{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T03:23:40Z","timestamp":1775705020558,"version":"3.50.1"},"reference-count":299,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2016,12,16]],"date-time":"2016-12-16T00:00:00Z","timestamp":1481846400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Symmetry"],"abstract":"<jats:p>Fluctuating asymmetry, the random deviation from perfect symmetry, is a widely used population-level index of developmental instability, developmental noise, and robustness. It reflects a population\u2019s state of adaptation and genomic coadaptation. Here, we review the literature on fluctuating asymmetry of human populations. The most widely used bilateral traits include skeletal, dental, and facial dimensions; dermatoglyphic patterns and ridge counts; and facial shape. Each trait has its advantages and disadvantages, but results are most robust when multiple traits are combined into a composite index of fluctuating asymmetry (CFA). Both environmental (diet, climate, toxins) and genetic (aneuploidy, heterozygosity, inbreeding) stressors have been linked to population-level variation in fluctuating asymmetry. In general, these stressors increase average fluctuating asymmetry. Nevertheless, there have been many conflicting results, in part because (1) fluctuating asymmetry is a weak signal in a sea of noise; and (2) studies of human fluctuating asymmetry have not always followed best practices. The most serious concerns are insensitive asymmetry indices (correlation coefficient and coefficient of indetermination), inappropriate size scaling, unrecognized mixture distributions, inappropriate corrections for directional asymmetry, failure to use composite indices, and inattention to measurement error. Consequently, it is often difficult (or impossible) to compare results across traits, and across studies.<\/jats:p>","DOI":"10.3390\/sym8120154","type":"journal-article","created":{"date-parts":[[2016,12,16]],"date-time":"2016-12-16T10:55:28Z","timestamp":1481885728000},"page":"154","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":84,"title":["Fluctuating Asymmetry of Human Populations: A Review"],"prefix":"10.3390","volume":"8","author":[{"given":"John","family":"Graham","sequence":"first","affiliation":[{"name":"Biology Department, Berry College, Mount Berry, GA 30149, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bari\u015f","family":"\u00d6zener","sequence":"additional","affiliation":[{"name":"Department of Anthropology, Istanbul University, Istanbul 34452, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2016,12,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1017\/S0016672300011071","article-title":"Developmental \u2018noise\u2019 and a congenital malformation","volume":"10","author":"Adams","year":"1967","journal-title":"Genet. Res."},{"key":"ref_2","first-page":"626","article-title":"Dental asymmetry as an indicator of genetic and environmental conditions in human populations","volume":"42","author":"Bailit","year":"1970","journal-title":"Hum. Biol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1038\/hdy.1953.41","article-title":"Genetical control of stability in development","volume":"7","author":"Mather","year":"1953","journal-title":"Heredity"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"125","DOI":"10.2307\/2406192","article-title":"A study of fluctuating asymmetry","volume":"16","year":"1962","journal-title":"Evolution"},{"key":"ref_5","first-page":"183","article-title":"Analyse der erblichen St\u00f6rungsf\u00e4lle der bilateralen Symmetrie","volume":"55","author":"Astauroff","year":"1930","journal-title":"Zeitschrift f\u00fcr induktive Abstammungs Vererbungslehre"},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Ludwig, W. (1932). Das Rechts-Links Problem im Tierreich und heim Menschen, Springer-Verlag.","DOI":"10.1007\/978-3-662-29196-2"},{"key":"ref_7","unstructured":"Waddington, C.H. (1957). The Strategy of the Genes. A Discussion of Some Aspects of Theoretical Biology. With an Appendix by H. Kacser, George Allen Unwin."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1146\/annurev.es.17.110186.002135","article-title":"Fluctuating asymmetry: Measurement, analysis, patterns","volume":"17","author":"Palmer","year":"1986","journal-title":"Annu. Rev. Ecol. Syst."},{"key":"ref_9","first-page":"7","article-title":"Population phenogenetics: Analysis of developmental stability in natural populations","volume":"191","author":"Zakharov","year":"1992","journal-title":"Acta Zool. Fenn."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1111\/j.1420-9101.2006.01175.x","article-title":"Fluctuating asymmetry and developmental instability in evolutionary biology: Past, present and future","volume":"19","year":"2006","journal-title":"J. Evol. Biol."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Polak, M. (2003). Developmental Instability: Causes and Consequences, Oxford University Press.","DOI":"10.1093\/oso\/9780195143454.001.0001"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"466","DOI":"10.3390\/sym2020466","article-title":"Fluctuating asymmetry: Methods, theory, and applications","volume":"2","author":"Graham","year":"2010","journal-title":"Symmetry"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/j.1469-185X.1990.tb01186.x","article-title":"Fluctuating asymmetry: An epigenetic measure of stress","volume":"65","author":"Parsons","year":"1990","journal-title":"Biol. Rev."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1038\/hdy.1992.51","article-title":"Fluctuating asymmetry: A biological monitor of environmental and genomic stress","volume":"68","author":"Parsons","year":"1992","journal-title":"Heredity"},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Polak, M. (2003). Developmental Instability: Causes and Consequences, Oxford University Press.","DOI":"10.1093\/oso\/9780195143454.001.0001"},{"key":"ref_16","first-page":"136","article-title":"Developmental stability: A sensitive indicator of populations under stress","volume":"Volume STP1179","author":"Landis","year":"1993","journal-title":"Environmental Toxicology and Risk Assessment"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/BF02424507","article-title":"Nonlinear growth dynamics and the origin of fluctuating asymmetry","volume":"89","author":"Emlen","year":"1993","journal-title":"Genetica"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"358","DOI":"10.2307\/2640773","article-title":"Genetics of fluctuating asymmetry: A developmental model of developmental instability","volume":"53","author":"Klingenberg","year":"1999","journal-title":"Evolution"},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Graham, J.H., Robb, D.T., and Poe, A.R. (2012). Random phenotypic variation of yeast (Saccharomyces cerevisiae) single-gene knockouts fits a double pareto-lognormal distribution. PLoS ONE, 7.","DOI":"10.1371\/journal.pone.0048964"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.tig.2009.07.005","article-title":"Robustness: Mechanisms and consequences","volume":"25","author":"Masel","year":"2009","journal-title":"Trends Genet."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1146\/annurev-ecolsys-120213-091705","article-title":"On the nature and evolutionary impact of phenotypic robustness mechanisms","volume":"45","author":"Siegal","year":"2014","journal-title":"Annu. Rev. Ecol. Evol. Syst."},{"key":"ref_22","first-page":"57","article-title":"Fluctuating asymmetry as a measure of developmental stability: Implications of non-normal distributions and power of statistical tests","volume":"191","author":"Palmer","year":"1992","journal-title":"Acta Zool. Fenn."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Polak, M. (2003). Developmental Instability: Causes and Consequences, Oxford University Press.","DOI":"10.1093\/oso\/9780195143454.001.0001"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1093\/biomet\/87.2.285","article-title":"Statistical assessment of bilateral symmetry of shapes","volume":"87","author":"Mardia","year":"2000","journal-title":"Biometrika"},{"key":"ref_25","first-page":"1909","article-title":"Shape analysis of symmetric structures: Quantifying variation among individuals and asymmetry","volume":"56","author":"Klingenberg","year":"2002","journal-title":"Evolution"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"843","DOI":"10.3390\/sym7020843","article-title":"Analyzing fluctuating asymmetry with geometric morphometrics: Concepts, methods, and applications","volume":"7","author":"Klingenberg","year":"2015","journal-title":"Symmetry"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S1361-8415(97)85012-8","article-title":"Landmark methods for forms without landmarks: Morphometrics of group differences in outline shape","volume":"1","author":"Bookstein","year":"1997","journal-title":"Med. Image Anal."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.2307\/2411306","article-title":"Geometric morphometrics of developmental instability: Analyzing patterns of fluctuating asymmetry with Procrustes methods","volume":"52","author":"Klingenberg","year":"1998","journal-title":"Evolution"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1111\/joa.12252","article-title":"An investigation of matching symmetry in the human pinnae with possible implications for 3D ear recognition and sound localization","volume":"226","author":"Claes","year":"2015","journal-title":"J. Anat."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.1469-7580.2012.01528.x","article-title":"Sexual dimorphism in multiple aspects of 3D facial symmetry and asymmetry defined by spatially dense geometric morphometrics","volume":"221","author":"Claes","year":"2012","journal-title":"J. Anat."},{"key":"ref_31","unstructured":"Schlager, S. (2013). Soft-tissue Reconstruction of the Human Nose. [Ph.D. Thesis, Albert-Ludwigs-Universit\u00e4t]."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1002\/ajpa.22749","article-title":"Analysis of the human osseous nasal shape\u2014Population differences and sexual dimorphism","volume":"157","author":"Schlager","year":"2015","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1109\/34.476508","article-title":"Symmetry as a continuous feature","volume":"17","author":"Zabrodsky","year":"1995","journal-title":"IEEE Trans. Pattern Anal."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"255","DOI":"10.3390\/sym7010255","article-title":"Fluctuating asymmetry of plant leaves: Batch processing with LAMINA and Continuous Symmetry Measures","volume":"7","author":"Graham","year":"2015","journal-title":"Symmetry"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"7843","DOI":"10.1021\/ja00046a033","article-title":"Continuous symmetry measures","volume":"114","author":"Zabrodsky","year":"1992","journal-title":"J. Am. Chem. Soc."},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Markow, T.A. (1994). Developmental Instability: Its Origins and Evolutionary Implications, Kluwer.","DOI":"10.1007\/978-94-011-0830-0"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1111\/j.1469-1809.1959.tb01487.x","article-title":"The correlations between ridge-counts on different fingers estimated from a population sample","volume":"23","author":"Holt","year":"1959","journal-title":"Ann. Hum. Genet."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1192\/bjp.160.4.467","article-title":"Dermatoglyphic evidence of fluctuating asymmetry in schizophrenia","volume":"160","author":"Mellor","year":"1992","journal-title":"Br. J. Psychiat."},{"key":"ref_39","first-page":"337","article-title":"Quantifying fluctuating asymmetry\u2014Not all methods are equivalent","volume":"46","author":"Angus","year":"1982","journal-title":"Growth"},{"key":"ref_40","first-page":"1055","article-title":"Dermatoglyphics in patients with schizophrenia","volume":"16","author":"Shakibaei","year":"2011","journal-title":"J. Res. Med. Sci."},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Bookstein, F.L. (1997). Morphometric Tools for Landmark Data, Cambridge University Press.","DOI":"10.2307\/2534038"},{"key":"ref_42","first-page":"1","article-title":"3D morphometry aids facial analysis of individuals with a childhood cancer","volume":"9999A","author":"Hopman","year":"2016","journal-title":"Am. J. Med. Genet. A"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1046\/j.1095-8312.2003.00220.x","article-title":"Growth models and the expected distribution of fluctuating asymmetry","volume":"80","author":"Graham","year":"2003","journal-title":"Biol. J. Linn. Soc."},{"key":"ref_44","unstructured":"Crow, E.L., and Shimizu, K. (1988). Lognormal Distributions: Theory and Applications, Marcel Dekker."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1111\/j.1469-1809.1952.tb02513.x","article-title":"Genetics of dermal ridges: Bilateral asymmetry in finger ridge-counts","volume":"17","author":"Holt","year":"1952","journal-title":"Ann. Eugenic."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/(SICI)1096-8644(199809)107:1<125::AID-AJPA10>3.0.CO;2-2","article-title":"Fluctuating asymmetry and morphometric variation of hand bones","volume":"107","author":"Livshits","year":"1998","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"804","DOI":"10.2466\/25.10.PMS.120v16x3","article-title":"Evaluation of bilateral asymmetry between upper limb masses in right-handed young adults of both sexes","volume":"120","author":"Gutnik","year":"2015","journal-title":"Percept. Mot. Skills"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1095-8312.1998.tb01530.x","article-title":"Directional asymmetry and the measurement of developmental instability","volume":"64","author":"Graham","year":"1998","journal-title":"Biol. J. Linn. Soc."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.jhevol.2005.09.004","article-title":"Limb bone bilateral asymmetry: Variability and commonality among modern humans","volume":"50","author":"Auerbach","year":"2006","journal-title":"J. Hum. Evol."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1002\/ar.1091520213","article-title":"Bilateral asymmetry in weight and in length of human bones","volume":"152","author":"Latimer","year":"1965","journal-title":"Anat. Rec."},{"key":"ref_51","doi-asserted-by":"crossref","unstructured":"Macintosh, A.A., Pinhasi, R., and Stock, J.T. (2014). Divergence in male and female manipulative behaviors with the intensification of metallurgy in Central Europe. PLoS ONE, 9.","DOI":"10.1371\/journal.pone.0112116"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1002\/ar.23303","article-title":"Nasal septal deviation and facial skeletal asymmetries","volume":"299","author":"Hartman","year":"2016","journal-title":"Anat. Rec."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"511","DOI":"10.4103\/0976-3147.168436","article-title":"Frontal sinus asymmetry: Is it an effect of cranial asymmetry? X-ray analysis of 469 normal adult human frontal sinus","volume":"6","author":"Kanat","year":"2015","journal-title":"J. Neurosci. Rural Pract."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.intell.2007.07.001","article-title":"Fluctuating asymmetry and general intelligence: No genetic or phenotypic association","volume":"36","author":"Johnson","year":"2008","journal-title":"Intelligence"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1046\/j.1461-0248.1999.00103.x","article-title":"Mixture analysis of asymmetry: Modelling directional asymmetry, antisymmetry and heterogeneity in fluctuating asymmetry","volume":"2","author":"Lens","year":"1999","journal-title":"Ecol. Lett."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s00784-009-0268-2","article-title":"The molecular mechanism behind bone remodelling: A review","volume":"13","author":"Proff","year":"2009","journal-title":"Clin. Oral Investig."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1023\/A:1020540418554","article-title":"Ontogenetic patterning of skeletal fluctuating asymmetry in rhesus macaques and humans: Evolutionary and developmental implications","volume":"20","year":"1999","journal-title":"Int. J. Primatol."},{"key":"ref_58","doi-asserted-by":"crossref","unstructured":"Palestis, B.G., and Trivers, R. (2016). A longitudinal study of changes in fluctuating asymmetry with age in Jamaican youth. Symmetry, 8.","DOI":"10.3390\/sym8110123"},{"key":"ref_59","doi-asserted-by":"crossref","unstructured":"Guatelli-Steinberg, D. (2016). What Teeth Reveal about Human Evolution, Cambridge University Press.","DOI":"10.1017\/CBO9781139979597"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"51","DOI":"10.2478\/anre-2013-0009","article-title":"Analysis of interaction between nutritional and developmental instability in mediaeval population in Wroc\u0142aw","volume":"76","author":"Szczurowski","year":"2013","journal-title":"Anthropol. Rev."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1146\/annurev-matsci-070909-104537","article-title":"Teeth: Among nature\u2019s most durable biocomposites","volume":"40","author":"Lawn","year":"2010","journal-title":"Annu. Rev. Mater. Res."},{"key":"ref_62","first-page":"390","article-title":"The effects of inbreeding on tooth size in Japanese children","volume":"17","author":"Niswander","year":"1965","journal-title":"Am. J. Hum. Genet."},{"key":"ref_63","first-page":"55","article-title":"The meaning of bilateral asymmetry in the permanent dentition","volume":"36","author":"Garn","year":"1966","journal-title":"Angle Orthod."},{"key":"ref_64","first-page":"186","article-title":"Buccolingual size asymmetry and its developmental meaning","volume":"37","author":"Garn","year":"1967","journal-title":"Angle Orthod."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1002\/ajpa.22107","article-title":"Revisiting dental fluctuating asymmetry in neandertals and modern humans","volume":"149","author":"Barrett","year":"2012","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"33","DOI":"10.26575\/daj.v16i2.158","article-title":"Dental asymmetry in a Late Archaic and late prehistoric skeletal sample of the Ohio Valley Area","volume":"16","author":"Sciulli","year":"2002","journal-title":"Dent. Anthropol."},{"key":"ref_67","unstructured":"Pietrusewsky, M., and Douglas, M.T. Database E.4 Individual Records of Measurements of Permanent Dentitions in Adolescents and Adults. Available online: https:\/\/core.tdar.org\/dataset\/376929\/database-e4-individual-records-of-measurements-of-permanent-dentitions-in-adolescents-and-adults."},{"key":"ref_68","unstructured":"Varner, T.B. (2015). Landmark-Based Approach to Examining Changes in Arch Shape: A Longitudinal Study. [Master\u2019s Thesis, University of Iowa]."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1037\/0735-7036.108.3.233","article-title":"Human (Homo sapiens) facial attractiveness and sexual selection: The role of symmetry and averageness","volume":"108","author":"Grammer","year":"1994","journal-title":"J. Comp. Psychol."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1111\/joa.12182","article-title":"Exploratory genotype\u2013phenotype correlations of facial form and asymmetry in unaffected relatives of children with non-syndromic cleft lip and\/or palate","volume":"224","author":"Miller","year":"2014","journal-title":"J. Anat."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1002\/ajpa.1330090422","article-title":"Palmar and plantar epidermal ridge configurations (dermatoglyphics) in European-Americans","volume":"9","author":"Cummins","year":"1926","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_72","unstructured":"Cummins, H., and Midlo, C. (1961). Finger Prints, Palms and Soles: An Introduction to Dermatoglyphics, Dover Publications."},{"key":"ref_73","doi-asserted-by":"crossref","unstructured":"Galton, F. (1892). Finger Prints, Macmillan and Company.","DOI":"10.2307\/2842054"},{"key":"ref_74","unstructured":"Loesch, D.Z. (1983). Quantitative Dermatoglyphics: Classification, Genetics, and Pathology, Oxford University Press."},{"key":"ref_75","first-page":"95","article-title":"Embryologic development of epidermal ridges and their configurations","volume":"27","author":"Babler","year":"1991","journal-title":"Birth Defects Orig. Artic. Ser."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.jtbi.2004.12.020","article-title":"Fingerprint formation","volume":"235","author":"Newell","year":"2005","journal-title":"J. Theor. Biol."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1080\/03014469300002962","article-title":"Fluctuating dermatoglyphic asymmetry: Genetic and prenatal influences","volume":"20","author":"Arrieta","year":"1993","journal-title":"Ann. Hum. Biol."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/BF01065992","article-title":"Asymmetry of a\u2013b ridge count and behavioral discordance of monozygotic twins","volume":"17","author":"Rose","year":"1987","journal-title":"Behav. Genet."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1002\/bdrc.21026","article-title":"Using natural disasters to study the effects of prenatal maternal stress on child health and development","volume":"96","author":"King","year":"2012","journal-title":"Birth Defects Res. C"},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1017\/S0954579409000364","article-title":"Prenatal maternal stress from a natural disaster predicts dermatoglyphic asymmetry in humans","volume":"21","author":"King","year":"2009","journal-title":"Dev. Psychopathol."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1111\/j.1469-1809.1954.tb01260.x","article-title":"The distal triradius t on the hands of parents and sibs of mongol imbeciles","volume":"19","author":"Penrose","year":"1954","journal-title":"Ann. Hum. Genet."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1127\/anthranz\/51\/1993\/59","article-title":"Directional and fluctuating asymmetry in the palmar interdigital ridge-counts","volume":"51","author":"Jantz","year":"1993","journal-title":"Anthropol. Anz."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1080\/03014468000004611","article-title":"Dermatoglyphic asymmetry as a measure of canalization","volume":"7","author":"Jantz","year":"1980","journal-title":"Ann. Hum. Biol."},{"key":"ref_84","doi-asserted-by":"crossref","unstructured":"Wijerathne, B.T.B., Meier, R.J., Agampodi, T.C., and Agampodi, S.B. (2015). Dermatoglyphics in hypertension: A review. J. Physiol. Anthropol., 34.","DOI":"10.1186\/s40101-015-0065-3"},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1142\/S0218001408006375","article-title":"Determining the association between dermatoglyphics and schizophrenia by using fingerprint asymmetry measures","volume":"22","author":"Wang","year":"2008","journal-title":"Int. J. Pattern Recogn."},{"key":"ref_86","first-page":"968134","article-title":"Mild dermatoglyphic deviations in adolescents with autism spectrum disorders and average intellectual abilities as compared to typically developing boys","volume":"2014","author":"Graham","year":"2014","journal-title":"Autism Res. Treat."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/0165-1781(86)90125-3","article-title":"Fluctuating dermatoglyphic asymmetry and the genetics of liability to schizophrenia","volume":"19","author":"Markow","year":"1986","journal-title":"Psychiatry Res."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1111\/j.1469-1809.1958.tb01426.x","article-title":"Genetics of dermal ridges: The relation between total ridge-count and the variability of counts from finger to finger","volume":"22","author":"Holt","year":"1958","journal-title":"Ann. Hum. Genet."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/j.1469-1809.1960.tb01737.x","article-title":"Genetics of dermal ridges: Familial correlations for (S\/\u221a10), a measurement of the diversity of ridge-counts from finger to finger","volume":"24","author":"Holt","year":"1960","journal-title":"Ann. Hum. Genet."},{"key":"ref_90","first-page":"485","article-title":"Dermatoglyphic sexual dimorphism in Israelis: Principal components and discriminant analyses applied to quantitative traits","volume":"58","author":"Micle","year":"1986","journal-title":"Hum. Biol."},{"key":"ref_91","first-page":"167","article-title":"Sexual dimorphism: Asymmetry and diversity of 38 dermatoglyphic traits in five endogamous populations of West Bengal, India","volume":"25","author":"Karmakar","year":"2001","journal-title":"Coll. Antropol."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"179","DOI":"10.4103\/0970-4388.19005","article-title":"Dermatoglyphic peculiarities in children with oral clefts","volume":"23","author":"Mathew","year":"2005","journal-title":"J. Indian Soc. Ped. Prev. Dent."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF02983100","article-title":"Studies on papillary patterns of human fingers","volume":"15","author":"Bonnevie","year":"1924","journal-title":"J. Genet."},{"key":"ref_94","first-page":"205","article-title":"Dermatoglyphic fluctuating asymmetry and symmetry in familial and non familial schizophrenia","volume":"39","author":"Ponnudurai","year":"1997","journal-title":"Indian J. Psychiatry"},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"149","DOI":"10.4103\/0971-6866.19535","article-title":"Fluctuating asymmetry in dermatoglyphics of non-insulin-dependent diabetes mellitus in Bangalore-based population","volume":"11","author":"Ravindranath","year":"2005","journal-title":"Indian J. Hum. Genet."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-244X-3-3","article-title":"Directional and fluctuating asymmetry in finger and ab ridge counts in psychosis: A case-control study","volume":"3","author":"Saha","year":"2003","journal-title":"BMC Psychiatry"},{"key":"ref_97","unstructured":"Russak, O. (2015). Dermatoglyphic Asymmetries, Symptoms, and Cognitive Function in Adolescents at Ultrahigh-risk for Psychotic Disorders. [Bachelor\u2019s Thesis, University of Colorado]."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.schres.2015.12.013","article-title":"Fluctuating dermatoglyphic asymmetries in youth at ultrahigh-risk for psychotic disorders","volume":"170","author":"Russak","year":"2016","journal-title":"Schizophr. Res."},{"key":"ref_99","first-page":"5","article-title":"Fluctuating asymmetry in dermatoglyphic traits in schizophrenic patients","volume":"49","author":"Sivkov","year":"2007","journal-title":"Folia Med."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0379-0738(99)00037-7","article-title":"Is there a gender difference in fingerprint ridge density?","volume":"102","author":"Acree","year":"1999","journal-title":"Forensic Sci. Int."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1038\/35107134","article-title":"Asymmetric Broca\u2019s area in great apes","volume":"414","author":"Cantalupo","year":"2001","journal-title":"Nature"},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1080\/13576500143000122","article-title":"Fluctuating asymmetry and the human brain","volume":"7","author":"Thoma","year":"2002","journal-title":"Laterality"},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1037\/0894-4105.11.4.552","article-title":"Developmental instability and cerebral lateralization","volume":"11","author":"Yeo","year":"1997","journal-title":"Neuropsychology"},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1016\/j.cortex.2007.08.022","article-title":"Believing in paranormal phenomena: Relations to asymmetry of body and brain","volume":"44","author":"Schulter","year":"2008","journal-title":"Cortex"},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0162-3095(97)00002-0","article-title":"Breast asymmetry and phenotypic quality in women","volume":"18","author":"Manning","year":"1997","journal-title":"Evol. Hum. Behav."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0162-3095(96)00001-5","article-title":"Asymmetry and the menstrual cycle in women","volume":"17","author":"Manning","year":"1996","journal-title":"Ethol. Sociobiol."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/1757-1146-6-27","article-title":"Geometric morphometric footprint analysis of young women","volume":"6","author":"Domjanic","year":"2013","journal-title":"J. Foot Ankle Res."},{"key":"ref_108","first-page":"261","article-title":"Sliding semi-landmarks on symmetric structures in three dimensions","volume":"147","author":"Schlager","year":"2012","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1139\/z95-231","article-title":"Fluctuating asymmetry and fractal dimension of the sagittal suture as indicators of inbreeding depression in dama and dorcas gazelles","volume":"73","author":"Alados","year":"1995","journal-title":"Can. J. Zool."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"310","DOI":"10.2307\/3545661","article-title":"Fractal structures and fractal functions as disease indicators","volume":"74","author":"Escos","year":"1995","journal-title":"Oikos"},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/BF00116422","article-title":"Developmental stability and its applications in ecotoxicology","volume":"2","author":"Graham","year":"1993","journal-title":"Ecotoxicology"},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.archoralbio.2003.09.010","article-title":"The mesiodistal crown diameters of primary dentition in Indonesian Javanese children","volume":"49","author":"Kuswandari","year":"2004","journal-title":"Arch. Oral Biol."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1002\/(SICI)1096-8644(199911)110:3<341::AID-AJPA6>3.0.CO;2-8","article-title":"Bilateral asymmetry in skeletal growth and maturation as an indicator of environmental stress","volume":"110","author":"Albert","year":"1999","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1002\/ajpa.22210","article-title":"Skull shape asymmetry and the socioeconomic structure of an early medieval central European society","volume":"150","author":"Bigoni","year":"2013","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1080\/03014460110112060","article-title":"Fluctuating asymmetry of a foraging population: The Hadza of Tanzania","volume":"29","author":"Gray","year":"2002","journal-title":"Ann. Hum. Biol."},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1002\/ajpa.20237","article-title":"Dental fluctuating asymmetry in the Gullah: Tests of hypotheses regarding developmental stability in deciduous vs permanent and male vs female teeth","volume":"129","author":"Sciulli","year":"2006","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_117","first-page":"547","article-title":"Multivariate fluctuating asymmetry in Israeli adults","volume":"65","author":"Livshits","year":"1993","journal-title":"Hum. Biol."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1002\/ajpa.21300","article-title":"Fluctuating and directional asymmetry in young human males: Effect of heavy working condition and socioeconomic status","volume":"143","year":"2010","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1093\/beheco\/arh099","article-title":"Are human preferences for facial symmetry focused on signals of developmental instability?","volume":"15","author":"Simmons","year":"2004","journal-title":"Behav. Ecol."},{"key":"ref_120","unstructured":"Trivers, R., Manning, J.T., Thornhill, R., Singh, D., and McGuire, M. (1999). Jamaican symmetry project: Long-term study of fluctuating asymmetry in rural Jamaican children. Hum. Biol., 417\u2013430."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1006\/jhev.1996.0041","article-title":"Fluctuating asymmetry and age in children: Evolutionary implications for the control of developmental stability","volume":"30","author":"Wilson","year":"1996","journal-title":"J. Hum. Evol."},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1002\/ajpa.1330610406","article-title":"Fluctuating asymmetry in molar dimensions and discrete morphological traits in Pima Indians","volume":"61","author":"Noss","year":"1983","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.evolhumbehav.2010.06.003","article-title":"Facial symmetry in young girls and boys from a slum and a control area of Ankara, Turkey","volume":"31","author":"Fink","year":"2010","journal-title":"Evol. Hum. Behav."},{"key":"ref_124","first-page":"54","article-title":"Sexually dimorphic human body fat distribution and second-to-fourth digit ratio","volume":"3","year":"2013","journal-title":"Eurasian J. Anthropol."},{"key":"ref_125","first-page":"94","article-title":"Cinsiyete \u00f6zg\u00fc v\u00fccut morfolojisi ile elin ikinci ve d\u00f6rd\u00fcnc\u00fc parmak uzunluk oranlar\u0131 aras\u0131ndaki ili\u015fki","volume":"1","year":"2012","journal-title":"\u0130nsanbilim Dergisi"},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S1090-5138(03)00084-9","article-title":"Second to fourth digit ratio and facial asymmetry","volume":"25","author":"Fink","year":"2004","journal-title":"Evol. Hum. Behav."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"541","DOI":"10.3390\/sym2020541","article-title":"Fluctuating asymmetry and steroid hormones: A review","volume":"2","author":"Benderlioglu","year":"2010","journal-title":"Symmetry"},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1002\/ajpa.21357","article-title":"Brief communication: Facial fluctuating asymmetry as a marker of sex differences of the response to phenotypic stresses","volume":"143","year":"2010","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/j.1467-8624.2009.01385.x","article-title":"The timing of prenatal exposure to maternal cortisol and psychosocial stress is associated with human infant cognitive development","volume":"81","author":"Davis","year":"2010","journal-title":"Child Dev."},{"key":"ref_130","unstructured":"Bogin, B. (1999). Patterns of Human Growth, Cambridge University Press."},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1080\/03014468600008651","article-title":"Fluctuating odontometric asymmetry in the Lengua Indians of Paraguay","volume":"13","author":"Kieser","year":"1986","journal-title":"Ann. Hum. Biol."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1002\/ajmg.1320290409","article-title":"Decreased developmental stability as assessed by fluctuating asymmetry of morphometric traits in preterm infants","volume":"29","author":"Livshits","year":"1988","journal-title":"Am. J. Med. Genet."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1080\/03014460110079464","article-title":"Anthropometric asymmetry in chronically undernourished children from Southern Mexico","volume":"29","author":"Little","year":"2002","journal-title":"Ann. Hum. Biol."},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/S1090-5138(99)00028-8","article-title":"Growth and fluctuating asymmetry of stepchildren","volume":"20","author":"Flinn","year":"1999","journal-title":"Evol. Hum. Behav."},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1080\/03014460500480391","article-title":"A trade-off between early growth rate and fluctuating asymmetry in Brazilian boys","volume":"33","author":"Wells","year":"2006","journal-title":"Ann. Hum. Biol."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"34","DOI":"10.3109\/03014460.2010.486770","article-title":"Relationship between shortness of final body height and fluctuating asymmetry in Turkish young males","volume":"38","year":"2011","journal-title":"Ann. Hum. Biol."},{"key":"ref_137","first-page":"693","article-title":"Biomechanical pressures and upper extremity asymmetry: A study on young laborers","volume":"31","year":"2007","journal-title":"Coll. Antropol."},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1002\/ajhb.22735","article-title":"Is the area of the orbital opening in humans related to climate?","volume":"27","author":"Tomaszewska","year":"2015","journal-title":"Am. J. Hum. Biol."},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/BF02424508","article-title":"Developmental stability in plants: Symmetries, stress and epigenesis","volume":"89","author":"Freeman","year":"1993","journal-title":"Genetica"},{"key":"ref_140","doi-asserted-by":"crossref","unstructured":"Wuytack, T., Samson, R., Wuyts, K., Adriaenssens, S., Kardel, F., and Verheyen, K. (2013). Do Leaf Characteristics of White Willow (Salix alba L.), Northern Red Oak (Quercus rubra L.), and Scots Pine (Pinus sylvestris L.) Respond Differently to Ambient Air Pollution and Other Environmental Stressors?. Water Air Soil Pollut., 224.","DOI":"10.1007\/s11270-013-1635-9"},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.1016\/j.envpol.2011.06.037","article-title":"The effect of air pollution and other environmental stressors on leaf fluctuating asymmetry and specific leaf area of Salix alba L.","volume":"159","author":"Wuytack","year":"2011","journal-title":"Environ. Poll."},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0269-7491(01)00281-0","article-title":"Response of fluctuating asymmetry to arsenic toxicity: Support for the developmental selection hypothesis","volume":"118","author":"Polak","year":"2002","journal-title":"Environ. Poll."},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.ecolind.2015.02.004","article-title":"Impact of sewage pollution on two species of sea urchins in the Mediterranean Sea (Cortiou, France): Radial asymmetry as a bioindicator of stress","volume":"54","author":"Savriama","year":"2015","journal-title":"Ecol. Indic."},{"key":"ref_144","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s11160-010-9178-2","article-title":"Fluctuating asymmetry and exogenous stress in fishes: A review","volume":"21","author":"Allenbach","year":"2011","journal-title":"Rev. Fish Biol. Fish."},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1016\/j.marpolbul.2015.09.038","article-title":"Fluctuating asymmetry as a pollution monitor: The Australian estuarine smooth toadfish Tetractenos glaber (Teleostei: Tetraodontidae)","volume":"101","author":"Lajus","year":"2015","journal-title":"Mar. Pollut. Bull."},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/s10750-015-2404-0","article-title":"Measuring the impacts of Roundup Original\u00ae on fluctuating asymmetry and mortality in a Neotropical tadpole","volume":"765","author":"Costa","year":"2016","journal-title":"Hydrobiologia"},{"key":"ref_147","doi-asserted-by":"crossref","unstructured":"Lazi\u0107, M.M., Kaliontzopoulou, A., Carretero, M.A., and Crnobrnja-Isailovi\u0107, J. (2013). Lizards from urban areas are more asymmetric: Using fluctuating asymmetry to evaluate environmental disturbance. PLoS ONE, 8.","DOI":"10.1371\/journal.pone.0084190"},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1046\/j.1365-2435.2000.00406.x","article-title":"Biomarkers and fluctuating asymmetry as indicators of pollution-induced stress in two hole-nesting passerines","volume":"14","author":"Eeva","year":"2000","journal-title":"Funct. Ecol."},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1016\/j.chemosphere.2013.05.056","article-title":"Chronic exposure to environmental stressors induces fluctuating asymmetry in shrews inhabiting protected Mediterranean sites","volume":"93","year":"2013","journal-title":"Chemosphere"},{"key":"ref_150","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.ecolind.2013.02.024","article-title":"The use of fluctuating asymmetry as a measure of environmentally induced developmental instability: A meta-analysis","volume":"30","author":"Beasley","year":"2013","journal-title":"Ecol. Indic."},{"key":"ref_151","doi-asserted-by":"crossref","unstructured":"Philp, R.B. (2015). Ecosystems and Human Health: Toxicology and Environmental Hazards, CRC Press.","DOI":"10.1201\/9781420032376"},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1080\/03014469200002342","article-title":"Fluctuating odontometric asymmetry and maternal alcohol consumption","volume":"19","author":"Kieser","year":"1992","journal-title":"Ann. Hum. Biol."},{"key":"ref_153","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000243963","article-title":"Dermatoglyphic asymmetry in fetal alcohol syndrome","volume":"64","author":"Wilber","year":"1993","journal-title":"Neonatology"},{"key":"ref_154","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.alcohol.2009.10.016","article-title":"Prenatal alcohol exposure alters the patterns of facial asymmetry","volume":"44","author":"Klingenberg","year":"2010","journal-title":"Alcohol"},{"key":"ref_155","first-page":"43","article-title":"Effects of prenatal exposure to tobacco smoke on developmental stability in children","volume":"14","author":"Kieser","year":"1994","journal-title":"J. Craniofac. Genet. Dev. Biol."},{"key":"ref_156","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1002\/(SICI)1096-8644(199701)102:1<133::AID-AJPA11>3.0.CO;2-1","article-title":"Dental asymmetry, maternal obesity, and smoking","volume":"102","author":"Kieser","year":"1997","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_157","unstructured":"Epstein, C.J. (2007). The Consequences of Chromosome Imbalance: Principles, Mechanisms, and Models, Cambridge University Press."},{"key":"ref_158","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0168-9525(00)02172-7","article-title":"Too much of a good thing: Mechanisms of gene action in Down syndrome","volume":"17","author":"Reeves","year":"2001","journal-title":"Trends Genet."},{"key":"ref_159","first-page":"97","article-title":"Development of human autosomal aneuploid phenotypes (with an emphasis on Down syndrome)","volume":"191","author":"Shapiro","year":"1992","journal-title":"Acta Zool. Fenn."},{"key":"ref_160","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1002\/ajmg.1320140206","article-title":"Down syndrome\u2014A disruption of homeostasis","volume":"14","author":"Shapiro","year":"1983","journal-title":"Am. J. Med. Genet."},{"key":"ref_161","unstructured":"Benda, C.E. (1969). Down\u2019s Syndrome: Mongolism and Its Management, Grune & Stratton."},{"key":"ref_162","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1038\/nrg1448","article-title":"Chromosome 21 and Down syndrome: From genomics to pathophysiology","volume":"5","author":"Antonarakis","year":"2004","journal-title":"Nat. Rev. Genet."},{"key":"ref_163","doi-asserted-by":"crossref","first-page":"4997","DOI":"10.1073\/pnas.91.11.4997","article-title":"Down syndrome phenotypes: The consequences of chromosomal imbalance","volume":"91","author":"Korenberg","year":"1994","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_164","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1016\/S0140-6736(03)12987-X","article-title":"Down\u2019s syndrome","volume":"361","author":"Roizen","year":"2003","journal-title":"Lancet"},{"key":"ref_165","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1177\/00220345700490025301","article-title":"Increased crown-size asymmetry in trisomy G","volume":"49","author":"Garn","year":"1970","journal-title":"J. Dent. Res."},{"key":"ref_166","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/ajpa.1330520203","article-title":"Fluctuating dental asymmetry: A measure of developmental instability in Down syndrome","volume":"52","author":"Barden","year":"1980","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_167","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1111\/j.1834-7819.1983.tb01068.x","article-title":"Fluctuating dental asymmetry in Down\u2019s syndrome","volume":"28","author":"Townsend","year":"1983","journal-title":"Aust. Dent. J."},{"key":"ref_168","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1002\/ajpa.22255","article-title":"Trisomy 21 and facial developmental instability","volume":"151","author":"Starbuck","year":"2013","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_169","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1203\/00006450-197303000-00002","article-title":"Palmar dermatoglyphics of Down\u2019s syndrome: Revisited","volume":"7","author":"Plato","year":"1973","journal-title":"Pediatr. Res."},{"key":"ref_170","doi-asserted-by":"crossref","first-page":"3703","DOI":"10.1038\/srep03703","article-title":"Higher limb asymmetry in deceased human fetuses and infants with aneuploidy","volume":"4","author":"Bots","year":"2014","journal-title":"Sci. Rep."},{"key":"ref_171","unstructured":"Hartl, D.L., and Ruvolo, M. (2011). Genetics, Jones & Bartlett Publishers."},{"key":"ref_172","doi-asserted-by":"crossref","unstructured":"Debat, V., Bloyer, S., Faradji, F., Gidaszewski, N., Navarro, N., Orozco-terWengel, P., Ribeiro, V., Schl\u00f6tterer, C., Deutsch, J.S., and Peronnet, F. (2011). Developmental stability: A major role for Cyclin G in Drosophila melanogaster. PLoS Genet., 7.","DOI":"10.1371\/journal.pgen.1002314"},{"key":"ref_173","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1038\/sj.hdy.6800637","article-title":"An epistatic genetic basis for fluctuating asymmetry of tooth size and shape in mice","volume":"94","author":"Leamy","year":"2005","journal-title":"Heredity"},{"key":"ref_174","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1146\/annurev.ecolsys.36.102003.152640","article-title":"The genetics and evolution of fluctuating asymmetry","volume":"36","author":"Leamy","year":"2005","journal-title":"Annu. Rev. Ecol. Evol. Syst."},{"key":"ref_175","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1046\/j.1365-2540.1998.00320.x","article-title":"Quantitative trait loci for fluctuating asymmetry of discrete skeletal characters in mice","volume":"80","author":"Leamy","year":"1998","journal-title":"Heredity"},{"key":"ref_176","first-page":"642","article-title":"An epistatic genetic basis for fluctuating asymmetry of mandible size in mice","volume":"56","author":"Leamy","year":"2002","journal-title":"Evolution"},{"key":"ref_177","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1038\/nrg2664","article-title":"The genetics of inbreeding depression","volume":"10","author":"Charlesworth","year":"2009","journal-title":"Nat. Rev. Genet."},{"key":"ref_178","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/S0169-5347(02)02489-8","article-title":"Inbreeding effects in wild populations","volume":"17","author":"Keller","year":"2002","journal-title":"Trends Ecol. Evol."},{"key":"ref_179","doi-asserted-by":"crossref","first-page":"3324","DOI":"10.1073\/pnas.97.7.3324","article-title":"Male\u2013male competition magnifies inbreeding depression in wild house mice","volume":"97","author":"Meagher","year":"2000","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_180","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1002\/zoo.1430130302","article-title":"Is inbreeding depression more severe in a stressful environment?","volume":"13","author":"Miller","year":"1994","journal-title":"Zoo Biol."},{"key":"ref_181","doi-asserted-by":"crossref","unstructured":"Bihlmeyer, N.A., Brody, J.A., Smith, A.V., Lunetta, K.L., Nalls, M., Smith, J.A., Tanaka, T., Davies, G., Yu, L., and Mirza, S.S. (2014). Genetic diversity is a predictor of mortality in humans. BMC Genet., 15.","DOI":"10.1186\/s12863-014-0159-7"},{"key":"ref_182","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1159\/000321772","article-title":"Time to get real: Investigating potential beneficial genetic aspects of consanguinity","volume":"14","author":"Bittles","year":"2011","journal-title":"Public Health Genom."},{"key":"ref_183","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/j.earlhumdev.2010.08.003","article-title":"The impact of consanguinity on neonatal and infant health","volume":"86","author":"Bittles","year":"2010","journal-title":"Early Hum. Dev."},{"key":"ref_184","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1023\/A:1013866608313","article-title":"The effect of inbreeding on fluctuating asymmetry in Scabiosa canescens (Dipsacaceae)","volume":"15","author":"Waldmann","year":"2001","journal-title":"Evol. Ecol."},{"key":"ref_185","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/hdy.1960.38","article-title":"Developmental stability in constant and fluctuating temperatures","volume":"14","author":"Beardmore","year":"1960","journal-title":"Heredity"},{"key":"ref_186","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1038\/hdy.2009.13","article-title":"The effect of inbreeding on fluctuating asymmetry of wing veins in two laboratory strains of Drosophila melanogaster","volume":"102","author":"Carter","year":"2009","journal-title":"Heredity"},{"key":"ref_187","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1098\/rspb.2000.1084","article-title":"A comparative study of ejaculate traits in three endangered ungulates with different levels of inbreeding: Fluctuating asymmetry as an indicator of reproductive and genetic stress","volume":"267","author":"Gomendio","year":"2000","journal-title":"Proc. R. Soc. Lond. B. Biol. Sci."},{"key":"ref_188","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1086\/284225","article-title":"Morphometric studies in inbred and hybrid house mice. V. Directional and fluctuating asymmetry","volume":"123","author":"Leamy","year":"1984","journal-title":"Am. Nat."},{"key":"ref_189","doi-asserted-by":"crossref","first-page":"674","DOI":"10.2307\/2408240","article-title":"Inbreeding in an island population of the great tit","volume":"35","author":"Scharloo","year":"1981","journal-title":"Evolution"},{"key":"ref_190","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1038\/hdy.1994.184","article-title":"Fluctuating asymmetry does not increase with moderate inbreeding in Drosophila melanogaster","volume":"73","author":"Fowler","year":"1994","journal-title":"Heredity"},{"key":"ref_191","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.1469-1795.2000.tb00234.x","article-title":"Can fluctuating asymmetry be used to detect inbreeding and loss of genetic diversity in endangered populations?","volume":"3","author":"Gilligan","year":"2000","journal-title":"Anim. Conserv."},{"key":"ref_192","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1046\/j.1420-9101.2000.00239.x","article-title":"Developmental stability in yellow dung flies (Scathophaga stercoraria): Fluctuating asymmetry, heterozygosity and environmental stress","volume":"13","author":"Hosken","year":"2000","journal-title":"J. Evol. Biol."},{"key":"ref_193","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/BF00216600","article-title":"Incest avoidance, fluctuating asymmetry, and the consequences of inbreeding in Iridomyrmex humilis, an ant with multiple queen colonies","volume":"33","author":"Keller","year":"1993","journal-title":"Behav. Ecol. Sociobiol."},{"key":"ref_194","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1046\/j.1420-9101.2003.00503.x","article-title":"Fluctuating asymmetry in a secondary sexual trait: No associations with individual fitness, environmental stress or inbreeding, and no heritability","volume":"16","author":"Kruuk","year":"2003","journal-title":"J. Evol. Biol."},{"key":"ref_195","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1046\/j.1420-9101.2000.00232.x","article-title":"Developmental instability and inbreeding in natural bird populations exposed to different levels of habitat disturbance","volume":"13","author":"Lens","year":"2000","journal-title":"J. Evol. Biol."},{"key":"ref_196","unstructured":"Smith, P., and Tchernov, E. (1992). Structure, Function and Evolution of Teeth, Freund Publishing House, Ltd."},{"key":"ref_197","first-page":"441","article-title":"Fluctuating asymmetry as a possible measure of developmental homeostasis in humans: A review","volume":"63","author":"Livshits","year":"1991","journal-title":"Hum. Biol."},{"key":"ref_198","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1080\/03014469300002792","article-title":"Inbreeding and developmental stability in a small human population","volume":"20","author":"Markow","year":"1993","journal-title":"Ann. Hum. Biol."},{"key":"ref_199","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1002\/ajhb.21046","article-title":"Effect of inbreeding depression on growth and fluctuating asymmetry in Turkish young males","volume":"22","year":"2010","journal-title":"Am. J. Hum. Biol."},{"key":"ref_200","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1002\/ajpa.22401","article-title":"Growth and fluctuating asymmetry of human newborns: Influence of inbreeding and parental education","volume":"153","author":"Graham","year":"2014","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_201","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1002\/ajpa.20224","article-title":"Dental arch asymmetry in an isolated Adriatic community","volume":"129","author":"Schaefer","year":"2006","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_202","doi-asserted-by":"crossref","first-page":"104","DOI":"10.2307\/2408520","article-title":"Genomic coadaptation and developmental stability within introgressed populations of Enneacanthus gloriosus and E. obesus (Pisces, Centrarchidae)","volume":"39","author":"Graham","year":"1985","journal-title":"Evolution"},{"key":"ref_203","doi-asserted-by":"crossref","first-page":"622","DOI":"10.2307\/2409915","article-title":"The genetic interpretation of inbreeding depression and outbreeding depression","volume":"45","author":"Lynch","year":"1991","journal-title":"Evolution"},{"key":"ref_204","doi-asserted-by":"crossref","first-page":"123","DOI":"10.2307\/1542494","article-title":"Outbreeding depression as a cost of dispersal in the harpacticoid copepod, Tigriopus californicus","volume":"181","author":"Brown","year":"1991","journal-title":"Biol. Bull."},{"key":"ref_205","doi-asserted-by":"crossref","unstructured":"Edmands, S. (1999). Heterosis and outbreeding depression in interpopulation crosses spanning a wide range of divergence. Evolution, 1757\u20131768.","DOI":"10.1111\/j.1558-5646.1999.tb04560.x"},{"key":"ref_206","doi-asserted-by":"crossref","first-page":"1814","DOI":"10.2307\/2409510","article-title":"Hybrid breakdown in developmental time in the copepod Tigriopus californicus","volume":"44","author":"Burton","year":"1990","journal-title":"Evolution"},{"key":"ref_207","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0165-7836(91)90095-W","article-title":"Heterosis and outbreeding depression: A multi-locus model and an application to salmon production","volume":"12","author":"Emlen","year":"1991","journal-title":"Fish. Res."},{"key":"ref_208","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0044-8486(98)00480-3","article-title":"Outbreeding depression in hybrids between odd- and even-broodyear pink salmon","volume":"173","author":"Gharrett","year":"1999","journal-title":"Aquaculture"},{"key":"ref_209","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1023\/B:EBFI.0000022888.28218.c1","article-title":"Outbreeding depression in hybrids between spatially separated pink salmon, Oncorhynchus gorbuscha, populations: Marine survival, homing ability, and variability in family size","volume":"69","author":"Gilk","year":"2004","journal-title":"Environ. Biol. Fishes"},{"key":"ref_210","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1068\/p6626","article-title":"Why are mixed-race people perceived as more attractive?","volume":"39","author":"Lewis","year":"2010","journal-title":"Perception"},{"key":"ref_211","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1068\/p7278","article-title":"Mixed-ethnicity face shape and attractiveness in humans","volume":"41","author":"Little","year":"2012","journal-title":"Perception"},{"key":"ref_212","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/ajpa.10182","article-title":"Canalization, developmental stability, and morphological integration in primate limbs","volume":"45","author":"Hallgrimsson","year":"2002","journal-title":"Yearb. Phys. Anthropol."},{"key":"ref_213","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1098\/rspb.1993.0012","article-title":"Fluctuating asymmetry, sexual selection and canine teeth in primates","volume":"251","author":"Manning","year":"1993","journal-title":"Proc. R. Soc. Lond. B. Biol. Sci."},{"key":"ref_214","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1098\/rspb.1994.0027","article-title":"Fluctuating asymmetry in gorilla canines: A sensitive indicator of environmental stress","volume":"255","author":"Manning","year":"1994","journal-title":"Proc. R. Soc. Lond. B. Biol. Sci."},{"key":"ref_215","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1002\/ajpa.20190","article-title":"Bilateral asymmetry in the limb bones of the chimpanzee (Pan troglodytes)","volume":"128","author":"Sarringhaus","year":"2005","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_216","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jhevol.2011.11.006","article-title":"Morphological evolution through integration: A quantitative study of cranial integration in Homo, Pan, Gorilla and Pongo","volume":"62","author":"Singh","year":"2012","journal-title":"J. Hum. Evol."},{"key":"ref_217","first-page":"898","article-title":"The relationship between fluctuating asymmetry and environmental variance in rhesus macaque skulls","volume":"59","author":"Willmore","year":"2005","journal-title":"Evolution"},{"key":"ref_218","first-page":"A18","article-title":"Dental asymmetry in South African australopithecines: A preliminary analysis of odontometric and morphological components","volume":"42","author":"Kegley","year":"2002","journal-title":"J. Hum. Evol."},{"key":"ref_219","unstructured":"\u0160trkalj, G., Pather, N., and Kramer, B. (2005). Voyages in Science: Essays by South African Anatomists in Honour of Phillip V. Tobias\u2019 80th Birthday, Content Solutions."},{"key":"ref_220","first-page":"489","article-title":"Fluctuating dental asymmetry in great apes, fossil hominins, and modern humans: Implications for changing stressors during human evolution","volume":"39","author":"Frederick","year":"2007","journal-title":"Acta Psychol. Sin."},{"key":"ref_221","first-page":"175","article-title":"The assessment of fluctuating odontometric asymmetry from incomplete hominid fossil data","volume":"44","author":"Kieser","year":"1986","journal-title":"Anthropol. Anz."},{"key":"ref_222","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.jhevol.2008.08.011","article-title":"Size, shape, and asymmetry in fossil hominins: The status of the LB1 cranium based on 3D morphometric analyses","volume":"57","author":"Baab","year":"2009","journal-title":"J. Hum. Evol."},{"key":"ref_223","doi-asserted-by":"crossref","first-page":"11967","DOI":"10.1073\/pnas.1407382111","article-title":"Evolved developmental homeostasis disturbed in LB1 from Flores, Indonesia, denotes Down syndrome and not diagnostic traits of the invalid species Homo floresiensis","volume":"111","author":"Henneberg","year":"2014","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_224","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1002\/ajpa.1330410307","article-title":"Neandertal dental asymmetry and the probable mutation effect","volume":"41","author":"Suarez","year":"1974","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_225","doi-asserted-by":"crossref","unstructured":"Baab, K.L., Brown, P., Falk, D., Richtsmeier, J.T., Hildebolt, C.F., Smith, K., and Jungers, W. (2016). A critical evaluation of the Down syndrome diagnosis for LB1, type specimen of Homo floresiensis. PLoS ONE, 11.","DOI":"10.1371\/journal.pone.0155731"},{"key":"ref_226","doi-asserted-by":"crossref","unstructured":"R\u00edos, L., Rosas, A., Estalrrich, A., Garc\u00eda-Tabernero, A., Bastir, M., Huguet, R., Pastor, F., Sanch\u00eds-Gimeno, J.A., and de la Rasilla, M. (2015). Possible further evidence of low genetic diversity in the El Sidr\u00f3n (Asturias, Spain) Neandertal group: Congenital clefts of the atlas. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0136550"},{"key":"ref_227","doi-asserted-by":"crossref","unstructured":"S\u00e1nchez-Quinto, F., and Lalueza-Fox, C. (2015). Almost 20 years of Neanderthal palaeogenetics: Adaptation, admixture, diversity, demography and extinction. Philos. Trans. R. Soc. Lond. B. Biol. Sci., 370.","DOI":"10.1098\/rstb.2013.0374"},{"key":"ref_228","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/ajpa.1330460116","article-title":"On the meaning of increased fluctuating dental asymmetry: A cross populational study","volume":"46","author":"Doyle","year":"1977","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_229","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1002\/ajpa.1330480113","article-title":"Stress and dental asymmetry in a population of Japanese children","volume":"48","author":"Dibennardo","year":"1978","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_230","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1002\/ajpa.1330470114","article-title":"Fluctuating dental asymmetry: Variation among skeletal populations","volume":"47","author":"Perzigian","year":"1977","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_231","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1046\/j.1420-9101.1997.10010039.x","article-title":"Fluctuating asymmetry and developmental stability: Heritability of observable variation vs. heritability of inferred cause","volume":"10","author":"Palmer","year":"1997","journal-title":"J. Evol. Biol."},{"key":"ref_232","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1080\/713754380","article-title":"Handedness in past human populations: Skeletal markers","volume":"5","author":"Steele","year":"2000","journal-title":"Laterality"},{"key":"ref_233","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1002\/ajpa.22211","article-title":"No skeletal dysplasia in the Nariokotome boy KNM-WT 15000 (Homo erectus)\u2014A reassessment of congenital pathologies of the vertebral column","volume":"150","author":"Schiess","year":"2013","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_234","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/ajpa.1330930102","article-title":"Postcranial robusticity in Homo. II: Humeral bilateral asymmetry and bone plasticity","volume":"93","author":"Trinkaus","year":"1994","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_235","unstructured":"Hershkovitz, I. (1989). People and Culture in Change, British Archeological Reports International Series."},{"key":"ref_236","unstructured":"Cohen, M.N., and Armelagos, G.J. (1984). Paleopathology at the Origins of Agriculture, University Press of Florida."},{"key":"ref_237","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1002\/ajpa.20892","article-title":"Temporal variation and interaction between nutritional and developmental instability in prehistoric Japanese populations","volume":"137","author":"Hoover","year":"2008","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_238","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1002\/ajpa.20549","article-title":"Fluctuating asymmetry and stress in a medieval Nubian population","volume":"132","author":"DeLeon","year":"2007","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_239","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1002\/ajpa.1123","article-title":"Articular area responses to mechanical loading: Effects of exercise, age, and skeletal location","volume":"116","author":"Lieberman","year":"2001","journal-title":"Am. J. Phys. Anthropol."},{"key":"ref_240","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1002\/ajpa.20155","article-title":"The aging of Wolff\u2019s \u201claw\u201d: Ontogeny and responses to mechanical loading in cortical bone","volume":"47","author":"Pearson","year":"2004","journal-title":"Yearb. Phys. Anthropol."},{"key":"ref_241","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1002\/(SICI)1097-0185(19990601)255:2<162::AID-AR6>3.0.CO;2-1","article-title":"Joint anatomy, design, and arthroses: Insights of the Utah paradigm","volume":"255","author":"Frost","year":"1999","journal-title":"Anat. Record"},{"key":"ref_242","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1006\/jtbi.1999.1025","article-title":"A chondral modeling theory revisited","volume":"201","author":"Hamrick","year":"1999","journal-title":"J. Theor. Biol."},{"key":"ref_243","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1002\/ajhb.20023","article-title":"Bilateral variation in limb articular surface dimensions","volume":"16","author":"Plochocki","year":"2004","journal-title":"Am. J. Hum. Biol."},{"key":"ref_244","first-page":"19","article-title":"Lateral asymmetry of human long bones","volume":"9","year":"2001","journal-title":"Var. Evol."},{"key":"ref_245","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1002\/(SICI)1099-1212(199901\/02)9:1<18::AID-OA455>3.0.CO;2-A","article-title":"Directional asymmetry in the human clavicle","volume":"9","author":"Mays","year":"1999","journal-title":"Int. J. Osteoarchaeol."},{"key":"ref_246","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1002\/oa.633","article-title":"Directional bilateral asymmetry in human sacral morphology","volume":"12","author":"Plochocki","year":"2002","journal-title":"Int. J. Osteoarchaeol."},{"key":"ref_247","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1098\/rspb.1996.0125","article-title":"The heritability of fluctuating asymmetry and the genetic control of developmental stability","volume":"263","author":"Whitlock","year":"1996","journal-title":"Proc. R. Soc. Lond. B. Biol. Sci."},{"key":"ref_248","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1098\/rspb.1998.0453","article-title":"The repeatability of fluctuating asymmetry: A revision and extension","volume":"265","author":"Whitlock","year":"1998","journal-title":"Proc. R. Soc. Lond. B. Biol. Sci."},{"key":"ref_249","doi-asserted-by":"crossref","unstructured":"Polak, M. (2003). Developmental Instability: Causes and Consequences, Oxford University Press.","DOI":"10.1093\/oso\/9780195143454.001.0001"},{"key":"ref_250","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1086\/314104","article-title":"Within- and among-individual variation in fluctuating asymmetry of leaves in the fig (Ficus carica L.)","volume":"160","author":"Cowart","year":"1999","journal-title":"Int. J. Plant Sci."},{"key":"ref_251","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1086\/303298","article-title":"Fluctuating asymmetry as a bioindicator of stress: Comparing efficacy of analyses involving multiple traits","volume":"155","author":"Leung","year":"2000","journal-title":"Am. Nat."},{"key":"ref_252","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/S1364-6613(99)01403-5","article-title":"Facial attractiveness","volume":"3","author":"Thornhill","year":"1999","journal-title":"Trends Cogn. Sci."},{"key":"ref_253","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1086\/286110","article-title":"Bilateral symmetry and sexual selection: A meta-analysis","volume":"151","author":"Thornhill","year":"1998","journal-title":"Am. Nat."},{"key":"ref_254","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1086\/303223","article-title":"Detecting publication bias in meta-analyses: A case study of fluctuating asymmetry and sexual selection","volume":"154","author":"Palmer","year":"1999","journal-title":"Am. Nat."},{"key":"ref_255","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1086\/303233","article-title":"The biological significance of fluctuating asymmetry and sexual selection: A reply to Palmer","volume":"154","author":"Thornhill","year":"1999","journal-title":"Am. Nat."},{"key":"ref_256","doi-asserted-by":"crossref","first-page":"317","DOI":"10.3109\/03014460.2010.544676","article-title":"Associations between asymmetry and human attractiveness: Possible direct effects of asymmetry and signatures of publication bias","volume":"38","year":"2011","journal-title":"Ann. Hum. Biol."},{"key":"ref_257","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.evolhumbehav.2011.03.002","article-title":"Human fluctuating asymmetry in relation to health and quality: A meta-analysis","volume":"32","author":"Gangestad","year":"2011","journal-title":"Evol. Hum. Behav."},{"key":"ref_258","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1007\/s10508-012-9917-7","article-title":"Fluctuating asymmetry and masculinity\/femininity in humans: A meta-analysis","volume":"41","year":"2012","journal-title":"Arch. Sex. Behav."},{"key":"ref_259","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1037\/h0099207","article-title":"The relationship between sex-typical body shape and quality indicators","volume":"7","author":"Sim","year":"2013","journal-title":"J. Soc. Evol. Cult. Psychol."},{"key":"ref_260","doi-asserted-by":"crossref","first-page":"205","DOI":"10.3109\/03014460.2013.847120","article-title":"Associations among facial masculinity, physical strength, fluctuating asymmetry and attractiveness in young men and women","volume":"41","year":"2014","journal-title":"Ann. Hum. Biol."},{"key":"ref_261","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S1090-5138(01)00099-X","article-title":"The sound of symmetry: Voice as a marker of developmental instability","volume":"23","author":"Hughes","year":"2002","journal-title":"Evol. Hum. Behav."},{"key":"ref_262","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s10919-007-0042-6","article-title":"The sound of symmetry revisited: Subjective and objective analyses of voice","volume":"32","author":"Hughes","year":"2008","journal-title":"J. Nonverbal Behav."},{"key":"ref_263","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.evolhumbehav.2014.10.004","article-title":"The sound of female shape: A redundant signal of vocal and facial attractiveness","volume":"36","author":"Abend","year":"2015","journal-title":"Evol. Hum. Behav."},{"key":"ref_264","doi-asserted-by":"crossref","unstructured":"Hill, A.K., C\u00e1rdenas, R.A., Wheatley, J.R., Welling, L.L.M., Burriss, R.P., Claes, P., Apicella, C.L., McDaniel, M.A., Little, A.C., and Shriver, M.D. (2016). Are there vocal cues to human developmental stability? Relationships between facial fluctuating asymmetry and voice attractiveness. Evol. Hum. Behav.","DOI":"10.1016\/j.evolhumbehav.2016.10.008"},{"key":"ref_265","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/S1090-5138(03)00080-1","article-title":"The relationship between shape symmetry and perceived skin condition in male facial attractiveness","volume":"25","author":"Jones","year":"2004","journal-title":"Evol. Hum. Behav."},{"key":"ref_266","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1597\/04-122r1.1","article-title":"The Pittsburgh Oral-Facial Cleft study: Expanding the cleft phenotype. Background and justification","volume":"43","author":"Weinberg","year":"2006","journal-title":"Cleft Palate Cranio-Fac. J."},{"key":"ref_267","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1034\/j.1600-0544.2002.02196.x","article-title":"Cleft lip with or without cleft palate and dermatoglyphic asymmetry: Evaluation of a Chinese population","volume":"5","author":"Neiswanger","year":"2002","journal-title":"Orthod. Craniofac. Res."},{"key":"ref_268","first-page":"1657","article-title":"Facial anthropometry: A tool for quantitative evaluation in patients with peripheral facial paralysis","volume":"6","year":"2015","journal-title":"Int. J. Sci. Eng. Res."},{"key":"ref_269","first-page":"1851","article-title":"Selective breeding for high endurance running increases hindlimb symmetry","volume":"59","author":"Garland","year":"2005","journal-title":"Evolution"},{"key":"ref_270","doi-asserted-by":"crossref","unstructured":"Trivers, R., Palestis, B.G., and Manning, J.T. (2013). The symmetry of children\u2019s knees is linked to their adult sprinting speed and their willingness to sprint in a long-term Jamaican study. PLoS ONE, 8.","DOI":"10.1371\/journal.pone.0072244"},{"key":"ref_271","doi-asserted-by":"crossref","unstructured":"Trivers, R., Fink, B., Russell, M., McCarty, K., James, B., and Palestis, B.G. (2014). Lower body symmetry and running performance in elite Jamaican track and field athletes. PLoS ONE, 9.","DOI":"10.1371\/journal.pone.0113106"},{"key":"ref_272","unstructured":"Oxford, M. (2013). The Effect of Muscle Imbalance on Running Performance in Collegiate Level Athletes. [Master\u2019s Thesis, University of Windsor]."},{"key":"ref_273","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S1090-5138(03)00081-3","article-title":"Fluctuating asymmetry and low back pain","volume":"25","author":"Egan","year":"2004","journal-title":"Evol. Hum. Behav."},{"key":"ref_274","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1097\/00007632-199704010-00014","article-title":"Fluctuating asymmetry and vertebral malformation: A study of palmar dermatoglyphics in congenital spinal deformities","volume":"22","author":"Goldberg","year":"1997","journal-title":"Spine"},{"key":"ref_275","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1111\/j.1600-0447.2012.01869.x","article-title":"Dermatoglyphic asymmetries and fronto-striatal dysfunction in young adults reporting non-clinical psychosis","volume":"126","author":"Mittal","year":"2012","journal-title":"Acta Psychiatr. Scand."},{"key":"ref_276","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s11065-010-9148-4","article-title":"The basics of brain development","volume":"20","author":"Stiles","year":"2010","journal-title":"Neuropsychol. Rev."},{"key":"ref_277","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1038\/mp.2014.148","article-title":"Schizophrenia genetics: Emerging themes for a complex disorder","volume":"20","author":"Kavanagh","year":"2015","journal-title":"Mol. Psychiatry"},{"key":"ref_278","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0920-9964(00)00044-X","article-title":"Dermatoglyphic fluctuating asymmetry and atypical handedness in schizophrenia","volume":"50","author":"Reilly","year":"2001","journal-title":"Schizophr. Res."},{"key":"ref_279","unstructured":"Cohen, J. (1988). Statistical Power Analysis for the Behavior Sciences, Lawrance Eribaum Association."},{"key":"ref_280","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1001\/archneurol.2010.47","article-title":"Connecting genes to brain in the autism spectrum disorders","volume":"67","author":"Abrahams","year":"2010","journal-title":"Arch. Neurol."},{"key":"ref_281","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.tics.2011.07.003","article-title":"Genetics of autism spectrum disorders","volume":"15","author":"Geschwind","year":"2011","journal-title":"Trends Cognit. Sci."},{"key":"ref_282","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.intell.2006.03.013","article-title":"Fluctuating asymmetry and intelligence","volume":"35","author":"Bates","year":"2007","journal-title":"Intelligence"},{"key":"ref_283","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1098\/rspb.1997.0115","article-title":"Fluctuating asymmetry and psychometric intelligence","volume":"264","author":"Furlow","year":"1997","journal-title":"Proc. R. Soc. Lond. B. Biol. Sci."},{"key":"ref_284","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.intell.2004.07.007","article-title":"Intelligence tests with higher g-loadings show higher correlations with body symmetry: Evidence for a general fitness factor mediated by developmental stability","volume":"33","author":"Prokosch","year":"2005","journal-title":"Intelligence"},{"key":"ref_285","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.intell.2010.04.003","article-title":"Smarter people are (a bit) more symmetrical: A meta-analysis of the relationship between intelligence and fluctuating asymmetry","volume":"38","author":"Banks","year":"2010","journal-title":"Intelligence"},{"key":"ref_286","doi-asserted-by":"crossref","first-page":"161","DOI":"10.3758\/BF03332043","article-title":"Hand preference and developmental instability","volume":"21","author":"Yeo","year":"1993","journal-title":"Psychobiology"},{"key":"ref_287","doi-asserted-by":"crossref","first-page":"8730","DOI":"10.1523\/JNEUROSCI.3287-14.2015","article-title":"Linkage analysis in a Dutch population isolate shows no major gene for left-handedness or atypical language lateralization","volume":"35","author":"Somers","year":"2015","journal-title":"J. Neurosci."},{"key":"ref_288","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1002\/ajhb.20047","article-title":"Fluctuating asymmetry predicts human reactive aggression","volume":"16","author":"Benderlioglu","year":"2004","journal-title":"Am. J. Hum. Biol."},{"key":"ref_289","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1098\/rspb.1998.0255","article-title":"Developmental stability and human violence","volume":"265","author":"Furlow","year":"1998","journal-title":"Proc. R. Soc. Lond. B. Biol. Sci."},{"key":"ref_290","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1002\/ajhb.22727","article-title":"Self-reported aggressiveness is not related to developmental instability","volume":"27","author":"Duyar","year":"2015","journal-title":"Am. J. Hum. Biol."},{"key":"ref_291","first-page":"32","article-title":"Facial symmetry is not a reliable cue of aggressive behavior","volume":"3","author":"Pelin","year":"2012","journal-title":"Eurasian J. Anthropol."},{"key":"ref_292","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s12110-998-1011-4","article-title":"Fluctuating asymmetry and aggression in boys","volume":"9","author":"Manning","year":"1998","journal-title":"Hum. Nat."},{"key":"ref_293","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.paid.2012.06.012","article-title":"Facial asymmetry and aggression in Spanish adolescents","volume":"53","author":"Fink","year":"2012","journal-title":"Personal. Individ. Differ."},{"key":"ref_294","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.jrp.2011.08.003","article-title":"Are pro-social or socially aversive people more physically symmetrical? Symmetry in relation to over 200 personality variables","volume":"45","author":"Holtzman","year":"2011","journal-title":"J. Res. Personal."},{"key":"ref_295","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1038\/506150a","article-title":"Statistical errors","volume":"506","author":"Nuzzo","year":"2014","journal-title":"Nature"},{"key":"ref_296","doi-asserted-by":"crossref","unstructured":"Head, M.L., Holman, L., Lanfear, R., Kahn, A.T., and Jennions, M.D. (2015). The extent and consequences of p-hacking in science. PLoS Biol., 13.","DOI":"10.1371\/journal.pbio.1002106"},{"key":"ref_297","doi-asserted-by":"crossref","first-page":"311","DOI":"10.5735\/086.046.0501","article-title":"Final collapse of the Neyman-Pearson decision theoretic framework and rise of the neoFisherian","volume":"46","author":"Hurlbert","year":"2009","journal-title":"Ann. Zool. Fenn."},{"key":"ref_298","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1111\/j.1442-9993.2009.01946.x","article-title":"Misprescription and misuse of one-tailed tests","volume":"34","author":"Lombardi","year":"2009","journal-title":"Austral Ecol."},{"key":"ref_299","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.ecolind.2015.05.014","article-title":"Confirmation bias in studies of fluctuating asymmetry","volume":"57","author":"Kozlov","year":"2015","journal-title":"Ecol. Indic."}],"container-title":["Symmetry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2073-8994\/8\/12\/154\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T19:28:40Z","timestamp":1760210920000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2073-8994\/8\/12\/154"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,16]]},"references-count":299,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2016,12]]}},"alternative-id":["sym8120154"],"URL":"https:\/\/doi.org\/10.3390\/sym8120154","relation":{},"ISSN":["2073-8994"],"issn-type":[{"value":"2073-8994","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,16]]}}}