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An overarching framework is currently still missing, and establishing such is the central research approach in this paper. This paper provides an overview of the current demands on the manufacturing industry from the perspective of digitalization and sustainability. On the basis of the developed fundamentals and parameters, a superordinate framework is proposed that allows the modelling and simulation of energy-specific properties on several product and process levels. A detailed description of the individual methods concludes this work and demonstrates their application potential in an industrial context. As a result, this integrated conceptual framework offers the possibility of optimizing the production system, in relation to different energy flexibility criteria.<\/jats:p>","DOI":"10.3390\/systems11020100","type":"journal-article","created":{"date-parts":[[2023,2,13]],"date-time":"2023-02-13T01:48:56Z","timestamp":1676252936000},"page":"100","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Holistic System Modelling and Analysis for Energy-Aware Production: An Integrated Framework"],"prefix":"10.3390","volume":"11","author":[{"given":"Peter","family":"Hehenberger","sequence":"first","affiliation":[{"name":"\u201cSmart Mechatronics Engineering\u201d Research Group, University of Applied Sciences Upper Austria, 4600 Wels, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4330-0981","authenticated-orcid":false,"given":"Dominik","family":"Leherbauer","sequence":"additional","affiliation":[{"name":"\u201cSmart Mechatronics Engineering\u201d Research Group, University of Applied Sciences Upper Austria, 4600 Wels, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6363-5754","authenticated-orcid":false,"given":"Olivia","family":"Penas","sequence":"additional","affiliation":[{"name":"Quartz Laboratory (EA7393), ISAE-Supm\u00e9ca, 93400 Saint-Ouen-sur-Seine, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7873-2904","authenticated-orcid":false,"given":"Romain","family":"Delabeye","sequence":"additional","affiliation":[{"name":"Quartz Laboratory (EA7393), ISAE-Supm\u00e9ca, 93400 Saint-Ouen-sur-Seine, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1564-8830","authenticated-orcid":false,"given":"Stanislao","family":"Patalano","sequence":"additional","affiliation":[{"name":"Fraunhofer J-Lab IDEAS, Department of Industrial Engineering, University of Naples Federico II, P.le V. 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