{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T20:09:04Z","timestamp":1776197344035,"version":"3.50.1"},"reference-count":37,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2022,2,2]],"date-time":"2022-02-02T00:00:00Z","timestamp":1643760000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012190","name":"Ministry of Science and Higher Education of the Russian Federation","doi-asserted-by":"publisher","award":["FEWM-2020-0042"],"award-info":[{"award-number":["FEWM-2020-0042"]}],"id":[{"id":"10.13039\/501100012190","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Symmetry"],"abstract":"<jats:p>Thermoablation is used in the treatment of tumorous bones. However, little is known about the influence such thermal treatment has on the mechanical properties of bone tissue. The purpose of this work was to study the influence of thermal treatment in a range of 60\u2013100 \u00b0C (in increments of 10 \u00b0C) on the structural properties of pig femurs using an original approach that involved a periosteal arrangement of heating elements providing gradual dry heating of the bone from its periphery to its center. Heating of freshly extracted bone tissue segments was performed ex vivo using surface heaters of a Phoenix-2 local hyperthermia hardware system. Mechanical testing followed the single-axis compression scheme (traverse velocity of 1 mm\/min). In the 60\u201390 \u00b0C range of heating, no attributes of reduced structural characteristics were found in the samples subjected to thermoablation in comparison to the control samples taken from symmetric areas of adjacent cylinders of healthy bones and not subjected to heat treatment. The following statistically significant changes were found as a result of compressing the samples to 100 \u00b0C after the heat treatment: reduced modulus of elasticity and increased elastic strain (strain-to-failure), mainly due to increases in plastic deformation. This finding may serve as evidence of a critical ex vivo change in the biomechanical behavior of bone tissues at such temperatures. Thus, ex vivo treatment of bone tissue in the thermal range of 60\u201390 \u00b0C may be used in studies of thermoablation efficiency against tumor involvement of bones.<\/jats:p>","DOI":"10.3390\/sym14020303","type":"journal-article","created":{"date-parts":[[2022,2,6]],"date-time":"2022-02-06T20:40:18Z","timestamp":1644180018000},"page":"303","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Compressive Strength Characteristics of Long Tubular Bones after Hyperthermal Ablation"],"prefix":"10.3390","volume":"14","author":[{"given":"Denis","family":"Pakhmurin","sequence":"first","affiliation":[{"name":"Laboratory of Acquisition, Analysis and Control of Biological Signals, Tomsk State University of Control Systems and Radioelectronics, 40 Lenina Str., 634050 Tomsk, Russia"},{"name":"Department of Morphology and General Pathology, Siberian State Medical University, 2 Moskovsky Trakt, 634050 Tomsk, Russia"},{"name":"Department of Medical Cybernetics, Siberian State Medical University, 2 Moskovsky Trakt, 634050 Tomsk, Russia"}]},{"given":"Viktoriya","family":"Pakhmurina","sequence":"additional","affiliation":[{"name":"Laboratory of Acquisition, Analysis and Control of Biological Signals, Tomsk State University of Control Systems and Radioelectronics, 40 Lenina Str., 634050 Tomsk, Russia"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1860-3654","authenticated-orcid":false,"given":"Alexander","family":"Kashin","sequence":"additional","affiliation":[{"name":"Institute of Strength Physics and Materials Science, Siberian Branch of Russian Academy of Sciences (ISPMS SB RAS), 2\/4 Akademicheskiy Str., 634055 Tomsk, Russia"}]},{"given":"Alexey","family":"Kulkov","sequence":"additional","affiliation":[{"name":"Institute of Strength Physics and Materials Science, Siberian Branch of Russian Academy of Sciences (ISPMS SB RAS), 2\/4 Akademicheskiy Str., 634055 Tomsk, Russia"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3465-8452","authenticated-orcid":false,"given":"Igor","family":"Khlusov","sequence":"additional","affiliation":[{"name":"Department of Morphology and General Pathology, Siberian State Medical University, 2 Moskovsky Trakt, 634050 Tomsk, Russia"},{"name":"Department of Medical Cybernetics, Siberian State Medical University, 2 Moskovsky Trakt, 634050 Tomsk, Russia"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8000-2716","authenticated-orcid":false,"given":"Evgeny","family":"Kostyuchenko","sequence":"additional","affiliation":[{"name":"Laboratory of Acquisition, Analysis and Control of Biological Signals, Tomsk State University of Control Systems and Radioelectronics, 40 Lenina Str., 634050 Tomsk, Russia"}]},{"given":"Ivan","family":"Sidorov","sequence":"additional","affiliation":[{"name":"Irkutsk Supercomputer Center of SB RAS, 134 Lermontova, 664033 Irkutsk, Russia"}]},{"given":"Ilya","family":"Anisenya","sequence":"additional","affiliation":[{"name":"Department of General Oncology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, 634009 Tomsk, Russia"}]}],"member":"1968","published-online":{"date-parts":[[2022,2,2]]},"reference":[{"key":"ref_1","unstructured":"(2021, November 29). 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