrycja","family":"Zwolska","sequence":"additional","affiliation":[{"name":"Aesthetical Dentistry Center \u201cStudio Dentico\u201d, 44-237 Stanowice, Poland"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6026-0010","authenticated-orcid":false,"given":"Ma\u0142gorzata","family":"Kulesa-Mrowiecka","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy, Institute of Physiotherapy, Faculty of Health Sciences, Jagiellonian University Medical College, 31-008 Cracow, Poland"}]},{"given":"Krzysztof","family":"Dowgierd","sequence":"additional","affiliation":[{"name":"Head and Neck Surgery Clinic for Children and Young Adults, Department of Clinical Pediatrics, University of Warmia and Mazury, 10-561 Olsztyn, Poland"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8542-8123","authenticated-orcid":false,"given":"Pawe\u0142","family":"Linek","sequence":"additional","affiliation":[{"name":"Institute of Physiotherapy and Health Sciences, Academy of Physical Education, 40-065 Katowice, Poland"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2183-1156","authenticated-orcid":false,"given":"Andrzej","family":"My\u015bliwiec","sequence":"additional","affiliation":[{"name":"Institute of Physiotherapy and Health Sciences, Academy of Physical Education, 40-065 Katowice, Poland"},{"name":"Specialized Physiotherapy Center, 44-270 Rybnik, Poland"}]}],"member":"1968","published-online":{"date-parts":[[2021,9,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1590\/2177-6709.20.6.110-125.sar","article-title":"Facial asymmetry: A current review","volume":"20","author":"Thiesen","year":"2015","journal-title":"Dent. Press J. Orthod."},{"key":"ref_2","first-page":"45","article-title":"Dental arch asymmetry in children with large overjets","volume":"68","author":"Kula","year":"1998","journal-title":"Angle Orthod."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1093\/ejo\/cjq057","article-title":"Prevalence of mandibular asymmetries in growing patients","volume":"33","author":"Stewart","year":"2011","journal-title":"Eur. J. Orthod."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"44","DOI":"10.12968\/ortu.2008.1.2.44","article-title":"The aetiology, diagnosis and management of mandibular asymmetry","volume":"1","author":"Chia","year":"2008","journal-title":"Orthod. Update"},{"key":"ref_5","first-page":"341","article-title":"Facial asymmetry: Etiology, evaluation, and management","volume":"34","author":"Cheong","year":"2011","journal-title":"Chang Gung Med. J."},{"key":"ref_6","first-page":"141","article-title":"An assessment of asymmetry in the normal craniofacial complex","volume":"48","author":"Shah","year":"1978","journal-title":"Angle Orthod."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"421","DOI":"10.2319\/022107-85.1","article-title":"Asymmetry of the face in orthodontic patients","volume":"78","author":"Haraguchi","year":"2008","journal-title":"Angle Orthod."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"3820","DOI":"10.1523\/JNEUROSCI.23-09-03820.2003","article-title":"Emotion processing in chimeric faces: Hemispheric asymmetries in expression and recognition of emotions","volume":"23","author":"Indersmitten","year":"2003","journal-title":"J. Neurosci."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/S0901-5027(05)80848-3","article-title":"Perspectives on craniofacial asymmetry. I. The biology of asymmetry","volume":"24","author":"Cohen","year":"1995","journal-title":"Int. J. Oral Maxillofac. Surg."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"dev193755","DOI":"10.1242\/dev.193755","article-title":"Symmetry and fluctuation of cell movements in neural crest-derived facial mesenchyme","volume":"148","author":"Danescu","year":"2021","journal-title":"Development"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1177\/154405910508401116","article-title":"The growth hormone receptor gene is associated with mandibular height in a Chinese population","volume":"84","author":"Zhou","year":"2005","journal-title":"J. Dent. Res."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"803","DOI":"10.2319\/091713-680.1","article-title":"Relationship between P561T and C422F polymorphisms in growth hormone receptor gene and mandibular prognathism","volume":"84","author":"Bayram","year":"2014","journal-title":"Angle Orthod."},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Pawlaczyk-Kamie\u0144ska, T., Kulczyk, T., Pawlaczyk-Wr\u00f3blewska, E., Borysewicz-Lewicka, M., and Niedziela, M. (2020). Limited mandi-bular movements as a consequence of unilateral or asymmetrical temporomandibular joint involvement in juvenile idiopathic arthritis patients. Clin. Med., 9.","DOI":"10.3390\/jcm9082576"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"650","DOI":"10.12998\/wjcc.v7.i5.650","article-title":"Application of computer-assisted navigation in treating congenital maxillomandibular syngnathia: A case report","volume":"7","author":"Lin","year":"2019","journal-title":"World J. Clin. Cases"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/0002-9416(86)90068-0","article-title":"Computer-aided modeling in the assessment of the biomechanical determination of diverse skeletal patterns","volume":"89","author":"Haskell","year":"1986","journal-title":"Am. J. Orthod."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.jdsr.2013.07.004","article-title":"Growth of the mandible and biological characteristics of the mandibular condylar cartilage","volume":"49","author":"Mizoguchi","year":"2013","journal-title":"Jpn. Dent. Sci. Rev."},{"key":"ref_17","first-page":"227","article-title":"Aetiology of temporomandibular joint ankylosis: Analysis of 44 cases","volume":"22","author":"Topazian","year":"1964","journal-title":"J. Oral Surg."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1966","DOI":"10.1016\/j.joms.2009.03.071","article-title":"A Protocol for Management of Temporomandibular Joint Ankylosis in Children","volume":"67","author":"Kaban","year":"2009","journal-title":"J. Oral Maxillofac. Surg."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S1010-5182(05)80536-0","article-title":"Congenital prearticular temporo-mandibular ankylosis in two siblings","volume":"18","author":"Domarus","year":"1990","journal-title":"J. Cranio-Maxillofac. Surg."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1001\/jama.1936.02770200025009","article-title":"Congenital bony temporomandibular ankylosis and facial hemiatrophy: Review of the literature and report of a case","volume":"106","author":"Burket","year":"1936","journal-title":"J. Am. Med. Assoc."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1111\/j.1601-6343.2007.00388.x","article-title":"Treacher Collins syndrome","volume":"10","author":"Dixon","year":"2007","journal-title":"Orthod. Craniofac. Res."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/ejo\/cjn117","article-title":"Abnormal mandibular growth and the condylar cartilage","volume":"31","author":"Pirttiniemi","year":"2009","journal-title":"Eur. J. Orthod."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/0889-5406(93)70027-L","article-title":"Pediatric internal derangement of the temporomandibular joint: Effect on facial development","volume":"104","author":"Schellhas","year":"1993","journal-title":"Am. J. Orthod."},{"key":"ref_24","first-page":"E66","article-title":"Treatment of temporomandibular joint ankylosis by gap arthrop-lasty","volume":"11","author":"Vasconcelos","year":"2006","journal-title":"Med. Oral Patol. Oral Cir. Bucal"},{"key":"ref_25","first-page":"324","article-title":"Mandibular growth following ankylosis operation in childhood","volume":"10","author":"Ohno","year":"1981","journal-title":"Int. J. Oral Surg."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/S1010-5182(89)80094-0","article-title":"Facial growth after treatment of unilateral temporomandibular joint ankylosis in childhood without growth centre transplantation. A serial cephalomorphometric study","volume":"17","author":"Farmand","year":"1989","journal-title":"J. Cranio-Maxillofac. Surg."},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Cheong, R.C.T., Kassam, K., Eccles, S., and Hensher, R. (2016). Congenital temporomandibular joint ankylosis: Case report and literature review. Case Rep. Otolaryngol., 5802359.","DOI":"10.1155\/2016\/5802359"},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Dowgierd, K., Lipowicz, A., Kulesa-Mrowiecka, M., Wola\u0144ski, W., Linek, P., and My\u015bliwiec, A. (2021). Efficacy of immediate physiotherapy after surgical release of zygomatico-coronoid ankylosis in a young child: A case report. Physiother. Theor. Pract.","DOI":"10.1080\/09593985.2021.1952672"},{"key":"ref_29","first-page":"211","article-title":"A new system of dental age assessment","volume":"45","author":"Demirjian","year":"1973","journal-title":"Hum. Biol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1016\/j.cad.2005.02.002","article-title":"Bio-CAD modelling and its applications in computer-aided tissue engineering","volume":"37","author":"Sun","year":"2005","journal-title":"Comput. Aided Des."},{"key":"ref_31","first-page":"35","article-title":"Morphological analysis of the skull shape in craniosynostosis","volume":"13","author":"Tejszerska","year":"2011","journal-title":"Acta Bioeng. Biomech."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"219","DOI":"10.2485\/jhtb.25.219","article-title":"Accuracy of three dimensional CT craniofacial measurements using Mimics and In Vesalius software programs","volume":"25","author":"Hasan","year":"2016","journal-title":"J. Hard Tissue Biol."},{"key":"ref_33","unstructured":"Martin, R., and Saller, K. (1957). Lehrbuch der Anthropologie, Band 1, Gustav Fischer Verlag."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1111\/j.1365-2842.1987.tb00742.x","article-title":"The orthopantomogram an aid in diagnosis of temporomandibular joint problems I. The factor of vertical magnification","volume":"14","author":"Habets","year":"1987","journal-title":"J. Oral Rehabil."},{"key":"ref_35","unstructured":"Malinowski, A. (2003). Ontogeneza \u017buchwy Ludzkiej, Wydawnictwo Uniwersytetu Zielonog\u00f3rskiego."},{"key":"ref_36","first-page":"161","article-title":"Assessment of age from early mandibular growth\u2014Case reports","volume":"5","author":"Kaur","year":"2016","journal-title":"Hum. Biol. Rev."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"233.e1","DOI":"10.1016\/j.forsciint.2011.11.014","article-title":"An assessment of early mandibular growth","volume":"217","author":"Hutchinson","year":"2012","journal-title":"Forensic Sci. Int."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.ijporl.2004.10.010","article-title":"Cephalometric assessment of the mandibular growth pattern in mouth-breathing children","volume":"69","author":"Sousa","year":"2005","journal-title":"Int. J. Pediatric Otorhinolaryngol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"97","DOI":"10.2319\/020309-67.1","article-title":"Mandibular growth, remodeling, and maturation during infancy and early childhood","volume":"80","author":"Liu","year":"2010","journal-title":"Angle Orthod."},{"key":"ref_40","first-page":"95","article-title":"The role of the functional matrix in mandibular growth","volume":"38","author":"Moss","year":"1968","journal-title":"Angle Orthod."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"510","DOI":"10.3109\/03014460.2015.1106584","article-title":"Age and sex-related growth patterns of the craniofacial complex in European children aged 3\u20136 years","volume":"43","author":"Tutkuviene","year":"2016","journal-title":"Ann. Hum. Biol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"6042","DOI":"10.1038\/s41598-018-24293-3","article-title":"Human mandibular shape is associated with masticatory muscle force","volume":"8","author":"Pokhojaev","year":"2018","journal-title":"Sci. Rep."},{"key":"ref_43","first-page":"7","article-title":"Dimensional differences in mandibular antegonial notches in temporomandibular joint ankylosis","volume":"1","author":"Singh","year":"2011","journal-title":"JOBCR"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"27","DOI":"10.15713\/ins.jcri.253","article-title":"Catch-up growth after skeletal maturity\u2014A case report","volume":"6","author":"Hridaya","year":"2019","journal-title":"J. Adv. Clin. Res. Insights"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s13005-019-0200-1","article-title":"Mandibular growth in infants with Robin sequence treated with the T\u00fcbingen palatal plate","volume":"15","author":"Wiechers","year":"2019","journal-title":"Head Face Med."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1177\/00220345830620051301","article-title":"Occlusal forces in normal and long-face children","volume":"62","author":"Proffit","year":"1983","journal-title":"J. Dent. Res."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.earlhumdev.2008.12.003","article-title":"The development of jaw motion for mastication","volume":"85","author":"Wilson","year":"2009","journal-title":"Early Hum. Dev."}],"container-title":["Symmetry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2073-8994\/13\/9\/1634\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T06:56:55Z","timestamp":1760165815000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2073-8994\/13\/9\/1634"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,5]]},"references-count":47,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2021,9]]}},"alternative-id":["sym13091634"],"URL":"https:\/\/doi.org\/10.3390\/sym13091634","relation":{},"ISSN":["2073-8994"],"issn-type":[{"value":"2073-8994","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,5]]}}}