{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:37:12Z","timestamp":1770079032152,"version":"3.49.0"},"reference-count":142,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2010,5,25]],"date-time":"2010-05-25T00:00:00Z","timestamp":1274745600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Symmetry"],"abstract":"<jats:p>Current research focuses on a better understanding of the origin of biomolecular asymmetry by the identification and detection of the possibly first chiral molecules that were involved in the appearance and evolution of life on Earth. We have reasons to assume that these molecules were specific chiral amino acids. Chiral amino acids have been identified in both chondritic meteorites and simulated interstellar ices. Present research reasons that circularly polarized electromagnetic radiation was identified in interstellar environments and an asymmetric interstellar photon-molecule interaction might have triggered biomolecular symmetry breaking. We review on the possible prebiotic interaction of \u2018chiral photons\u2019 in the form of circularly polarized light, with early chiral organic molecules. We will highlight recent studies on enantioselective photolysis of racemic amino acids by circularly polarized light and experiments on the asymmetric photochemical synthesis of amino acids from only one C and one N containing molecules by simulating interstellar environments. Both approaches are based on circular dichroic transitions of amino acids that will be presented as well.<\/jats:p>","DOI":"10.3390\/sym2021055","type":"journal-article","created":{"date-parts":[[2010,5,25]],"date-time":"2010-05-25T16:59:51Z","timestamp":1274806791000},"page":"1055-1080","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Photochirogenesis: Photochemical Models on the Origin of Biomolecular Homochirality"],"prefix":"10.3390","volume":"2","author":[{"given":"Cornelia","family":"Meinert","sequence":"first","affiliation":[{"name":"Facult\u00e9 des Sciences, University of Nice-Sophia Antipolis, UMR 6001 CNRS, LCMBA, 28 Avenue Valrose, 06108 Nice, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Jacques","family":"Filippi","sequence":"additional","affiliation":[{"name":"Facult\u00e9 des Sciences, University of Nice-Sophia Antipolis, UMR 6001 CNRS, LCMBA, 28 Avenue Valrose, 06108 Nice, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurent","family":"Nahon","sequence":"additional","affiliation":[{"name":"Synchrotron SOLEIL, l\u2019Orme des Merisiers, Saint Aubin BP 48, 91192 Gif-sur-Yvette, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8018-5433","authenticated-orcid":false,"given":"S\u00f8ren V.","family":"Hoffmann","sequence":"additional","affiliation":[{"name":"Institute for Storage Ring Facilities (ISA), Aarhus University, Ny Munkegade 120, DK-8000 Aarhus C, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louis","family":"D\u2019Hendecourt","sequence":"additional","affiliation":[{"name":"Astrochimie et Origines, Institut d\u2019Astrophysique Spatiale (IAS), B\u00e2t. 121, Universit\u00e9 Paris-Sud, 91405 Orsay Cedex, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"De Marcellus","sequence":"additional","affiliation":[{"name":"Astrochimie et Origines, Institut d\u2019Astrophysique Spatiale (IAS), B\u00e2t. 121, Universit\u00e9 Paris-Sud, 91405 Orsay Cedex, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan Hendrik","family":"Bredeh\u00f6ft","sequence":"additional","affiliation":[{"name":"Institute for Applied and Physical Chemistry, University of Bremen, Leobener Str. NW2, 28359 Bremen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfram H.-P.","family":"Thiemann","sequence":"additional","affiliation":[{"name":"Institute for Applied and Physical Chemistry, University of Bremen, Leobener Str. NW2, 28359 Bremen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uwe J.","family":"Meierhenrich","sequence":"additional","affiliation":[{"name":"Facult\u00e9 des Sciences, University of Nice-Sophia Antipolis, UMR 6001 CNRS, LCMBA, 28 Avenue Valrose, 06108 Nice, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2010,5,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/BF01809580","article-title":"The origin and amplification of biomolecular chirality","volume":"21","author":"Bonner","year":"1991","journal-title":"Orig. Life Evol. 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