{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T16:54:33Z","timestamp":1764262473623,"version":"3.46.0"},"reference-count":74,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Scientific Research Start-up Funding for Young Teachers at Shenzhen University","award":["RC20240301"],"award-info":[{"award-number":["RC20240301"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Systems"],"abstract":"<jats:p>Over-the-counter medication electronic health records (OTC-EHRs) play a significant role in users\u2019 self-medication practices. In this study, we consider the potential advantages of wearable smart devices in health management, along with the information processing capabilities of artificial intelligence (AI), and we propose a conceptual design for an AI-assisted wearable OTC-EHR system. Our objective was to systematically explore the relationship between eHealth literacy, users\u2019 attitudes, and willingness to use the proposed system, as well as to discuss AI interventions. Internet users from China participated in an online survey examining eHealth literacy, subjective attitudes, and motivation to use this conceptual design. Descriptive statistical, correlation, difference, and regression analyses were conducted on 372 valid responses to test the research hypotheses. The results showed that the wearable-device-based OTC-EHR system with AI assistance was accepted by most responders and positively associated with eHealth literacy, which was, in turn, associated with decision-making preferences. This study suggests that AI may be perceived as an auxiliary tool for medication-related decision-making and is associated with the degree of eHealth literacy. Individuals with higher eHealth literacy are more likely to make autonomous decisions, whereas those with lower literacy will potentially rely more on AI support and professional guidance.<\/jats:p>","DOI":"10.3390\/systems13121070","type":"journal-article","created":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T16:31:52Z","timestamp":1764261112000},"page":"1070","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["eHealth Literacy, Attitudes, and Willingness to Use an Artificial Intelligence-Assisted Wearable OTC-EHR System for Self-Medication: An Empirical Study Exploring AI Interventions"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7430-0880","authenticated-orcid":false,"given":"Guyue","family":"Tang","sequence":"first","affiliation":[{"name":"College of Art and Design, Division of Arts, Shenzhen University, Shenzhen 518060, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8443-986X","authenticated-orcid":false,"given":"Zhidiankui","family":"Xu","sequence":"additional","affiliation":[{"name":"School of Design, Jiangnan University, Wuxi 214122, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6280-5750","authenticated-orcid":false,"given":"Shinichi","family":"Koyama","sequence":"additional","affiliation":[{"name":"Institute of Art and Design, University of Tsukuba, Tsukuba 305-8574, Ibaraki, Japan"}]}],"member":"1968","published-online":{"date-parts":[[2025,11,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Tang, G., Izumi, K., Izumisawa, M., and Koyama, S. 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